CIZ1 antibody

Principal name

CIZ1 antibody

Alternative names for CIZ1 antibody

LSFR1, NP94, ZNF356, Cip1-interacting zinc finger protein, CDKN1A-interacting zinc finger protein 1, Nuclear protein NP94, Zinc finger protein 356

SwissProt ID

Q9ULV3 (Human)

Gene ID

25792 (CIZ1)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), GP (Guinea Pig), Ms (Mouse), Rb (Rabbit), Rt (Rat), Eq (Equine)

Available hosts

Rabbit, Mouse, Goat

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), ELISA (detection) (E(detection)), Enzyme Immunoassay (E)

Background of CIZ1 antibody

CIZ1 (Cip1 interacting zinc-finger protein) was identified as a protein that associates with the cell-cycle inhibiting protein, p21 (Cip1/Waf1). CIZ1 is a member of the matrin 3 protein family and has been shown to bind DNA consensus sequences and co-localize with PCNA during replication. In breast cancer cells, CIZ1 was shown to associate with Cdk2 and dynein light chain 1 (DLC1), a cytoskeletal signaling protein involved in cell cycle regulation and tumorigenesis. Studies of the role of CIZ1 in breast tumorigenesis revealed that CIZ1 is an estrogen-responsive gene that functions as a coactivator of the estrogen receptor. Targeted depletion of CIZ1 inhibits entry into S-phase. This finding along with evidence that CIZ1 interacts with multiple cell cycle regulatory proteins and localizes to DNA replication foci, indicates that CIZ1 plays a critical role in the regulation of DNA replication.

General readings

Warder,D.E. (2003) J. Biomed. Sci. 10 (4), 406-417

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CIZ1 (C-term) antibody

AP32951PU-N (0.3 µg/ml) staining of HeLa nuclear lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €340.00
  Acris Antibodies GmbH

CIZ1 antibody

WB Suggested Anti-CIZ1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:12500; Positive Control: HT1080 cell lysate; CIZ1 is supported by BioGPS gene expression data to be expressed in HT1080 Rabbit IgG Purified Bov, Can, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CIZ1 antibody

WB Suggested Anti-CIZ1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Transfected 293T Rabbit IgG Purified Eq, Hu P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

CIZ1 antibody

CIZ1 Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

CIZ1 antibody

Human Lung; CIZ1 antibody - C-terminal region (ARP38956_P050) in Human Lung cells using Immunohistochemistry Rabbit Aff - Purified Hu P, WB
50 µg / €350.00
  AVIVA Systems Biology

CIZ1 antibody

Western Blot and  Immunoprecipitation: CIZ1 Antibody [NB100-74623] - Detection of Human CIZ1 on HeLa whole cell lysate using NB100-74623. CIZ1 was also  immunoprecipitated by rabbit anti-CIZ1 antibody NB100-74624. Rabbit IgG Aff - Purified Hu IP, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

CIZ1 antibody

Western Blot and  Immunoprecipitation: CIZ1 Antibody [NB100-74624] - Detection of Human CIZ1on HeLa whole cell lysate using NB100-74624. CIZ1 was also immunoprecipitated by rabbit anti-CIZ1 antibody NB100-74623. Rabbit IgG Aff - Purified Hu IP, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CIZ1 (transcript variant 1)

CIZ1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

CIZ1

CIZ1 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

CIZ1 293T Cell Transient Overexpression Lysate(Denatured)

CIZ1 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

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