Claspin antibody

Principal name

Claspin antibody

Alternative names for Claspin antibody

CLSPN

SwissProt ID

Q80YR7 (Mouse), Q9DF50 (Xenla), Q9HAW4 (Human)

Gene ID

63967 (CLSPN)

Available reactivities

Hu (Human)

Available hosts

Rabbit

Available applications

Immunoprecipitation (IP), PLA/Proximity ligation assay (PLA), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Claspin antibody

Claspin is a cell cycle regulated adaptor protein which peaks at the S/G2 phase and plays an essential role during checkpoint-mediated cell cycle arrest, in response to DNA damage or inhibition of DNA replication.
Following replication stress, the phosphorylation of threonine 916 and serine residues 945/982 on claspin, enables its association with Chk1 (cell cycle checkpoint kinasomologue 1), a protein kinase responsible for the initiation of G2 arrest in response to DNA damage. Claspin has also been shown to interact with ATR (the ATM- and Rad3-related protein kinase) and Rad9, further checkpoint proteins involved in Chk1 activation.

3 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Claspin antibody

Claspin Rabbit Hu IP, WB
0.1 ml / €400.00
  Abnova Taiwan Corp.

Claspin (exons 11, 12, 13) antibody

Western Blot and  Immunoprecipitation: Claspin Antibody [NB100-247] - Detection of human Claspin on HeLa whole cell lysate using NB100-247. Rabbit Aff - Purified Hu IP, PLA, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Claspin (exon 15) antibody

Western Blot: Claspin Antibody [NB100-248] - Samples:  Whole cell lysate from HeLa.  Antibodies: Rabbit anti-Claspin antibody used for WB at 0.1 mcg/ml (A) and 1 mcg/ml.  Detection: Chemiluminescence with exposure times of 30 seconds._x000d_ Rabbit Aff - Purified Hu IP, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

3 Item(s)

per page
  • LinkedIn