Clathrin heavy chain antibody

Principal name

Clathrin heavy chain antibody

Alternative names for Clathrin heavy chain antibody

CLTC, CLH17, CLTCL2, KIAA0034, Membrane Vesicle Marker, Clathrin heavy chain on chromosome 17

SwissProt ID

P49951 (Bovin), Q00610 (Human)

Gene ID

1213 (CLTC), 281080

Available reactivities

Bov (Bovine), Hu (Human), Ms (Mouse), Por (Porcine), Rt (Rat), Amph (Amphibian), Mky (Monkey), Can (Canine), Hst (Hamster), Prim (Primate), Chk (Chicken), Eq (Equine), Rb (Rabbit), Xen (Xenopus), Ze (Zebrafish), Gorilla

Available hosts

Mouse, Goat, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Flow Cytometry (F), Paraffin Sections (P), Frozen Sections (C)

Background of Clathrin heavy chain antibody

Clathrin is a submembrane protein that polymerizes into coat-like lattices, which results in membrane invagination. The basic oligomers are composed of three clathrin heavy chain (180 kDa) and three light chain (30 kDa) subunits and the process of polymerization is dynamically regulated by the light chains. Interaction of clathrin with the plasma membrane is mediated by adaptor proteins (AP1-4) specific for different cellular compartments. Another proteins, such as endophilin, epsin and amphiphysin are involved in membrane invagination and clathrin rearrangements. Finally, dynamin functions at the fission stage of clathrin-mediated endocytosis.

General readings

General / background references:Liu SH et al. A novel clathrin homolog that co-distributes with cytoskeletal components functions in the trans-Golgi network. EMBO J 20:272-84 (2001). PubMed PMID: 11226177
Beattie EC et al. NGF signals through TrkA to increase clathrin at the plasma membrane and enhance clathrin-mediated membrane trafficking. J Neurosci 20:7325-33 (2000). PubMed PMID: 11007890
Wilde A et al. EGF receptor signaling stimulates SRC kinase phosphorylation of clathrin, influencing clathrin redistribution and EGF uptake. Cell 96:677-87 (1999). PubMed PMID: 10089883
Nathke IS et al. Folding and trimerization of clathrin subunits at the triskelion hub. Cell 68:899-910 (1992). PubMed PMID: 1547490

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Clathrin heavy chain antibody

Anti-CLTC antibody IHC of human adrenal. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 3.75 ug/ml. Goat Purified Hu P
50 µg / €345.00
  OriGene Technologies, Inc.

Clathrin heavy chain (N-term) antibody

Clathrin heavy chain Goat IgG Aff - Purified Can, Hu, Mky, Ms, Rt ICC/IF, WB
20 µl / €50.00
  SICGEN

Clathrin heavy chain (N-term) antibody

Clathrin heavy chain Goat IgG Aff - Purified Can, Hu, Mky, Ms, Rt ICC/IF, WB
0.4 mg / €320.00
  SICGEN

Clathrin heavy chain antibody

Immunofluorescence staining of clathrin in human HeLa cell line using anti-clathrin (BF-06; green). Actin cytoskeleton decorated by phalloidin (red) and cell nuclei stained with DAPI (blue). Mouse IgM BF-06 Purified Bov, Hu, Ms, Por, Rt E, F, ICC/IF, IP, WB
0.1 mg / €270.00
  Acris Antibodies GmbH

Clathrin heavy chain antibody

Clathrin heavy chain Mouse IgM CHC5.9 Purified Amph, Bov, Hu, Por, Rt C, WB
0.1 mg / €280.00
  Acris Antibodies GmbH

Clathrin heavy chain antibody

CLTC polyclonal antibody (A01), Lot # O51130JC01 Western Blot analysis of CLTC expression in MES-SA/Dx5 ( Cat # L021V1 ). Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Clathrin heavy chain antibody

Proximity Ligation Analysis (PLA) of protein-protein interactions between HIP1 and CLTC. HeLa cells were stained with anti-HIP1 rabbit purified polyclonal 1:1200 and anti-CLTC mouse monoclonal antibody 1:50. Signals were detected by Duolink® 30 Detection Kit 613(red), and nuclei were counterstained with DAPI (blue). Each red dot represents the detection of protein-protein interaction complex. Mouse IgG2a 2E5 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Clathrin heavy chain antibody

Clathrin heavy chain Mouse IgM STo 3H9 Purified Hu WB
0.1 mg / €420.00
  Novus Biologicals Inc.

Clathrin heavy chain antibody

Clathrin heavy chain Mouse IgG1 TD.1 Purified Bov, Hu, Ms, Rt WB
0.1 ml / €400.00
  Novus Biologicals Inc.

Clathrin heavy chain antibody

Clathrin heavy chain Mouse IgG1 X22 Ig Fraction Bov, Hu, Mky, Ms, Rt F, ICC/IF, IP, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

Clathrin heavy chain antibody

Clathrin heavy chain Mouse IgM BF-06 Purified Bov, Hu, Ms, Por, Rt E, F, ICC/IF, IP, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

Clathrin heavy chain antibody

Clathrin heavy chain Goat Aff - Purified Bov, Can, Hu, Ms, Rt P
50 µg / €480.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Clathrin heavy chain

Clathrin heavy chain Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Clathrin heavy chain

Clathrin heavy chain Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

14 Item(s)

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