Claudin-2 / CLDN2 antibody

Principal name

Claudin-2 / CLDN2 antibody

Alternative names for Claudin-2 / CLDN2 antibody

SP82, CLD2

SwissProt ID

O88552 (Mouse), P57739 (Human), Q765P1 (Bovin), Q95KM6 (Canfa)

Gene ID

9075 (CLDN2), 12738 (Cldn2)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Chk (Chicken), Por (Porcine), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Claudin-2 / CLDN2 antibody

The Claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteinsare known to localize to tight junctions, including the Claudins, Occludin and junction adhesion molecule (JAM). Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Emerging evidence suggests that the Claudin family of proteins regulates transport through tight junctions via differential discrimination for solute size and charge. Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions.

General readings

Escaffit,F., (2005) J. Cell. Physiol. 203 (1), 15-26

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Claudin-2 / CLDN2 antibody

  Rabbit Polyclonal Anti-Claudin 2 Antibody  
Western blot analysis on NIH-3T3 cell lysate using Claudin 2 Antibody Rabbit IgG Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Claudin-2 / CLDN2 antibody

Immunohistochemistry analysis of Claudin-2 Antibody (Cat.-No AP06063PU-N) in paraffin-embedded human breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Claudin-2 / CLDN2 (N-term) antibody

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with CLDN2 (Human N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Claudin-2 / CLDN2 (C-term) antibody

Western blot analysis of anti-CLDN2 Antibody (C-term) in mouse kidney tissue lysates (35ug/lane). CLDN2(arrow) was detected using the purified Pab (1:190 dilution). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Claudin-2 / CLDN2 (N-term) antibody

Formalin-Fixed, Paraffin-Embedded Human Kidney stained with Claudin-2 / CLDN2 Antibody Cat.-No AP23596PU-N at 5 µg/ml after heat-induced antigen retrieval. Rabbit Purified Hu P, WB
0.2 ml / €470.00
  Acris Antibodies GmbH

Claudin-2 / CLDN2 (C-term Y195) antibody

CLDN2 Antibody (C-term pTyr195) (Cat. #AP50945PU-N)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CLDN2 Antibody (C-term pTyr195) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Claudin-2 / CLDN2 (C-term Y224) antibody

CLDN2 Antibody (C-term pTyr224) (Cat. #AP50946PU-N)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CLDN2 Antibody (C-term pTyr224) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Claudin-2 / CLDN2 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Claudin 2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P, WB
50 µg / €230.00
  Assay Biotech

Claudin-2 / CLDN2 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Claudin 2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

CLDN2 - human gene knockout kit via CRISPR

CLDN2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

CLDN2 - human gene knockout kit via CRISPR

CLDN2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CLDN2 - human gene knockout kit via CRISPR

CLDN2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CLDN2 - human gene knockout kit via CRISPR

CLDN2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cldn2 - mouse gene knockout kit via CRISPR

Cldn2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Cldn2 - mouse gene knockout kit via CRISPR

Cldn2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cldn2 - mouse gene knockout kit via CRISPR

Cldn2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cldn2 - mouse gene knockout kit via CRISPR

Cldn2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Claudin-2 / CLDN2

  Recombinant protein of human claudin 2 (CLDN2)  
Claudin-2 / CLDN2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

CLDN2 overexpression lysate

CLDN2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

CLDN2 overexpression lysate

CLDN2 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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