Claudin-2 / CLDN2 antibody

Principal name

Claudin-2 / CLDN2 antibody

Alternative names for Claudin-2 / CLDN2 antibody

SP82, CLD2

SwissProt ID

O88552 (Mouse), P57739 (Human), Q765P1 (Bovin), Q95KM6 (Canfa)

Gene ID

9075 (CLDN2), 2907509 (Q6CFX1)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Chk (Chicken), Por (Porcine), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Claudin-2 / CLDN2 antibody

The claudin superfamily consists of structurally related proteins that are important structural and functional components of tight junctions. Claudin-2, also known as CLDN2 or SP82, is a 230 amino acid multi-pass membrane protein that localizes to the cell junctions and belongs to the claudin superfamily. Able to form homopolymers of heteropolymers with other claudin family members, claudin-2 plays an essential role in mediating calcium-independent cell-adhesion activity that is necessary for tight junction-specific obliteration of the intercellular space. Overexpression of claudin-2 is associated with a variety of diseases, including lung cancer, colorectal cancer, gastrointestinal carcinomas and inflammatory bowel disease, further affirming the importance of claudin-2 in cell adhesion. The gene encoding claudin-2 maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes.

General readings

Escaffit,F., (2005) J. Cell. Physiol. 203 (1), 15-26

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Claudin-2 / CLDN2 antibody

Western blot analysis on NIH-3T3 cell lysate using Claudin 2 Antibody Rabbit IgG Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Claudin-2 / CLDN2 antibody

Immunohistochemistry analysis of Claudin-2 Antibody (Cat.-No AP06063PU-N) in paraffin-embedded human breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Claudin-2 / CLDN2 (N-term) antibody

Formalin-fixed and paraffin-embedded human hepatocarcinoma tissue reacted with CLDN2 (Human N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Claudin-2 / CLDN2 (C-term) antibody

Western blot analysis of anti-CLDN2 Antibody (C-term) in mouse kidney tissue lysates (35ug/lane). CLDN2(arrow) was detected using the purified Pab (1:190 dilution). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Claudin-2 / CLDN2 (N-term) antibody

Formalin-Fixed, Paraffin-Embedded Human Kidney stained with Claudin-2 / CLDN2 Antibody Cat.-No AP23596PU-N at 5 µg/ml after heat-induced antigen retrieval. Rabbit Purified Hu P, WB
0.2 ml / €470.00
  Acris Antibodies GmbH

Claudin-2 / CLDN2 (C-term Y195) antibody

CLDN2 Antibody (C-term pTyr195) (Cat. #AP50945PU-N)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CLDN2 Antibody (C-term pTyr195) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Claudin-2 / CLDN2 (C-term Y224) antibody

CLDN2 Antibody (C-term pTyr224) (Cat. #AP50946PU-N)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CLDN2 Antibody (C-term pTyr224) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Claudin-2 / CLDN2 antibody

Claudin-2 / CLDN2 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Claudin-2 / CLDN2 antibody

Detection limit for recombinant GST tagged CLDN2 is approximately 0.03ng/ml as a capture antibody. Mouse IgG2a 3F1 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Claudin-2 / CLDN2 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Claudin 2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P, WB
50 µg / €205.00
  Assay Biotech

Claudin-2 / CLDN2 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Claudin 2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, P, WB
0.1 mg / €310.00
  Assay Biotech

Claudin-2 / CLDN2 antibody

Human HepG2; WB Suggested Anti-CLDN2 Antibody Titration: 1.25ug/ml. Positive Control: HepG2 cell lysate; CLDN2 antibody - N-terminal region (ARP42845_T100) in Human HepG2 cells using Western Blot Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Por, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

Claudin-2 / CLDN2 antibody

Immunohistochemical analysis of Claudin 2 staining in human tonsil formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rt ICC/IF, P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

Claudin-2 / CLDN2 antibody

Immunohistochemical analysis of Claudin 2 staining in human tonsil formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rt ICC/IF, P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

Claudin-2 / CLDN2 antibody

Immunohistochemical analysis of Claudin 2 staining in human tonsil formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rt ICC/IF, P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

Claudin-2 / CLDN2 antibody

Immunohistochemistry: Claudin 2 Antibody [NB100-91710] -  Claudin 2 (S219) antibody [NB100-91710] - in paraffin-embedded human breast carcinoma tissue Rabbit IgG Aff - Purified Hu, Ms P, WB
0.1 mg / €420.00
  Novus Biologicals Inc.

Claudin-2 / CLDN2 antibody

Claudin-2 / CLDN2 Rabbit IgG Aff - Purified Hu, Ms E, P, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

Claudin-2 / CLDN2 antibody

Claudin-2 / CLDN2 Rabbit IgG Aff - Purified Hu, Ms E, P, WB
50 µg / €290.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Claudin-2 / CLDN2

Claudin-2 / CLDN2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Claudin-2 / CLDN2

Claudin-2 / CLDN2 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

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