Claudin-4 / CLDN4 antibody

Principal name

Claudin-4 / CLDN4 antibody

Alternative names for Claudin-4 / CLDN4 antibody

CPER, CPETR1, CPE-R, WBSCR8, CPE-Receptor, Clostridium perfringens enterotoxin receptor, Williams-Beuren syndrome chromosomal region 8 protein

SwissProt ID

O14493 (Human), O19005 (Chlae), O35054 (Mouse), Q6BBL6 (Bovin)

Gene ID

1364 (CLDN4)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Por (Porcine), Rb (Rabbit), Sh (Sheep), Bov (Bovine), Can (Canine), Eq (Equine)

Available hosts

Rabbit, Mouse

Available applications

Frozen Sections (C), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Flow Cytometry (F), Immunoprecipitation (IP)

Background of Claudin-4 / CLDN4 antibody

The Claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the Claudins, Occludin and junction adhesion molecule (JAM). Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Claudin expression is highly restricted to specific regions of different tissues and variations of Claudin expression may have an important role in transcellular transport through tight junctions. In rat liver, claudin-3 is uniformly expressed, whereas in the pancreas, claudin-3 is expressed in junctions of the duct epithelia and junctions of acinar cells. Claudin-3 binds the peptide toxin Clostridium perfringens enterotoxin (CPE) at the cell surface via the second extracellular loop of claudin-3. The gene encoding human claudin-3 maps to chromosome 7q11.23.

General readings

Mitic LL, Unger VM, and Anderson JM. Expression, solubilization, and biochemical characterization of the tight junction transmembrane protein claudin-4. Protein Sci. 2003; 12:218-27.
Paperna T, Peoples R, Wang YK, et al. Genes for the CPE receptor (CPETR1) and the human homolog of RVP1 (CPETR2) are localized within the Williams-Beuren syndrome deletion. Genomics 1998; 54:453-9.
Morin PJ. Claudin proteins in human cancer: promising new targets for diagnosis and therapy. Cancer Res. 2005; 65:9603-6.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Claudin-4 / CLDN4 antibody

AP15489PU Claudin-4 antibody staining of Human Tonsil. Rabbit Purified Hu, Ms P
0.5 ml / €360.00
  Acris Antibodies GmbH

Claudin-4 / CLDN4 antibody

AP15489PU Claudin-4 antibody staining of Human Tonsil. Rabbit Purified Hu, Ms P
1 ml / €440.00
  Acris Antibodies GmbH

Claudin-4 / CLDN4 antibody

AP15489PU Claudin-4 antibody staining of Human Tonsil. Rabbit Purified Hu, Ms P
0.1 ml / €180.00
  Acris Antibodies GmbH

Claudin-4 / CLDN4 antibody

Western blot analysis of extracts from HeLa cells, using Claudin 4 antibody (#TA313674).The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Claudin-4 / CLDN4 (C-term) antibody

Western blot analysis of CLAUDIN4 in human colon tissue lysate with CLAUDIN4 antibody at 1 ug/ml Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Claudin-4 / CLDN4 antibody

Predicted band size: 22 kDa . Positive control: HT-29 cell lysate. Recommended dilution: 1/2000-5000. (Gel: 10%SDS-PAGE Lysate: 30 ug Primary antibody: 1/700 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 30 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Claudin-4 / CLDN4 antibody

Predicted band size: 22 kDa . Positive control: HT-29 cell lysate. Recommended dilution: 1/2000-5000. (Gel: 10%SDS-PAGE Lysate: 30 ug Primary antibody: 1/1100 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 30 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Claudin-4 / CLDN4 antibody

Host: Rabbit; Target Name: CLDN4; Sample Tissue: large intestine Tumor lysates; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, Hu, Ms, Por, Rb WB
50 µg / €325.00
  OriGene Technologies, Inc.

Claudin-4 / CLDN4 antibody

Western blot analysis of Claudin 4 expression in HeLa cells Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Claudin-4 / CLDN4 antibody

Immunohistochemistry analysis of Claudin 4 antibody (Cat.-No AP06065PU-N) in paraffin-embedded human breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Claudin-4 / CLDN4 (C-term) antibody

Prostate: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu, Ms E, P
50 µl / €470.00
  Acris Antibodies GmbH

Claudin-4 / CLDN4 (C-term) antibody

Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Purified Hu, Ms P
0.25 ml / €470.00
  Acris Antibodies GmbH

Claudin-4 / CLDN4 (C-term) antibody

Western blot analysis of CLDN4 Antibody (C-term) (Cat. #AP50949PU-N) in mouse heart tissue lysates (35µg/lane). CLDN4 (arrow) was detected using the purified Pab. Rabbit Ig Aff - Purified Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Claudin-4 / CLDN4 (C-term) Control Peptide

Claudin-4 / CLDN4
50 µg / €160.00
  Acris Antibodies GmbH

Claudin-4 / CLDN4 antibody

Formalin fixed paraffin embedded human ovarian carcinoma stained with Claudin 4 antibody. DP156 Rabbit Purified Hu, Ms C, P
1 ml / €570.00
  Acris Antibodies GmbH

Claudin-4 / CLDN4 antibody

Formalin fixed paraffin embedded human ovarian carcinoma stained with Claudin 4 antibody. DP156 Rabbit Purified Hu, Ms C, P
0.5 ml / €380.00
  Acris Antibodies GmbH

Claudin-4 / CLDN4 antibody

Claudin-4 / CLDN4 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Claudin-4 / CLDN4 antibody

Western Blot analysis of CLDN4 expression in transfected 293T cell line (H00001364-T01) by CLDN4 MaxPab polyclonal antibody.

Lane1:CLDN4 transfected lysate(22.99 KDa).
Lane2:Non-transfected lysate. Mouse Serum Hu E(detection), F, WB
50 µl / €370.00
  Abnova Taiwan Corp.

Claudin-4 / CLDN4 antibody

Immunoprecipitation of CLDN4 transfected lysate using anti-CLDN4 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with CLDN4 MaxPab mouse polyclonal antibody (B01) (H00001364-B01). Rabbit Serum Hu E(detection), IP
0.1 ml / €380.00
  Abnova Taiwan Corp.

Claudin-4 / CLDN4 antibody

Claudin-4 / CLDN4 Mouse IgG3 4A4 Ascites Hu E, WB
0.2 ml / €370.00
  Abnova Taiwan Corp.

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