CLCN6 antibody

Principal name

CLCN6 antibody

Alternative names for CLCN6 antibody

Chloride channel protein 6, ClC-6, ClC6, KIAA0046, Chloride transport protein 6

SwissProt ID

O35454 (Mouse), P51797 (Human), Q9TT16 (Rabit)

Gene ID

1185 (CLCN6), 26372 (Clcn6)

Available reactivities

Bov (Bovine), Can (Canine), Chk (Chicken), Hu (Human), Ms (Mouse), Rb (Rabbit), Rt (Rat), Eq (Equine), GP (Guinea Pig), Por (Porcine)

Available hosts

Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E)

Background of CLCN6 antibody

The family of voltage-dependent chloride channels (CLCs) regulate cellular trafficking of chloride ions, a critical component of all living cells. CLCs regulate excitability in muscle and nerve cells, aid in organic solute transport and maintain cellular volume. The genes encoding human CLC-1 through CLC-7 map to chromosomes 7, 3q26, 4q32, Xp22, Xp11, 1p36 and 16p13, respectively. CLC-1 is highly expressed in skeletal muscle. Mutations in the gene encoding CLC-1 lead to myotonia, an inheritable disorder characterized by muscle stiffness and renal salt wasting. CLC-2 is highly expressed in the epithelia of several organs including lung, which suggests CLC-2 may be a possible therapeutic target for cystic fibrosis. CLC-3 expression is particularly abundant in neuronal tissue, while CLC-4 expression is evident in skeletal and cardiac muscle as well as brain. Mutations in the gene encoding CLC-5 lead to Dent’s disease, a renal disorder characterized by proteinuria and hypercalciuria. CLC-6 and CLC-7 are broadly expressed in several tissues including testes, kidney, brain and muscle.

General readings

Tran,P., et al., (2002) Mamm. Genome 13 (9), 483-492

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CLCN6 antibody

  Rabbit Polyclonal Anti-CLCN6 Antibody  
Lanes: 1. Human NT-2 cells (60ug) lysate 2. Mouse WT brain extract (80ug); Primary Antibody Dilution: 2 ug/ml; Secondary Antibody: IRDye 800CW goat anti-rabbit from Li-COR Bioscience; Secondary Antibody Dilution: ; 1: 20,000; Gene Name: ; CLCN6; Submitted Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CLCN6 antibody

Western blot (WB) analysis of CLC-6 antibody (Cat.-No.: AP01392PU-N) in extracts from HT-29 cells. Rabbit Aff - Purified Hu, Ms WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CLCN6 antibody

CLCN6 Mouse IgG2b 2H2 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CLCN6 antibody

Western blot analysis of extracts from COS7/HT-29 cells, using CLCN6 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
50 µg / €230.00
  Assay Biotech

CLCN6 antibody

Western blot analysis of extracts from COS7/HT-29 cells, using CLCN6 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
0.1 mg / €330.00
  Assay Biotech

CLCN6 antibody

Human NT-2, Mouse WT brain; . Lanes: 1. Human NT-2 cells (60ug) lysate 2. Mouse WT brain extract (80ug). Primary Antibody Dilution: 2ug/ml. Secondary Antibody: IRDye 800CW goat anti-rabbit from Li-COR Bioscience. Secondary Antibody Dilution: 1: 20,000. Gene Name: CLCN6. Submitted by: Dr. Yuzhi Chen, University of Arkansas for Medical Science.; CLCN6 antibody - C-terminal region (ARP35334_T100) in Human NT-2, Mouse WT brain cells using Western Blot Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Rb, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

CLCN6 antibody

Western blot analysis of CLCN6 expression in HEK293A (A); Jurkat (B) whole cell lysates. Rabbit Aff - Purified Hu, Rb WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

CLCN6 antibody

Western blot analysis of CLCN6 expression in HEK293A (A); Jurkat (B) whole cell lysates. Rabbit Aff - Purified Hu, Rb WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

CLCN6 antibody

Western blot analysis of CLCN6 expression in HEK293A (A); Jurkat (B) whole cell lysates. Rabbit Aff - Purified Hu, Rb WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

CRISPR

Catalog No. Species Donor Vector  

CLCN6 - human gene knockout kit via CRISPR

CLCN6 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

CLCN6 - human gene knockout kit via CRISPR

CLCN6 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CLCN6 - human gene knockout kit via CRISPR

CLCN6 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CLCN6 - human gene knockout kit via CRISPR

CLCN6 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Clcn6 - mouse gene knockout kit via CRISPR

Clcn6 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Clcn6 - mouse gene knockout kit via CRISPR

Clcn6 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Clcn6 - mouse gene knockout kit via CRISPR

Clcn6 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Clcn6 - mouse gene knockout kit via CRISPR

Clcn6 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CLCN6

CLCN6 Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

CLCN6

CLCN6 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

CLCN6

CLCN6 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

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