CLEC4A antibody

Principal name

CLEC4A antibody

Alternative names for CLEC4A antibody

C-type lectin DDB27, CLECSF6, DCIR, LLIR, HDCGC13P, Dendritic cell immunoreceptor, Lectin-like immunoreceptor, C-type lectin domain family 4 member A, C-type lectin superfamily member 6

SwissProt ID

Q67EQ0 (Rat), Q9QZ15 (Mouse), Q9UMR7 (Human)

Gene ID

50856 (CLEC4A)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Flow Cytometry (F), Immunoprecipitation (IP), Enzyme Immunoassay (E)

Background of CLEC4A antibody

DCIR (dendritic cell immunoreceptor), also known as LLIR, DDB27, CLECSF6, HDCGC13P, is a member of the Dectin-2 family of C-type lectins. DCIR is expressed as a type II membrane glycoprotein of 237 aa with a single carbohydrate recognition domain (CRD), closest in homology to those of the macrophage lectin and hepatic asialoglycoprotein receptors. In contrast to the other members of this family, the intracellular domain of DCIR contains a consensus immunoreceptor tyrosine-based inhibitory motif (ITIM). DCIR is expressed on dendritic cells, monocytes, macrophages, B lymphocytes, neutrophils, granulocytes and plasmacytoid dendritic cells, but not detected on NK and T cells. In vitro, DCIR is strongly expressed by DCs derived from blood monocytes cultured with GM-CSF and IL-4 with a higher expression in CD14+ than CD1a+ derived DC. Finally, DCIR expression is down-regulated by signals inducing DC maturation such as CD40 ligand, LPS, or TNF-. Thus, DCIR is differentially expressed on DCs depending on their origin and stage of maturation/activation. DCIR represents a novel surface molecule expressed by antigenpresenting cells, and of potential importance in regulation of DC function.
(Bates EE et al, 1999; J. Immunol., 163: 1973-1983).

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CLEC4A antibody

IHC staining of human tonsil frozen section with clone 111F8 (DX0180) Mouse IgG1 111F8.04 Alexa Fluor 488 Hu C, F, ICC/IF, WB
50 µg / €390.00
  Dendritics SAS

CLEC4A antibody

IHC staining of human tonsil frozen section with clone 111F8 (DX0180) Mouse IgG1 111F8.04 Alexa Fluor 488 Hu C, F, ICC/IF, WB
0.1 mg / €520.00
  Dendritics SAS

CLEC4A antibody

IHC staining of human tonsil frozen section with clone 111F8 (DX0180) Mouse IgG1 111F8.04 Alexa Fluor 546 Hu F, ICC/IF
50 µg / €390.00
  Dendritics SAS

CLEC4A antibody

IHC staining of human tonsil frozen section with clone 111F8 (DX0180) Mouse IgG1 111F8.04 Alexa Fluor 546 Hu ICC/IF, WB
0.1 mg / €520.00
  Dendritics SAS

CLEC4A antibody

IHC staining of human tonsil frozen section with clone 111F8 (DX0180) Mouse IgG1 111F8.04 Alexa Fluor 647 Hu F, WB
50 µg / €390.00
  Dendritics SAS

CLEC4A antibody

IHC staining of human tonsil frozen section with clone 111F8 (DX0180) Mouse IgG1 111F8.04 Alexa Fluor 647 Hu F, WB
0.1 mg / €520.00
  Dendritics SAS

CLEC4A antibody

IHC staining of human tonsil frozen section with clone 111F8 (DX0180) Mouse IgG1 111F8.04 Biotin Hu C, WB
50 µg / €360.00
  Dendritics SAS

CLEC4A antibody

IHC staining of human tonsil frozen section with clone 111F8 (DX0180) Mouse IgG1 111F8.04 Biotin Hu C, WB
0.1 mg / €480.00
  Dendritics SAS

CLEC4A antibody

IHC staining of human tonsil frozen section with clone 111F8 (DX0180) Mouse IgG1 111F8.04 Purified Hu C, F, IP, WB
50 µg / €330.00
  Dendritics SAS

CLEC4A antibody

IHC staining of human tonsil frozen section with clone 111F8 (DX0180) Mouse IgG1 111F8.04 Purified Hu C, F, IP, WB
0.1 mg / €440.00
  Dendritics SAS

CLEC4A antibody

Western blot analysis of Mouse liver tissue using TA321848(CLEC4A Antibody) at dilution 1/100 Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CLEC4A antibody

Predicted band size: 28 kDa . Positive control: RAW264.7, Hela, 823 and A549 cell lysate. Recommended dilution: 1/200-1000. (Gel: 15+12%SDS-PAGE Lane1:RAW264.7 cell lysate Lane2:Hela cell lysate Lane3:823 cell lysate Lane4:A549 cell lysate Lysates: 40 ug per lane Primary antibody: 1/300 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 10 minutes) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CLEC4A antibody

Western Blot analysis of CLEC4A expression in transfected 293T cell line (H00050856-T01) by CLEC4A MaxPab polyclonal antibody.

Lane 1: CLEC4A transfected lysate(26.07 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

CLEC4A antibody

Western Blot analysis of CLEC4A expression in transfected 293T cell line (H00050856-T01) by CLEC4A MaxPab polyclonal antibody.

Lane 1: CLEC4A transfected lysate(26.07 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

CLEC4A antibody

Immunohistochemistry-Paraffin: CLEC4A Antibody [NBP1-84446] Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in glandular cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CLEC4A

CLEC4A Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

CLEC4A

CLEC4A Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

CLEC4A 293T Cell Transient Overexpression Lysate(Denatured)

CLEC4A 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

CLEC4A overexpression lysate

CLEC4A overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

CLEC4A overexpression lysate

CLEC4A overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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