CLIP1 / Restin antibody

Principal name

CLIP1 / Restin antibody

Alternative names for CLIP1 / Restin antibody

CYLN1, RSN, CLIP-170, CAP-Gly domain-containing linker protein 1, Cytoplasmic linker protein 170 alpha-2, Reed-Sternberg intermediate filament-associated protein, Cytoplasmic linker protein 1

SwissProt ID

O42184 (Chick), P30622 (Human), P30622-1, Q922J3 (Mouse)

Gene ID

6249 (CLIP1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bt (Bat), Bov (Bovine), Can (Canine), Chk (Chicken), Eq (Equine), Hst (Hamster), Mky (Monkey), Op (Opossum), Por (Porcine), Prim (Primate), Rb (Rabbit), Tr (Turkey), Bear

Available hosts

Rabbit, Goat

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of CLIP1 / Restin antibody

Cytoplasmic linker protein of 170 kDa (CLIP-170) is the original member of a group of microtuble binding proteins designated as plus-end-binding proteins(+TIPs). CLIP-170 binds to the growing plus ends of microtubules and acts as a linker between the dynamic microtubule ends and organelle membranes. The protein acts as an anticatastrophic factor, promoting microtubule rescue near the cell periphery. Fluorescently labeled CLIP-170 can be visualized as a comet like streak around the growing ends of microtubules. CLIP-170 colocalizes with dynactin and dynein at microtubule ends and also at the kinetochore. Restin, first identified as a marker for Hodgkin and Reed-Sternberg (HRS) cells, is a 160 kDa splice variant of the gene that includes a 35 amino acid stretch not present in CLIP-170. CLIP-170/restin is highly expressed in HRS cells, monocyte-derived dendritic cells, IL-4 + CD40L activated B cells, and in Ki-1 lymphoma.

General readings

Tanenbaum ME, Macurek L, Galjart N, Medema RH.
Dynein, Lis1 and CLIP-170 counteract Eg5-dependent centrosome separation during bipolar spindle assembly.
The EMBO journal 2008 Dec 27 (24): 3235-45.

16 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CLIP1 / Restin (C-term) antibody

  Goat Anti-Restin / CLIP1 Antibody  
TA305928 (1ug/ml) staining of Human Breast Cancer lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Can, Hu, Ms, Por, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CLIP1 / Restin antibody

  Rabbit Polyclonal CLIP170 Antibody  
Western blot analysis of CLIP170 in rat brain tissue lysate with CLIP170 antibody at (A) 0.5 and (B) 1 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CLIP1 / Restin antibody

  Rabbit polyclonal anti-CLIP1 antibody  
Western blot analysis of extracts from MCF-7 cells, RAW264.7 cells, HepG2 cells, COLO cells and HUVEC cells, using CLIP1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CLIP1 / Restin antibody

  Rabbit Polyclonal Anti-CLIP1 Antibody  
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using (CLIP1 Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200) Rabbit IgG Purified Hu, Ms E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CLIP1 / Restin antibody

Western blot (WB) analysis of CLIP-170 antibody (Cat.-No.: AP01464PU-N) in extracts from HUVEC cell Rabbit Aff - Purified Hu, Ms WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CLIP1 / Restin (1404-1417) antibody

Human Thyroid (formalin-fixed, paraffin-embedded) stained with CLIP1 antibody AP22587PU-N followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen. Goat Aff - Purified Bear, Bov, Bt, Can, Chk, Elephant, Eq, Hst, Hu, Mky, Ms, Op, Por, Prim, Rb, Rt, Tr E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CLIP1 / Restin antibody

Western blot analysis of extracts from HuvEc/COLO/MCF-7/HepG2/RAW264.7 cells, using CLIP1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
50 µg / €230.00
  Assay Biotech

CLIP1 / Restin antibody

Western blot analysis of extracts from HuvEc/COLO/MCF-7/HepG2/RAW264.7 cells, using CLIP1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

CLIP1 - human gene knockout kit via CRISPR

CLIP1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

CLIP1 - human gene knockout kit via CRISPR

CLIP1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CLIP1 - human gene knockout kit via CRISPR

CLIP1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CLIP1 - human gene knockout kit via CRISPR

CLIP1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, CLIP1 (mGFP-tagged)-Human CAP-GLY domain containing linker protein 1 (CLIP1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, CLIP1 (mGFP-tagged)-Human CAP-GLY domain containing linker protein 1 (CLIP1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €2,530.00
  OriGene Technologies, Inc.

Lenti ORF particles, CLIP1 (mGFP-tagged)-Human CAP-GLY domain containing linker protein 1 (CLIP1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, CLIP1 (mGFP-tagged)-Human CAP-GLY domain containing linker protein 1 (CLIP1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,320.00
  OriGene Technologies, Inc.

Lenti ORF particles, CLIP1 (Myc-DDK-tagged)-Human CAP-GLY domain containing linker protein 1 (CLIP1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, CLIP1 (Myc-DDK-tagged)-Human CAP-GLY domain containing linker protein 1 (CLIP1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €2,280.00
  OriGene Technologies, Inc.

Lenti ORF particles, CLIP1 (Myc-DDK-tagged)-Human CAP-GLY domain containing linker protein 1 (CLIP1), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, CLIP1 (Myc-DDK-tagged)-Human CAP-GLY domain containing linker protein 1 (CLIP1), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,180.00
  OriGene Technologies, Inc.

16 Item(s)

per page
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