CLIP1 / Restin antibody

Principal name

CLIP1 / Restin antibody

Alternative names for CLIP1 / Restin antibody

CYLN1, RSN, CLIP-170, CAP-Gly domain-containing linker protein 1, Cytoplasmic linker protein 170 alpha-2, Reed-Sternberg intermediate filament-associated protein, Cytoplasmic linker protein 1

SwissProt ID

O42184 (Chick), P30622 (Human), P30622-1, Q922J3 (Mouse)

Gene ID

6249 (CLIP1), 8624976 (abcC9)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Can (Canine), Por (Porcine)

Available hosts

Rabbit, Goat

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Paraffin Sections (P), ChIP assay (ChIP), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Immunoprecipitation (IP)

Background of CLIP1 / Restin antibody

Cytoplasmic linker protein of 170 kDa (CLIP-170) is the original member of a group of microtuble binding proteins designated as plus-end-binding proteins(+TIPs). CLIP-170 binds to the growing plus ends of microtubules and acts as a linker between the dynamic microtubule ends and organelle membranes. The protein acts as an anticatastrophic factor, promoting microtubule rescue near the cell periphery. Fluorescently labeled CLIP-170 can be visualized as a comet like streak around the growing ends of microtubules. CLIP-170 colocalizes with dynactin and dynein at microtubule ends and also at the kinetochore. Restin, first identified as a marker for Hodgkin and Reed-Sternberg (HRS) cells, is a 160 kDa splice variant of the gene that includes a 35 amino acid stretch not present in CLIP-170. CLIP-170/restin is highly expressed in HRS cells, monocyte-derived dendritic cells, IL-4 + CD40L activated B cells, and in Ki-1 lymphoma.

General readings

Tanenbaum ME, Macurek L, Galjart N, Medema RH.
Dynein, Lis1 and CLIP-170 counteract Eg5-dependent centrosome separation during bipolar spindle assembly.
The EMBO journal 2008 Dec 27 (24): 3235-45.

17 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CLIP1 / Restin (C-term) antibody

TA305928 (1ug/ml) staining of Human Breast Cancer lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Can, Hu, Ms, Por, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CLIP1 / Restin antibody

Western blot analysis of CLIP170 in rat brain tissue lysate with CLIP170 antibody at (A) 0.5 and (B) 1 ug/mL. Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CLIP1 / Restin antibody

Western blot analysis of extracts from MCF-7 cells, RAW264.7 cells, HepG2 cells, COLO cells and HUVEC cells, using CLIP1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CLIP1 / Restin antibody

Western blot (WB) analysis of CLIP-170 antibody (Cat.-No.: AP01464PU-N) in extracts from HUVEC cell Rabbit Aff - Purified Hu, Ms WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CLIP1 / Restin (1404-1417) antibody

Human Thyroid (formalin-fixed, paraffin-embedded) stained with CLIP1 antibody AP22587PU-N followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen. Goat Aff - Purified Bear, Bov, Bt, Can, Chk, Elephant, Eq, Hst, Hu, Mky, Ms, Op, Por, Prim, Rb, Rt, Tr E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CLIP1 / Restin Control Peptide

CLIP1 / Restin
50 µg / €160.00
  Acris Antibodies GmbH

CLIP1 / Restin antibody

Western blot analysis of CLIP1 in rat brain tissue lysate with CLIP1 polyclonal antibody ( Cat # PAB13046 ) at ( A ) 0.5 and ( B ) 1 µg/ml. Rabbit Hu, Ms, Rt WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

CLIP1 / Restin antibody

Western blot analysis of extracts from HuvEc/COLO/MCF-7/HepG2/RAW264.7 cells, using CLIP1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
50 µg / €205.00
  Assay Biotech

CLIP1 / Restin antibody

Western blot analysis of extracts from HuvEc/COLO/MCF-7/HepG2/RAW264.7 cells, using CLIP1 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, WB
0.1 mg / €310.00
  Assay Biotech

CLIP1 / Restin (C-term) antibody

Human Fetal liver; WB Suggested Anti-CLIP1 Antibody. . Titration: 0.125 ug/ml. . Positive Control: Fetal Liver; CLIP1 antibody - C-terminal region (ARP61766_P050) in Human Fetal liver cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

CLIP1 / Restin antibody

Western blot analysis of CLIP1 expression in KNRK (A); HeLa (B); HepG2 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt IP, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

CLIP1 / Restin antibody

Western blot analysis of CLIP1 expression in KNRK (A); HeLa (B); HepG2 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt IP, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

CLIP1 / Restin antibody

Western blot analysis of CLIP1 expression in KNRK (A); HeLa (B); HepG2 (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt IP, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

CLIP1 / Restin antibody

Western Blot: CLIP-170 Antibody [NBP1-00758] - Western blot (WB) analysis of CLIP-170 (K1332)   antibody in extracts from HUVEC cell Rabbit Aff - Purified Hu, Ms WB
0.1 mg / €420.00
  Novus Biologicals Inc.

CLIP1 / Restin antibody

Immunohistochemistry-Paraffin: CLIP170 Antibody [NBP1-36749] - (2.5µg/ml) staining of paraffin embedded Human Thyroid Gland. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. Goat Hu ChIP, E, P, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

CLIP1 / Restin antibody

Immunofluorescence: CLIP170 Antibody [NBP1-76921] - Human brain tissue with CLIP170 antibody at 20 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

CLIP1 / Restin antibody

Immunohistochemistry-Paraffin: CLIP170 Antibody [NBP1-85568] - staining of human placenta shows strong cytoplasmic positivity in trophoblastic cells. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

17 Item(s)

per page
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