CNGA2 antibody

Principal name

CNGA2 antibody

Alternative names for CNGA2 antibody

CNG channel alpha-2, CNCA, CNCA1, CNCG2, CNG2, Cyclic nucleotide-gated olfactory channel, Cyclic nucleotide-gated cation channel 2

SwissProt ID

Q00195 (Rat), Q03041 (Bovin), Q16280 (Human), Q28718 (Rabit), Q62398 (Mouse)

Gene ID

1260 (CNGA2), 25411 (Cnga2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E)

Background of CNGA2 antibody

Cyclic nucleotides are important second messengers in many cellular functions such as visual transduction, and relaxation of smooth muscle cells. Cyclic nucleotides exert their cellular functions through three major classes of cellular receptors, one of them is the cyclic nucleotide-gated (CNG) channels. The CNG channels are non-selective cation channels facilitating the influx of + and Ca2+ ions, following activation by intracellular cyclic nucleotides. In vertebrates, six members of the CNG channel family were identified and grouped according to sequence homology into two subtypes, CNGA and CNGB. To date, four types of the a subunits (CNGA1-4) and two b subunits (CNGB1, CNGB3) have been characterized. tive CNG channels are composed of a and b subunits in a tetrameric configuration. Each subunit contains 6 TM domains and intracellular cAMP or cGMP binding domains, but are also modulated by other factors including phosphorylation and calmodulin. In a heterologous expression system, only the a subunits are capable of forming functiol homomeric channels. CNG ion channels are essential in visual and olfactory sigl transduction. CNG channels were origilly detected in rod and cone photoreceptors and olfactory receptor cells, where they mediate the transduction of exterl sensory stimuli into neurol activity. CNGA2 is predomintly expressed in olfactory neurons (the olfactory type receptor). However, electrophysiological and molecular data indicate that CNGA1, and especially CNGA2, are widely distributed and functiolly active in many regions of the brain, including the hippocampus, cerebral cortex, cerebellum, and brainstem.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CNGA2 antibody

Western blot analysis of rat brain membranes: 1. Anti-CNGA2 antibody , (1:200). 2. Anti-CNGA2 antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

CNGA2 antibody

Sample (30 ug of whole cell lysate). A: 293T. B: A431 . C: Hep G2 . 7.5% SDS PAGE. TA308175 diluted at 1:1000. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CNGA2 antibody

Immunofluorescence analysis of A549 cells, using CNGA2 antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, ICC/IF
0.1 ml / €325.00
  OriGene Technologies, Inc.

CNGA2 antibody

Predicted cell location: Cytoplasm, Cell membrane. Positive control: Human cervical and liver cancer tissue. Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded Human cervical and liver cancer tissue using CNGA2 antibody at dilution 1/25, on the right is treated with the fusion protein. (Original magnification: x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CNGA2 antibody

Gel: 10%SDS-PAGE, Lysate: 30 µg, Lane: 293T cells, Primary antibody:CNGA2 Antibody at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CNGA2 antibody

Immunofluorescence analysis of A549 cells, using CNGA2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF
50 µg / €205.00
  Assay Biotech

CNGA2 antibody

Immunofluorescence analysis of A549 cells, using CNGA2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF
0.1 mg / €310.00
  Assay Biotech

CNGA2 antibody

Western blot analysis of CNGA2 expression in HepG2 (A); A431 (B) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

CNGA2 antibody

Western blot analysis of CNGA2 expression in HepG2 (A); A431 (B) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

CNGA2 antibody

Western blot analysis of CNGA2 expression in HepG2 (A); A431 (B) whole cell lysates. Rabbit Aff - Purified Hu, Ms, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

CNGA2 antibody

CNGA2 Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF
0.1 mg / €360.00
  Novus Biologicals Inc.

CNGA2 antibody

CNGA2 Rabbit IgG Aff - Purified Hu, Ms, Rt E, ICC/IF
50 µg / €290.00
  Novus Biologicals Inc.

CNGA2 antibody

Immunohistochemistry-Paraffin: CNGA2 Antibody [NBP1-85527] - Immunohistochemical staining of human cerebral cortex shows moderate cytoplasmic positivity in neuronal cells. Rabbit IgG Aff - Purified Hu P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

13 Item(s)

per page
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