CNGA2 antibody

Principal name

CNGA2 antibody

Alternative names for CNGA2 antibody

CNG channel alpha-2, CNCA, CNCA1, CNCG2, CNG2, Cyclic nucleotide-gated olfactory channel, Cyclic nucleotide-gated cation channel 2

SwissProt ID

Q00195 (Rat), Q03041 (Bovin), Q16280 (Human), Q28718 (Rabit), Q62398 (Mouse)

Gene ID

1260 (CNGA2), 25411 (Cnga2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of CNGA2 antibody

Cyclic nucleotides are important second messengers in many cellular functions such as visual transduction, and relaxation of smooth muscle cells. Cyclic nucleotides exert their cellular functions through three major classes of cellular receptors, one of them is the cyclic nucleotide-gated (CNG) channels. The CNG channels are non-selective cation channels facilitating the influx of + and Ca2+ ions, following activation by intracellular cyclic nucleotides. In vertebrates, six members of the CNG channel family were identified and grouped according to sequence homology into two subtypes, CNGA and CNGB. To date, four types of the a subunits (CNGA1-4) and two b subunits (CNGB1, CNGB3) have been characterized. tive CNG channels are composed of a and b subunits in a tetrameric configuration. Each subunit contains 6 TM domains and intracellular cAMP or cGMP binding domains, but are also modulated by other factors including phosphorylation and calmodulin. In a heterologous expression system, only the a subunits are capable of forming functiol homomeric channels. CNG ion channels are essential in visual and olfactory sigl transduction. CNG channels were origilly detected in rod and cone photoreceptors and olfactory receptor cells, where they mediate the transduction of exterl sensory stimuli into neurol activity. CNGA2 is predomintly expressed in olfactory neurons (the olfactory type receptor). However, electrophysiological and molecular data indicate that CNGA1, and especially CNGA2, are widely distributed and functiolly active in many regions of the brain, including the hippocampus, cerebral cortex, cerebellum, and brainstem.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CNGA2 antibody

  Rabbit polyclonal Anti-CNGA2  
Western blot analysis of rat brain membranes: 1. Anti-CNGA2 antibody , (1:200). 2. Anti-CNGA2 antibody, preincubated with the control peptide antigen. Rabbit Purified Ms, Rt WB
0.2 ml / €435.00
  OriGene Technologies, Inc.

CNGA2 antibody

  Rabbit Polyclonal antibody to CNGA2 (cyclic nucleotide gated channel alpha 2)  
Sample (30 ug of whole cell lysate). A: 293T. B: A431 . C: Hep G2 . 7.5% SDS PAGE. TA308175 diluted at 1:1000. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CNGA2 antibody

  Rabbit polyclonal anti-CNGA2 antibody  
Immunofluorescence analysis of A549 cells, using CNGA2 antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, ICC/IF
0.1 ml / €325.00
  OriGene Technologies, Inc.

CNGA2 antibody

  Anti-CNGA2 Rabbit Polyclonal Antibody  
Predicted cell location: Cytoplasm, Cell membrane. Positive control: Human cervical and liver cancer tissue. Recommended dilution: 1/50-200  The image on the left is immunohistochemistry of paraffin-embedded Human cervical and liver cancer tissue using CNGA2 antibody at dilution 1/25, on the right is treated with the fusion protein. (Original magnification: x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CNGA2 antibody

  Anti-CNGA2 Rabbit Polyclonal Antibody  
Gel: 10%SDS-PAGE, Lysate: 30 µg, Lane: 293T cells, Primary antibody:CNGA2 Antibody at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 30 seconds Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CNGA2 antibody

Immunofluorescence analysis of A549 cells, using CNGA2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF
50 µg / €230.00
  Assay Biotech

CNGA2 antibody

Immunofluorescence analysis of A549 cells, using CNGA2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

CNGA2 - human gene knockout kit via CRISPR

CNGA2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

CNGA2 - human gene knockout kit via CRISPR

CNGA2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CNGA2 - human gene knockout kit via CRISPR

CNGA2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CNGA2 - human gene knockout kit via CRISPR

CNGA2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, CNGA2 (mGFP-tagged)-Human cyclic nucleotide gated channel alpha 2 (CNGA2), 200 uL, >10^7 TU/mL

Lenti ORF particles, CNGA2 (mGFP-tagged)-Human cyclic nucleotide gated channel alpha 2 (CNGA2), 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, CNGA2 (Myc-DDK-tagged)-Human cyclic nucleotide gated channel alpha 2 (CNGA2), 200 uL, >10^7 TU/mL

Lenti ORF particles, CNGA2 (Myc-DDK-tagged)-Human cyclic nucleotide gated channel alpha 2 (CNGA2), 200 uL, >10^7 TU/mL  
200 µl / €940.00
  OriGene Technologies, Inc.

Rat Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Cnga2 (GFP-tagged ORF) - Rat cyclic nucleotide gated channel alpha 2 (Cnga2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Cnga2 (GFP-tagged ORF) - Rat cyclic nucleotide gated channel alpha 2 (Cnga2), 200 uL, >10^7 TU/mL  
200 µl / €1,330.00
  OriGene Technologies, Inc.

Lenti ORF particles, Cnga2 (Myc-DDK-tagged ORF) - Rat cyclic nucleotide gated channel alpha 2 (Cnga2), 200 uL, >10^7 TU/mL

Lenti ORF particles, Cnga2 (Myc-DDK-tagged ORF) - Rat cyclic nucleotide gated channel alpha 2 (Cnga2), 200 uL, >10^7 TU/mL  
200 µl / €1,198.00
  OriGene Technologies, Inc.

15 Item(s)

per page
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