Coagulation factor VII (F7) antibody

Principal name

Coagulation factor VII (F7) antibody

Alternative names for Coagulation factor VII (F7) antibody

Proconvertin, SPCA, Serum prothrombin conversion accelerator

SwissProt ID

P08709 (Human), P22457 (Bovin), P70375 (Mouse), P98139 (Rabit), Q8K3U6 (Rat)

Gene ID

2155 (F7), 14068

Available reactivities

Hu (Human), Prim (Primate), Ms (Mouse), Mky (Monkey), Rt (Rat), Can (Canine), Rb (Rabbit), Bov (Bovine), Eq (Equine), Por (Porcine)

Available hosts

Mouse, Rabbit, Chicken, Sheep, Rat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Radioimmunoassay (R), ELISA (detection) (E(detection)), Paraffin Sections (P), Immunoprecipitation (IP), Neutralisation (NEUT), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Immunodiffusion (ID)

Background of Coagulation factor VII (F7) antibody

Plasma factor VII is ea vitamin K-dependent glycoprotein (MW 63,000) with an electrophoresis mobility in the beta region. It circulates in plasma in a semi-active form, even in the absence of tissue factor. Then procoagulant activity of FVII can be destroyed by heating to 56ºC. It is unstable below pH 3 and above pH 9. It survives he clotting process and its presence can be demonstrated in serum. After isolation its molecular weight was 44,700. Factor VII is a serine protease depending on a lipid cofactor and can be activated to FVIIa by factors IXa, Xa and XIIIa, thereby linking the intrinsic and extrinsic coagulation systems since FXII and FIX can be activated by kallikrein. The normal adult plasma FVII level is about 0.5 to 1.0 mg/ml. In normal newborn infants the average level is about 50% of the adult concentration. A deficiency of FVII, congenital or acquired, results in a bleeding disorder. The congenital form is rare but the acquired form is commonly seen in association with a deficiency of FII, FIX and FX in liver disease and in patients taking coumarin-type anticoagulant drugs. Both procoagulant activity and FVII-related antigen are depressed. In haemorrhagic disease of the newborn, procoagulant activity is reduced but not the level of the FVII antigen. A similar discrepancy may be seen in congenital deficiencies but in other types FVII antigen will be severely reduced as a result of genetic suppression of synthesis capacity. If still present, the FVII molecules appear to be biologically defective. Heterozygote carriers can now be detected. FVII procoagulant activity and related antigen levels have been shown to correlate directly with the plasma triglyceride concentration. This makes FVII a risk factor for myocardial infarction; immediately following an acute myocardial infarction patients have increased plasma FVII procoagulant activity.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Coagulation factor VII (F7) antibody

Sample(30 ug of whole cell lysate). A:H1299. 7.5% SDS PAGE. TA308874 diluted at 1:500 Rabbit IgG Aff - Purified Hu, Ms P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Coagulation factor VII (F7) antibody

Western blot analysis of extracts from Jurkat cells, treated with eto (25uM, 24hours), using FA7 (light chain, Cleaved-Arg212) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Coagulation factor VII (F7) antibody

Predicted cell location: Cytoplasm. Positive control: Human thyroid and lung cancer tissue. Recommended dilution: 1/15-50  The image on the left is immunohistochemistry of paraffin-embedded human thyroid cancer tissue using F7 antibody at dilution 1/30, on the right is treated with the fusion protein. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Coagulation factor VII (F7) antibody

Predicted band size: 49 kDa . Positive control: NIH/3T3, 293T and Jurkat cell lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lane1: NIH/3T3 cell lysate Lane2: 293T cell lysate Lane3: Jurkat cell lysate Lysates: 40 ug per lane Primary antibody: 1/400 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 30 seconds) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Coagulation factor VII (F7) antibody

WB Suggested Anti-F7 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Human heart Rabbit IgG Purified Can, Hu, Ms, Rb WB
50 µg / €325.00
  OriGene Technologies, Inc.

Coagulation factor VII (F7) antibody

WB Suggested Anti-F7 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Bov, Eq, Hu, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Coagulation factor VII (F7) antibody

Coagulation factor VII (F7) Mouse IgG1 RFFVII/2 Aff - Purified Hu E, R, WB
0.5 mg / €550.00
  Acris Antibodies GmbH

Coagulation factor VII (F7) (+VIIa) antibody

Coagulation factor VII (F7) Mouse IgG1 CaFVII-22 Biotin Hu E, WB
0.1 mg / €370.00
  Acris Antibodies GmbH

Coagulation factor VII (F7) (+VIIa) antibody

Coagulation factor VII (F7) Mouse IgG1 CaFVII-22 Purified Hu E, WB
0.2 mg / €450.00
  Acris Antibodies GmbH

Coagulation factor VII (F7) (+VIIa) antibody

Coagulation factor VII (F7) Mouse IgG1 AA-3 Biotin Hu E, WB
0.1 mg / €370.00
  Acris Antibodies GmbH

Coagulation factor VII (F7) (+VIIa) antibody

Coagulation factor VII (F7) Mouse IgG1 AA-3 Purified Hu E, WB
0.2 mg / €450.00
  Acris Antibodies GmbH

Coagulation factor VII (F7) (+VIIa) antibody

Coagulation factor VII (F7) Mouse IgG1 AD-1 Biotin Hu E, WB
0.1 mg / €370.00
  Acris Antibodies GmbH

Coagulation factor VII (F7) (+VIIa) antibody

Coagulation factor VII (F7) Mouse IgG1 AD-1 Purified Hu E, WB
0.2 mg / €450.00
  Acris Antibodies GmbH

Coagulation factor VII (F7) antibody

Human Liver (formalin-fixed, paraffin-embedded) stained with F7 antibody AP22826PU-N at 5 µg/ml followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen. Sheep IgG Ig Fraction Hu E, IP, NEUT, P
50 µg / €470.00
  Acris Antibodies GmbH

Coagulation factor VII (F7) (209-444) antibody

Human Lung: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Aff - Purified Hu, Mky, Ms P, WB
50 µl / €470.00
  Acris Antibodies GmbH

Coagulation factor VII (F7) antibody

Coagulation factor VII (F7) Rabbit Serum Hu ID, IP
1 ml / €430.00
  Acris Antibodies GmbH

Coagulation factor VII (F7) antibody

Coagulation factor VII (F7) Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Coagulation factor VII (F7) antibody

F7 MaxPab rabbit polyclonal antibody. Western Blot analysis of F7 expression in A-431. Rabbit Serum Hu E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

Coagulation factor VII (F7) antibody

Proximity Ligation Analysis (PLA) of protein-protein interactions between F7 and F3. HeLa cells were stained with anti-F7 rabbit purified polyclonal 1:1200 and anti-F3 mouse monoclonal antibody 1:50. Signals were detected by Duolink® 30 Detection Kit 613(red), and nuclei were counterstained with DAPI (blue). Each red dot represents the detection of protein-protein interaction complex. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Coagulation factor VII (F7) antibody

Coagulation factor VII (F7) Mouse IgG1 Hu E, R, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

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