Coagulation factor X (F10) antibody

Principal name

Coagulation factor X (F10) antibody

Alternative names for Coagulation factor X (F10) antibody

Stuart factor, Stuart-Prower factor

SwissProt ID

O19045 (Rabit), O88947 (Mouse), P00742 (Human), P00743 (Bovin), P25155 (Chick), Q63207 (Rat)

Gene ID

2159 (F10), 14058

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Por (Porcine), Rb (Rabbit), Rt (Rat)

Available hosts

Mouse, Rat, Sheep, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Radioimmunoassay (R), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Immunoelectrophoresis (Ie), Immunodiffusion (ID)

Background of Coagulation factor X (F10) antibody

F10 is the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting.This gene encodes the vitamin K-dependent coagulation factor X of the blood coagulation cascade. This factor undergoes multiple processing steps before its preproprotein is converted to a mature two-chain form by the excision of the tripeptide RKR. Two chains of the factor are held together by 1 or more disulfide bonds; the light chain contains 2 EGF-like domains, while the heavy chain contains the catalytic domain which is structurally homologous to those of the other hemostatic serine proteases. The mature factor is activated by the cleavage of the activation peptide by factor IXa (in the intrisic pathway), or by factor VIIa (in the extrinsic pathway). The activated factor then converts prothrombin to thrombin in the presence of factor Va, Ca+2, and phospholipid during blood clotting. Mutations of this gene result in factor X deficiency, a hemorrhagic condition of variable severity. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Hsu,H.J., (2008) J. Biol. Chem. 283 (18), 12343-12353

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Coagulation factor X (F10) antibody

Factor X antibody detects F10 protein by Western blot analysis. A. 30 ug 293T whole cell lysate/extract. B. 30 ug whole cell lysate/extract of human F10-transfected 293T cells. 10 % SDS-PAGE. Factor X antibody (TA308876) dilution: 1:5000 Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Coagulation factor X (F10) antibody

Western blot analysis of extracts from rat liver cells, using FA10 (activated heavy chain, Cleaved-Ile235) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Coagulation factor X (F10) antibody

Western blot analysis of extracts from A549 cells, treated with etoposide (24uM, 24hours), using FA10 (light chain, Cleaved-Ala41) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Coagulation factor X (F10) antibody

Predicted band size: 55 kDa . Positive control: A549 cell lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/400 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 10 minutes) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Coagulation factor X (F10) antibody

Predicted band size: 55 kDa . Positive control: A431 cell lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/200 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 10 seconds) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Coagulation factor X (F10) antibody

Western blot analysis of extracts of HepG2 cell lines, using F10 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Coagulation factor X (F10) antibody

Coagulation factor X (F10) Mouse IgG1 F10-1 Aff - Purified Hu E
0.5 mg / €440.00
  Acris Antibodies GmbH

Coagulation factor X (F10) (+Xa) (Calcium Dependent) antibody

Coagulation factor X (F10) Mouse IgG1 CaFX-50 Biotin Hu E, WB
0.1 mg / €370.00
  Acris Antibodies GmbH

Coagulation factor X (F10) (+Xa) (Calcium Dependent) antibody

Coagulation factor X (F10) Mouse IgG1 CaFX-50 Purified Hu E, WB
0.2 mg / €450.00
  Acris Antibodies GmbH

Coagulation factor X (F10) (C-term) antibody

Western blot analysis of F10 antibody (C-term) (AP17353PU-N) in 293 cell line lysates (35 µg/lane). F10 (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Coagulation factor X (F10) antibody

Liver, vessel: Formalin-Fixed, Paraffin-Embedded (FFPE) Sheep IgG Aff - Purified Hu E, ID, Ie, P
50 µg / €470.00
  Acris Antibodies GmbH

Coagulation factor X (F10) antibody

Coagulation factor X (F10) Mouse IgG1 Hu E, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

Coagulation factor X (F10) antibody

Coagulation factor X (F10) Rat IgG Ms E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Coagulation factor X (F10) antibody

Coagulation factor X (F10) Rat IgG Ms E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Coagulation factor X (F10) antibody

Coagulation factor X (F10) Sheep Hu E, WB
1 mg / €390.00
  Abnova Taiwan Corp.

Coagulation factor X (F10) antibody

Coagulation factor X (F10) Sheep Ms E, WB
1 mg / €390.00
  Abnova Taiwan Corp.

Coagulation factor X (F10) antibody

Coagulation factor X (F10) Rabbit Hu E, R, WB
0.15 mg / €390.00
  Abnova Taiwan Corp.

Coagulation factor X (F10) (cleaved) antibody

Western blot analysis of extracts from rat liver cells, using FA10 (activated heavy chain,Cleaved-Ile235) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €205.00
  Assay Biotech

Coagulation factor X (F10) (cleaved) antibody

Western blot analysis of extracts from rat liver cells, using FA10 (activated heavy chain,Cleaved-Ile235) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €310.00
  Assay Biotech

Coagulation factor X (F10) (cleaved) antibody

Western blot analysis of extracts from A549 cells, treated with etoposide 24uM 24h, using FA10 (light chain,Cleaved-Ala41) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €205.00
  Assay Biotech

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