COL4A3BP antibody

Principal name

COL4A3BP antibody

Alternative names for COL4A3BP antibody

CERT, STARD11, Collagen type IV alpha-3-binding protein, Ceramide transfer protein, hCERT, Goodpasture antigen-binding protein, GPBP, StAR-related lipid transfer protein 11, START domain-containing protein 11, StARD11

SwissProt ID

Q9EQG9 (Mouse), Q9GKI7 (Bovin), Q9Y5P4 (Human)

Gene ID

10087 (COL4A3BP), 68018 (Col4a3bp)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Chk (Chicken), Rt (Rat), African clawed frog, Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P)

Background of COL4A3BP antibody

CERT mediates the ATP-dependent ER-to-Golgi transfer of ceramide in a non-vesicular manner. The biosynthesis of lipids involves steps that occur in different intracellular compartments. The movement of lipids within these compartments is important in lipid-mediated signalling. Human CERT is identical to a splice variant of human Goodpasture antigen-binding protein (GPBP26).
CERT contains a phosphoinositide-binding pleckstrin-homology (PH) domain (which targets CERT to the Golgi by binding phosphatidylinositol-4-phosphate (PtdIns4P)), a middle region, and a putative lipid-transfer-catalysing domain called START. CERT and CERTL can specifically extract ceramide from phospholipid bilayers in a START-domain-dependent manner. CERT interacts with ER membranes and specifically extracts ceramide. CERT catalyses both the specific extraction of ceramide from donor vesicles and its transfer to acceptor vesicles. CERT can associate with the Golgi in a PtdIns4P dependent manner.

General readings

Swanton C, Marani M, Pardo O, Warne PH, Kelly G, Sahai E, Elustondo F, Chang J, Temple J, Ahmed AA, Brenton JD, Downward J, Nicke B.
Regulators of mitotic arrest and ceramide metabolism are determinants of sensitivity to paclitaxel and other chemotherapeutic drugs.
Cancer. 2007 Jun;11(6):498-512.
PMID: 17560332

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

COL4A3BP antibody

  Goat Polyclonal Antibody against COL4A3BP  
TA303299 (0.5µg/ml) staining of mouse heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

COL4A3BP (396-411) antibody

  Goat Anti-COL4A3BP (aa396-411) Antibody  
TA305690 (1ug/ml) staining of Human Heart lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

COL4A3BP antibody

  Rabbit Polyclonal Anti-COL4A3BP Antibody  
WB Suggested Anti-COL4A3BP Antibody Titration: 0.2-1 ug/ml; Positive Control: Hela cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

COL4A3BP Control Peptide

COL4A3BP IgG Purified
50 µg / €220.00
  Acris Antibodies GmbH

COL4A3BP antibody

COL4A3BP Rabbit IgG Aff - Purified Hu WB
0.1 mg / €490.00
  Acris Antibodies GmbH

COL4A3BP antibody

COL4A3BP Rabbit IgG Purified Hu WB
0.1 mg / €380.00
  Acris Antibodies GmbH

COL4A3BP (N-term) antibody

COL4A3BP Antibody (N-term) (Cat. #AP51016PU-N) western blot analysis in MDA-MB453 cell line lysates (35µg/lane).This demonstrates the COL4A3BP antibody detected the COL4A3BP protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

Col4a3bp - mouse gene knockout kit via CRISPR

Col4a3bp - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Col4a3bp - mouse gene knockout kit via CRISPR

Col4a3bp - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Col4a3bp - mouse gene knockout kit via CRISPR

Col4a3bp - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Col4a3bp - mouse gene knockout kit via CRISPR

Col4a3bp - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

COL4A3BP (transcript variant 2)

  Recombinant protein of human collagen, type IV, alpha 3 (Goodpasture antigen) binding protein (COL4A3BP), transcript variant 2  
COL4A3BP Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

COL4A3BP (347-598, His-tag)

COL4A3BP Human Purified > 95 % by SDS - PAGE E. coli
0.5 mg / €670.00
  Acris Antibodies GmbH

COL4A3BP (347-598, His-tag)

COL4A3BP Human Purified > 95 % by SDS - PAGE E. coli
0.1 mg / €250.00
  Acris Antibodies GmbH

Mouse Lenti ORF Particles

Catalog No.    

Lenti ORF particles, Col4a3bp (GFP-tagged) - Mouse collagen, type IV, alpha 3 (Goodpasture antigen) binding protein (Col4a3bp), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Col4a3bp (GFP-tagged) - Mouse collagen, type IV, alpha 3 (Goodpasture antigen) binding protein (Col4a3bp), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,280.00
  OriGene Technologies, Inc.

Lenti ORF particles, Col4a3bp (GFP-tagged) - Mouse collagen, type IV, alpha 3 (Goodpasture antigen) binding protein (Col4a3bp), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Col4a3bp (GFP-tagged) - Mouse collagen, type IV, alpha 3 (Goodpasture antigen) binding protein (Col4a3bp), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,250.00
  OriGene Technologies, Inc.

Lenti ORF particles, Col4a3bp (GFP-tagged) - Mouse procollagen, type IV, alpha 3 (Goodpasture antigen) binding protein (cDNA clone MGC:27595 IMAGE:4502118),, 200 uL, >10^7 TU/mL

Lenti ORF particles, Col4a3bp (GFP-tagged) - Mouse procollagen, type IV, alpha 3 (Goodpasture antigen) binding protein (cDNA clone MGC:27595 IMAGE:4502118),, 200 uL, >10^7 TU/mL  
200 µl / €1,170.00
  OriGene Technologies, Inc.

Lenti ORF particles, Col4a3bp (Myc-DDK-tagged) - Mouse collagen, type IV, alpha 3 (Goodpasture antigen) binding protein (Col4a3bp), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, Col4a3bp (Myc-DDK-tagged) - Mouse collagen, type IV, alpha 3 (Goodpasture antigen) binding protein (Col4a3bp), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,150.00
  OriGene Technologies, Inc.

Lenti ORF particles, Col4a3bp (Myc-DDK-tagged) - Mouse collagen, type IV, alpha 3 (Goodpasture antigen) binding protein (Col4a3bp), transcript variant 2, 200 uL, >10^7 TU/mL

Lenti ORF particles, Col4a3bp (Myc-DDK-tagged) - Mouse collagen, type IV, alpha 3 (Goodpasture antigen) binding protein (Col4a3bp), transcript variant 2, 200 uL, >10^7 TU/mL  
200 µl / €1,120.00
  OriGene Technologies, Inc.

Lenti ORF particles, Col4a3bp (Myc-DDK-tagged) - Mouse procollagen, type IV, alpha 3 (Goodpasture antigen) binding protein (cDNA clone MGC:27595 IMAGE:4502118),, 200 uL, >10^7 TU/mL

Lenti ORF particles, Col4a3bp (Myc-DDK-tagged) - Mouse procollagen, type IV, alpha 3 (Goodpasture antigen) binding protein (cDNA clone MGC:27595 IMAGE:4502118),, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

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