Collagen type I alpha 2 chain antibody

Principal name

Collagen type I alpha 2 chain antibody

Alternative names for Collagen type I alpha 2 chain antibody

COL1A2, Alpha-2 type I collagen

SwissProt ID

P02465 (Bovin), P02466 (Rat), P02467 (Chick), P08123 (Human)

Gene ID

84352 (Col1a2), 1277 (COL1A1), 1278 (COL1A2), 282188

Available reactivities

Rt (Rat), Hu (Human), Ms (Mouse), Chk (Chicken), Bov (Bovine), Can (Canine), Rb (Rabbit), African clawed frog, Por (Porcine), Sh (Sheep), GP (Guinea Pig)

Available hosts

Rabbit, Mouse, Goat

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Radioimmunoassay (R), Paraffin Sections (P), Western blot / Immunoblot (WB), Frozen Sections (C), Dot blot (Dot), Immunoprecipitation (IP)

Background of Collagen type I alpha 2 chain antibody

COL1A2 is the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity.This gene encodes the pro-alpha2 chain of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIB, recessive Ehlers-Danlos syndrome Classical type, idiopathic osteoporosis, and atypical Marfan syndrome. Symptoms associated with mutations in this gene, however, tend to be less severe than mutations in the gene for the alpha1 chain of type I collagen (COL1A1) reflecting the different role of alpha2 chains in matrix integrity. Three transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Huang,H., (er) Community Dent Oral Epidemiol (2008) In press

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Collagen type I alpha 2 chain antibody

COL1A2 antibody [C2C3], C-term detects COL1A2 protein by western blot analysis. A. 30 ug 293T whole cell extract. B. 30 ug whole cell extract of GFP-human COL1A2-transfected 293T cells (partial). 10 % SDS-PAGE. COL1A2 antibody [C2C3], C-term (TA308423) di Rabbit IgG Aff - Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Collagen type I alpha 2 chain antibody

Western blot analysis of extracts from Jurkat cells, treated with etoposide (25uM, 24hours), using Collagen I a2 (Cleaved-Gly1102) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Collagen type I alpha 2 chain antibody

Western blot analysis of extracts from 293 cells and HeLa cells, using Collagen I a2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Collagen type I alpha 2 chain antibody

Predicted cell location: Cytoplasm. Positive control: Human gastric and liver cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human gastric cancer tissue using COL1A2 antibody at dilution 1/20, on the right is treated with the fusion protein. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Collagen type I alpha 2 chain antibody

Collagen type I alpha 2 chain Rabbit IgG Purified Hu, Ms, Rt P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Collagen type I alpha 2 chain antibody

WB Suggested Anti-COL1A2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Human Liver Rabbit IgG Purified GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Collagen type I alpha 2 chain antibody

Immunohistochemistry analysis of Collagen I Antibody (Cat.-No AP06516PU-N)  in paraffin-embedded human breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P
0.1 mg / €350.00
  Acris Antibodies GmbH

Collagen type I alpha 2 chain antibody

Immunohistochemistry (IHC) analyzes of COL1A2 antibody (Cat.-No.: AP20544PU-N) in paraffin-embedded human colon carcinoma tissue. Rabbit Aff - Purified Hu ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Collagen type I alpha 2 chain antibody

Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit IgG Aff - Purified Hu E, ICC/IF, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Collagen type I alpha 2 chain (N-term) antibody

COL1A2 Antibody (N-term) (Cat. #AP51013PU-N) western blot analysis in T47D cell line lysates (35µg/lane).This demonstrates the COL1A2 antibody detected the COL1A2 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Collagen type I alpha 2 chain antibody

Collagen type I alpha 2 chain Mouse IgG2a 7E11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Collagen type I alpha 2 chain antibody

Collagen type I alpha 2 chain Mouse IgG2b 2A3 Hu C
0.1 mg / €390.00
  Abnova Taiwan Corp.

Collagen type I alpha 2 chain antibody

Collagen type I alpha 2 chain Rabbit IgG Chk E, ICC/IF, P, R
0.1 ml / €470.00
  Abnova Taiwan Corp.

Collagen type I alpha 2 chain antibody

Collagen type I alpha 2 chain Goat Hu C, Dot, E, ICC/IF, WB
0.2 mg / €470.00
  Abnova Taiwan Corp.

Collagen type I alpha 2 chain antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Collagen I Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P
50 µg / €205.00
  Assay Biotech

Collagen type I alpha 2 chain antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Collagen I Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P
0.1 mg / €310.00
  Assay Biotech

Collagen type I alpha 2 chain antibody

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using Collagen I alpha2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, P, WB
50 µg / €205.00
  Assay Biotech

Collagen type I alpha 2 chain antibody

Immunohistochemistry analysis of paraffin-embedded human colon carcinoma tissue, using Collagen I alpha2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, P, WB
0.1 mg / €310.00
  Assay Biotech

Collagen type I alpha 2 chain (cleaved) antibody

Western blot analysis of extracts from Jurkat cells, treated with etoposide 25uM 24h, using Collagen I alpha2 (Cleaved-Gly1102) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €205.00
  Assay Biotech

Collagen type I alpha 2 chain (cleaved) antibody

Western blot analysis of extracts from Jurkat cells, treated with etoposide 25uM 24h, using Collagen I alpha2 (Cleaved-Gly1102) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €310.00
  Assay Biotech

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