Collagen type I antibody

Principal name

Collagen type I antibody

Alternative names for Collagen type I antibody

COL1A1, COL1A2, Alpha-1 type I collagen, Alpha-2 type I collagen

SwissProt ID

P02452 (Human), P02453 (Bovin), P02454 (Rat), P02456 (Rabit), P02457 (Chick), P11087 (Mouse), Q58P24, Q9XSJ7 (Canfa)

Gene ID

1277 (COL1A1), 12842 (Col1a1), 282187, 29393, 403651, 3371580

Available reactivities

Hu (Human), Bov (Bovine), Deer, Por (Porcine), Rb (Rabbit), Rt (Rat), Ms (Mouse), Chk (Chicken), Mam (Mammalia), Amph (Amphibian), Fi (Fish), Sh (Sheep), Goldfish, Bonito, Salmon, Sole, Tuna, Can (Canine), Gt (Goat), Ze (Zebrafish), Eq (Equine), GP (Guinea Pig)

Available hosts

Mouse, Goat, Rabbit

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Dot blot (Dot), Western blot / Immunoblot (WB), Radioimmunoassay (R), Immunoprecipitation (IP), Flow Cytometry (F)

Background of Collagen type I antibody

Collagen I is a fibrillar collagen found in most connective tissues, and the only component of the collagen found in cartilage. Mutations in this gene are associated with osteogenesis imperfecta, Ehlers Danlos syndrome, and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. Type II collagen is a fibrillar collagen found in cartilage and the vitreous humor of the eye. Collagen type II is essential for the normal embryonic development of the skeleton, for linear growth and for the ability of cartilage to resist compressive forces. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. Collagen III is a fibrillar collagen that is found in extensible connective tissues such as skin, lung, and the vascular system, frequently in association with Collagen I. Mutations in this gene are associated with Ehlers Danlos syndrome type IV, and with aortic and arterial aneurysms. Although alternate transcripts have been detected for this gene, they are the result of mutations; these mutations alter splicing, often leading to the exclusion of multiple exons.

General readings

British Journal of Haematology, (1995) 90:757-766.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Collagen type I antibody

Immunohistochemistry using affinity purified Collagen type I antibody Cat.-No R1038 at a 1/100 dilution to detect distal tubules in normal kidney tissue. Note the absence of staining of glomeruli. The antibody was reacted with antibody for 4 h RT followed by secondary antibody and substrate reaction. Tissue was Formalin-fixed and Paraffin embedded. No antigen retrieval was performed. Rabbit Purified Bov, Hu, Mam, Ms, Rt C, E, IP, P, WB
0.1 mg / €290.00
  Acris Antibodies GmbH

Collagen type I antibody

Collagen type I Rabbit Azide Free Fi C, E, ICC/IF
0.5 ml / €970.00
  Acris Antibodies GmbH

Collagen type I antibody

Collagen type I Rabbit Purified Chk C, E, ICC/IF, P, R
0.5 ml / €620.00
  Acris Antibodies GmbH

Collagen type I antibody

Collagen type I Rabbit Purified Chk C, E, ICC/IF, P, R
0.1 ml / €370.00
  Acris Antibodies GmbH

Collagen type I antibody

Flow Cytometry of Anti-Collagen Type I Biotin Conjugated Antibody Cat.-No R1038B. Cells: Mouse lung. Stimulation: none. Primary antibody: Biotin conjugated anti-Collagen type I antibody. Secondary Antibody: PE-conjugated CD45 and PE-conjugated anti-Collagen type I secondary antibody. Rabbit Biotin Bov, Hu, Mam, Ms, Rt E, F, IP, P, WB
0.1 mg / €440.00
  Acris Antibodies GmbH

Collagen type I antibody

Immunohistochemistry using affinity purified Collagen type I antibody Cat.-No R1038 at a 1/100 dilution to detect distal tubules in normal kidney tissue. Note the absence of staining of glomeruli. The antibody was reacted with antibody for 4 h RT followed by secondary antibody and substrate reaction. Tissue was Formalin-fixed and Paraffin embedded. No antigen retrieval was performed. Rabbit Purified Bov, Hu, Mam, Ms, Rt C, E, IP, P, WB
0.5 mg / €780.00
  Acris Antibodies GmbH

Collagen type I (1021-1108) antibody

Formalin-Fixed, Paraffin-Embedded Human Prostate stained with COL1A1 Antibody Cat.-No AM31694PU-N at 5 µg/ml after heat-induced antigen retrieval Mouse IgG3 3G3 Purified Hu, Ms E, P, WB
50 µg / €530.00
  Acris Antibodies GmbH

Collagen type I (Propeptide) antibody

Western blot of rat lung lysate showing specific immunolabeling of the ~180 k collagen 1 Rabbit IgG Azide Free Amph, Av, Fi, Hu, Mam, Ms C, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Collagen type I (Telopeptide) antibody

Western blot of rat lung lysate showing specific immunolabeling of  the ~ 140k collagen protein. Rabbit IgG Azide Free Amph, Av, Fi, Hu, Mam, Ms, Sh P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Collagen type I antibody

Immunohistochemistry: Collagen I Antibody [TA336830] - Analysis of Collagen 1 in mouse epidermis using DAB with hematoxylin counterstain. Rabbit Purified Hu, Ms C, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Collagen type I antibody

Immunohistochemistry: Collagen I Antibody [TA336831] - IHC analysis of Collagen 1 in mouse epidermis using DAB with hematoxylin counterstain. Rabbit Purified Hu, Ms C, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Collagen type I antibody

WB Suggested Anti-COL1A1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Human brain Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Collagen type I antibody

WB Suggested Anti-COL1A1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Human Muscle Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

Collagen type I (+ type II and III) antibody

Collagen type I Mouse IgM NLI/22 Purified Hu E, ICC/IF
1 ml / €360.00
  Acris Antibodies GmbH

Collagen type I (+ type II and III) antibody

Collagen type I Mouse IgM MCI-HA Purified Hu C, E
1 ml / €370.00
  Acris Antibodies GmbH

Collagen type I antibody

Collagen type I Goat IgG Purified Chk E, ICC/IF
0.5 ml / €510.00
  Acris Antibodies GmbH

Collagen type I antibody

Collagen type I Rabbit IgG Purified Ms C, E, ICC/IF, P, R
0.1 ml / €480.00
  Acris Antibodies GmbH

Collagen type I (+ type III) antibody

Collagen type I Rabbit IgG Purified Hu, Por C, E, ICC/IF
0.5 ml / €430.00
  Acris Antibodies GmbH

Collagen type I antibody

Prostate: Formalin-Fixed Paraffin-Embedded (FFPE) using Collagen I antibody. Rabbit IgG Biotin Bov, Hu, Mam, Ms, Rt E, IP, P, WB
0.1 mg / €530.00
  Acris Antibodies GmbH

Collagen type I antibody

Skin: Formalin-Fixed Paraffin-Embedded (FFPE) using Collagen I antibody. Rabbit Aff - Purified Bov, Hu, Mam, Ms, Rt E, IP, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

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