Collagen type IV alpha 3 chain antibody

Principal name

Collagen type IV alpha 3 chain antibody

Alternative names for Collagen type IV alpha 3 chain antibody

COL4A3

SwissProt ID

Q01955 (Human), Q28084 (Bovin), Q9QZS0 (Mouse)

Gene ID

1285 (COL4A3)

Available reactivities

Por (Porcine), Hu (Human), Rt (Rat), Ze (Zebrafish), Ms (Mouse), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit, Mouse, Goat

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Radioimmunoassay (R), Western blot / Immunoblot (WB), Frozen Sections (C)

Background of Collagen type IV alpha 3 chain antibody

Type IV collagen, the major structural component of basement membranes, is a multimeric protein composed of 3 alpha subunits. These subunits are encoded by 6 different genes, alpha 1 through alpha 6, each of which can form a triple helix structure with 2 other subunits to form type IV collagen. This gene encodes alpha 3. In the Goodpasture syndrome, autoantibodies bind to the collagen molecules in the basement membranes of alveoli and glomeruli. The epitopes that elicit these autoantibodies are localized largely to the non-collagenous C-termil domain of the protein. A specific kise phosphorylates amino acids in this same C-termil region and the expression of this kise is upregulated during pathogenesis. There are multiple alterte transcripts that appear to be unique to this human alpha 3 gene and alterte splicing is restricted to the six exons that encode this C-termil domain. This gene is also linked to an autosomal recessive form of Alport syndrome. The mutations contributing to this syndrome are also located within the exons that encode this C-termil region. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Some exons of this gene are interspersed with exons of an uncharacterized gene which is on the opposite strand.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Collagen type IV alpha 3 chain antibody

Western blot analysis of extracts from293 cells, treated with etoposide (25uM, 1hour), using Collagen IV a3 (Cleaved-Leu1425) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Collagen type IV alpha 3 chain antibody

Western blot analysis of extracts from Jurkat cells treated with etoposide (25uM, 24hours) and COS-7 cells treated with etoposide (25uM, 1hour), using Collagen IV a3 (Cleaved-Pro1426) antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Collagen type IV alpha 3 chain antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue using Collagen IV a3 antibody.The picture on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, ICC/IF, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Collagen type IV alpha 3 chain antibody

Predicted cell location: Secreted,Extracellular matrix,Extracellular space . Positive control: Human ovarian and thyroid cancer tissue . Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human ovarian cancer tissue using COL4A3 antibody at dilution 1/20, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Collagen type IV alpha 3 chain antibody

Predicted cell location: Secreted,Extracellular matrix,Extracellular space . Positive control: Human ovarian and thyroid cancer tissue . Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human ovarian cancer tissue using COL4A3 antibody at dilution 1/20, on the right is treated with the synthetic peptide. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Collagen type IV alpha 3 chain (341-353) antibody

TA329682 (4ug/ml) staining of paraffin embedded Human Kidney. Steamed antigen retrieval with citrate buffer pH 6, HRP-staining. Goat Aff - Purified Bov, Can, Hu E, P
0.1 mg / €325.00
  OriGene Technologies, Inc.

Collagen type IV alpha 3 chain antibody

WB Suggested Anti-COL4A3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Collagen type IV alpha 3 chain antibody

WB Suggested Anti-COL4A3 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: Human Liver Rabbit IgG Purified Eq, GP, Hu, Ms, Por, Rb WB
50 µg / €325.00
  OriGene Technologies, Inc.

Collagen type IV alpha 3 chain antibody

Immunofluorescence staining of Collagen IV alpha 3 chain (COL4A3) in develloping Zebrafish: At 72 hour post fertilization (hpf) antibodies to collagen IV alpha3 chain stain neuromasts and epidermis in Zebrafish. Courtesy from E. Guillon and F. Ruggiero, IGFL, ENS de Lyon, France. Rabbit Serum Hu, Rt, Ze C, E, ICC/IF, WB
0.2 ml / €400.00
  Acris Antibodies GmbH

Collagen type IV alpha 3 chain antibody

Collagen type IV alpha 3 chain Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

Collagen type IV alpha 3 chain antibody

Collagen type IV alpha 3 chain Rabbit IgG Por E, ICC/IF, P, R
0.1 ml / €560.00
  Abnova Taiwan Corp.

Collagen type IV alpha 3 chain antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Collagen IV alpha3 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, P
50 µg / €205.00
  Assay Biotech

Collagen type IV alpha 3 chain antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Collagen IV alpha3 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, ICC/IF, P
0.1 mg / €310.00
  Assay Biotech

Collagen type IV alpha 3 chain (cleaved) antibody

Western blot analysis of extracts from 293 cells, treated with etoposide 25uM 1h, using Collagen IV alpha3 (Cleaved-Leu1425) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €205.00
  Assay Biotech

Collagen type IV alpha 3 chain (cleaved) antibody

Western blot analysis of extracts from 293 cells, treated with etoposide 25uM 1h, using Collagen IV alpha3 (Cleaved-Leu1425) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €310.00
  Assay Biotech

Collagen type IV alpha 3 chain (cleaved) antibody

Western blot analysis of extracts from Jurkat/COS7 cells, treated with etoposide 25uM 24h, using Collagen IV alpha3 (Cleaved-Pro1426) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €205.00
  Assay Biotech

Collagen type IV alpha 3 chain (cleaved) antibody

Western blot analysis of extracts from Jurkat/COS7 cells, treated with etoposide 25uM 24h, using Collagen IV alpha3 (Cleaved-Pro1426) Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €310.00
  Assay Biotech

Collagen type IV alpha 3 chain antibody

Western blot analysis of Tumstatin expression in HepG2 colchicine-treated (A); HeLa UV-treated (B); Raw264.7 colchicine-treated (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

Collagen type IV alpha 3 chain antibody

Western blot analysis of Tumstatin expression in HepG2 colchicine-treated (A); HeLa UV-treated (B); Raw264.7 colchicine-treated (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

Collagen type IV alpha 3 chain antibody

Western blot analysis of Tumstatin expression in HepG2 colchicine-treated (A); HeLa UV-treated (B); Raw264.7 colchicine-treated (C) whole cell lysates. Rabbit Aff - Purified Hu, Ms WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

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