Collagen type VII antibody

Principal name

Collagen type VII antibody

Alternative names for Collagen type VII antibody

COL7A1, Long-chain collagen, LC collagen

SwissProt ID

Q02388 (Human), Q63870 (Mouse)

Gene ID

12836 (Col7a1), 1294 (COL7A1)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), GP (Guinea Pig), Gt (Goat), Por (Porcine), Sh (Sheep), Eq (Equine), Rt (Rat), Can (Canine), Marmoset, Mky (Monkey)

Available hosts

Rabbit, Mouse, Goat

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of Collagen type VII antibody

This gene encodes the alpha chain of type VII collagen. The type VII collagen fibril, composed of three identical alpha collagen chains, is restricted to the basement zone beneath stratified squamous epithelia. It functions as an anchoring fibril between the external epithelia and the underlying stroma. Mutations in this gene are associated with all forms of dystrophic epidermolysis bullosa. In the absence of mutations, however, an acquired form of this disease can result from an autoimmune response made to type VII collagen. [provided by RefSeq]

General readings

General / background references:Wetzels RH et al. Distribution patterns of type VII collagen in normal and malignant human tissues. Am J Pathol 139:451-9 (1991). PubMed PMID: 1867328
Fine JD et al. Intraepidermal type VII collagen. Evidence for abnormal intracytoplasmic processing of a major basement membrane protein in rare patients with dominant and possibly localized recessive forms of dystrophic epidermolysis bullosa. J Am Acad Dermatol 22:188-95 (1990). PubMed PMID: 2104504
Shimizu H et al. Epidermolysis bullosa acquisita antigen and the carboxy terminus of type VII collagen have a common immunolocalization to anchoring fibrils and lamina densa of basement membrane. Br J Dermatol 122:577-85 (1990). PubMed PMID: 2354110
Sanes JR et al. Molecular heterogeneity of basal laminae: isoforms of laminin and collagen IV at the neuromuscular junction and elsewhere. J Cell Biol 111:1685-99 (1990). PubMed PMID: 2211832
Kirkham N et al. Type VII collagen antibody LH 7.2 identifies basement membrane characteristics of thin malignant melanomas. J Pathol 157:243-7 (1989). PubMed PMID: 2647941
Wetzels RH et al. Detection of basement membrane components and basal cell keratin 14 in noninvasive and invasive carcinomas of the breast. Am J Pathol 134:571-9 (1989). PubMed PMID: 2466404
Leigh IM et al. Epithelia 1:17 (1987).Heagerty AH et al. Identification of an epidermal basement membrane defect in recessive forms of dystrophic epidermolysis bullosa by LH 7:2 monoclonal antibody: use in diagnosis. Br J Dermatol 115:125-31 (1986). PubMed PMID: 3527251

14 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Collagen type VII antibody

TA303034 (0.5µg/ml) staining of rat testis lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Can, Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Collagen type VII antibody

Figure 2. Immunofluorescence of Collagen VII staining in Cryosections of Murine (A) and Human Skin (B). This antibody AP02276PU stains the Dermal-Epidermal Junction (DEJ). Original magnification 250x. 
Sitaru C et al. (2005). J. Clin. Invest. 115 (4):870-8. Rabbit Ig Fraction Hu, Ms C, E, ICC/IF, WB
0.1 mg / €540.00
  Acris Antibodies GmbH

Collagen type VII antibody

Figure 2. Immunofluorescence of Collagen VII staining in Cryosections of Murine (A) and Human Skin (B). This antibody AP02276PU stains the Dermal-Epidermal Junction (DEJ). Original magnification 250x. 
Sitaru C et al. (2005). J. Clin. Invest. 115 (4):870-8. Rabbit Ig Fraction Hu, Ms C, E, ICC/IF, WB
10 µg / €190.00
  Acris Antibodies GmbH

Collagen type VII antibody

Immunofluorescence: AP23436PU Collagen VII antibody staining of Murine Skin Cryosection. The sections was incubated with AP23436PU followed by an appropriate secondary antibody coupled to FITC Mouse IgG Purified Ms C, ICC/IF
0.1 mg / €1,330.00
  Acris Antibodies GmbH

Collagen type VII antibody

Immunofluorescence: AP23436PU Collagen VII antibody staining of Murine Skin Cryosection. The sections was incubated with AP23436PU followed by an appropriate secondary antibody coupled to FITC Mouse IgG Purified Ms C, ICC/IF
10 µg / €250.00
  Acris Antibodies GmbH

Collagen type VII (NC1 CMP / VWFA1 Dom.) antibody

Collagen type VII Rabbit Purified Ms C, E, ICC/IF, WB
0.1 mg / €540.00
  Acris Antibodies GmbH

Collagen type VII (NC1 FN-III-like Dom 7+8) antibody

Immunofluorescence of Collagen VII staining of Cryosections of Murine Skin. The section was incubated with AP23438PU followed by an appropriate secondary antibody coupled to Fluorescein. This antibody marks the dermal-epidermal junction (DEJ).
See Sesarman et al. (2008) J. Mol. Med 86(8): 951-959. Rabbit Purified Ms C, E, ICC/IF
0.1 mg / €540.00
  Acris Antibodies GmbH

Collagen type VII (NC1 FN-III-like Dom 7+8) antibody

Immunofluorescence of Collagen VII staining of Cryosections of Murine Skin. The section was incubated with AP23438PU followed by an appropriate secondary antibody coupled to Fluorescein. This antibody marks the dermal-epidermal junction (DEJ).
See Sesarman et al. (2008) J. Mol. Med 86(8): 951-959. Rabbit Purified Ms C, E, ICC/IF
10 µg / €190.00
  Acris Antibodies GmbH

Collagen type VII antibody

Collagen type VII Mouse IgG1 LH7.2 Bov, GP, Gt, Hu, Marmoset, Mky, Sh C
1 ml / €640.00
  Abnova Taiwan Corp.

Collagen type VII antibody

COL7A1 polyclonal antibody ( Cat # PAB7538 ) ( 0.5 µg/ml ) staining of rat testis lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Rt E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

Collagen type VII antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Collagen VII alpha1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, P
50 µg / €205.00
  Assay Biotech

Collagen type VII antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Collagen VII alpha1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, P
0.1 mg / €310.00
  Assay Biotech

Collagen type VII antibody

Collagen type VII Mouse IgG1 LH7.2 Ascites Bov, Eq, GP, Gt, Por, Sh C, E, ICC/IF, P, WB
0.1 ml / €360.00
  Novus Biologicals Inc.

Collagen type VII antibody

NBP1-00174 (0.5ug/ml) staining of rat testis lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat IgG Aff - Purified Hu, Rt E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

14 Item(s)

per page
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