Complement C4B antibody
Principal name
Complement C4B antibody
Alternative names for Complement C4B antibody
Complement component 4, Basic complement C4, CO4, CPAMD3, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3
Ncbi ID
Available reactivities
Available hosts
Available applications
Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Flow Cytometry (F)
Background of Complement C4B antibody
C4B is the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.




Primary Antibodies
Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
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AM26326PU-N | Complement C4 (C4b+C4d) antibody |
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Rat | IgG2a | 16D2 | Purified | Ms | C, E, ICC/IF, IP, WB |
0.1 mg /
€440.00
|
Acris Antibodies GmbH | |||||||
TA316579 | Complement C4b antibody |
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Complement C4B Chicken Polyclonal Antibody | |||||||
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Chicken | Ig | Purified | Hu | E, F, P, WB |
50 µg /
€400.00
|
|
OriGene Technologies, Inc. | |||||||
TA346240 | Complement C4B antibody |
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Rabbit Polyclonal Anti-C4B Antibody | |||||||
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Rabbit | IgG | Purified | Can, Eq, GP, Hu, Ms, Por, Rt | WB |
50 µg /
€360.00
|
|
OriGene Technologies, Inc. | |||||||
AP22740PU-N | Complement C4B (C4d) antibody |
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Rabbit | Aff - Purified | Hu | P |
0.25 ml /
€380.00
|
||
Acris Antibodies GmbH | |||||||
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CRISPR
Catalog No. | Species | Donor Vector | |
---|---|---|---|
KN235334 | C4B_2 - human gene knockout kit via CRISPR |
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Human | GFP-Puro |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN209211 | C4B - human gene knockout kit via CRISPR |
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Human | GFP-Puro |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN209211BN | C4B - human gene knockout kit via CRISPR |
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Human | mBFP-Neo |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN209211LP | C4B - human gene knockout kit via CRISPR |
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Human | Luciferase-Puro |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN209211RB | C4B - human gene knockout kit via CRISPR |
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Human | RFP-BSD |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN302380 | C4b - mouse gene knockout kit via CRISPR |
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Mouse | GFP-Puro |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN302380BN | C4b - mouse gene knockout kit via CRISPR |
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Mouse | mBFP-Neo |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN302380LP | C4b - mouse gene knockout kit via CRISPR |
||
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Mouse | Luciferase-Puro |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. | |||
KN302380RB | C4b - mouse gene knockout kit via CRISPR |
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Mouse | RFP-BSD |
1 kit /
€1,290.00
|
OriGene Technologies, Inc. |