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Complement C4B antibody

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Principal name

Complement C4B antibody

Alternative names for Complement C4B antibody

Complement component 4, Basic complement C4, CO4, CPAMD3, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3

SwissProt ID

P01029 (Mouse), P0C0L5 (Human)

Gene ID

100293534 (LOC100293534), 12268 (C4b), 102643089 (LOC102643089), 721 (C4B)

Ncbi ID

NP_001002029.3, NP_001002029, NP_033910.2

Available reactivities

Hu (Human), Ms (Mouse), Por (Porcine), Rt (Rat), Can (Canine), Eq (Equine), GP (Guinea Pig)

Available hosts

Mouse, Rabbit, Rat, Chicken

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Flow Cytometry (F)

Background of Complement C4B antibody

C4B is the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

ARP41841_P050 - Complement C4B
Human HeLa; WB Suggested Anti-C4B Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: Hela cell lysate; C4B antibody - N-terminal region (ARP41841_P050) in Human HeLa cells using Western Blot
AP22740PU-N - Complement C4B
Human Placenta (formalin-fixed, paraffin-embedded) stained with C4B antibody AP22740PU-N at 10 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
AP22740PU-N - Complement C4B
Human Liver (formalin-fixed, paraffin-embedded) stained with C4B antibody AP22740PU-N at 10 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen.
TA316579 - Complement C4b
Anti-C4B antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml.
TA353608 - Complement C4B
Human Tonsil stained with anti-C4d antibody.
TA353608 - Complement C4B
Human Tonsil stained with anti-C4d antibody.
TA353607 - Complement C4B
Human Tonsil stained with anti-C4d antibody.
TA346240 - Complement C4B
WB Suggested Anti-C4B Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Hela cell lysate

13 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Complement C4 (C4b+C4d) antibody
Complement C4 Rat IgG2a 16D2 Purified Ms C, E, ICC/IF, IP, WB
0.1 mg / €440.00
  Acris Antibodies GmbH

Complement C4b antibody
  Complement C4B Chicken Polyclonal Antibody  
Complement C4b Chicken Ig Purified Hu E, F, P, WB
50 µg / €400.00
  OriGene Technologies, Inc.

Complement C4B antibody
  Rabbit Polyclonal Anti-C4B Antibody  
WB Suggested Anti-C4B Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Hela cell lysate Rabbit IgG Purified Can, Eq, GP, Hu, Ms, Por, Rt WB
50 µg / €360.00
  OriGene Technologies, Inc.

Complement C4B (C4d) antibody
Human Placenta (formalin-fixed, paraffin-embedded) stained with C4B antibody AP22740PU-N at 10 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Rabbit Aff - Purified Hu P
0.25 ml / €380.00
  Acris Antibodies GmbH
+1 additional image

CRISPR

Catalog No. Species Donor Vector  

C4B_2 - human gene knockout kit via CRISPR
C4B_2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

C4B - human gene knockout kit via CRISPR
C4B - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

C4B - human gene knockout kit via CRISPR
C4B - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

C4B - human gene knockout kit via CRISPR
C4B - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

C4B - human gene knockout kit via CRISPR
C4B - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

C4b - mouse gene knockout kit via CRISPR
C4b - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

C4b - mouse gene knockout kit via CRISPR
C4b - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

C4b - mouse gene knockout kit via CRISPR
C4b - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

C4b - mouse gene knockout kit via CRISPR
C4b - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

13 Item(s)

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13 products - FILTER YOUR RESULTS!

Available Filters

Product Type
  1. CRISPR (9)
  2. Primary Antibody (4)
Clonality
  1. Polyclonal (3)
  2. Monoclonal (1)
Target
  1. Complement C4 (1)
  2. Complement C4B (2)
  3. Complement C4b (1)
Property
  1. C4b+C4d (1)
  2. C4d (1)
Reactivity
  1. Human (Hu) (3)
  2. Mouse (Ms) (2)
  3. Canine (Can) (1)
  4. Equine (Eq) (1)
  5. Guinea Pig (GP) (1)
  6. Porcine (Por) (1)
  7. Rat (Rt) (1)
Applications
  1. Western blot / Immunoblot (WB) (3)
  2. Enzyme Immunoassay (E) (2)
  3. Paraffin Sections (P) (2)
  4. Frozen sections (C) (1)
  5. Flow cytometry (F) (1)
  6. Immunocytochemistry/​Immunofluorescence (ICC/IF) (1)
  7. Immunoprecipitation (IP) (1)
Presentation
  1. Purified (3)
  2. Aff - Purified (1)
Host
  1. Rabbit (2)
  2. Chicken (1)
  3. Rat (1)
Images
  1. 1 image (2)
Images: Applications
  1. Paraffin Sections (P) (1)
  2. Western blot / Immunoblot (WB) (1)
Species (CRISPR)
  1. Human (5)
  2. Mouse (4)
Donor Vector
  1. GFP-Puro (3)
  2. Luciferase-Puro (2)
  3. RFP-BSD (2)
  4. mBFP-Neo (2)
Manufacturer
  1. Acris - OriGene (13)
Service
  • OriGene EU
  • Acris Antibodies GmbH
  • Schillerstraße 5
  • D-32052 Herford
  • Germany
  • phone: +49-5221-34606-0
  • free call: 0800-227 47 46 (Germany only)
  • fax: +49-5221-34606-11
  • email: info@acris-online.de
  • orders: ordering@acris-online.de
 
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