Complement C4B antibody

Principal name

Complement C4B antibody

Alternative names for Complement C4B antibody

Complement component 4, Basic complement C4, CO4, CPAMD3, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3

SwissProt ID

P01029 (Mouse), P0C0L5 (Human)

Gene ID

100293534 (LOC100293534), 12268 (C4b), 102643089 (LOC102643089), 721 (C4B)

Available reactivities

Hu (Human), Ms (Mouse), Por (Porcine), Rt (Rat), Can (Canine), Eq (Equine), GP (Guinea Pig)

Available hosts

Mouse, Rabbit, Rat, Chicken

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C), Flow Cytometry (F)

Background of Complement C4B antibody

C4B is the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

15 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Complement C4 (C4b+C4d) antibody

Complement C4 Rat IgG2a 16D2 Purified Ms C, E, ICC/IF, IP, WB
0.1 mg / €420.00
  Acris Antibodies GmbH

Complement C4b antibody

  Complement C4B Chicken Polyclonal Antibody  
Anti-C4B antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml. Chicken Ig Purified Hu E, F, P, WB
50 µg / €400.00
  OriGene Technologies, Inc.

Complement C4B antibody

  Rabbit Polyclonal Anti-C4B Antibody  
WB Suggested Anti-C4B Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 62500; Positive Control: Hela cell lysate Rabbit IgG Purified Can, Eq, GP, Hu, Ms, Por, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

Complement C4B antibody

  Rabbit Polyclonal anti-C4d Antibody  
Human Tonsil stained with anti-C4d antibody. Rabbit IgG Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Complement C4B antibody

  Rabbit Monoclonal anti-C4d Antibody  
Human Tonsil stained with anti-C4d antibody. Rabbit IgG SP91 Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Complement C4B (C4d) antibody

Human Placenta (formalin-fixed, paraffin-embedded) stained with C4B antibody AP22740PU-N at 10 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Rabbit Aff - Purified Hu P
0.25 ml / €470.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

C4B_2 - human gene knockout kit via CRISPR

C4B_2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

C4B - human gene knockout kit via CRISPR

C4B - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

C4B - human gene knockout kit via CRISPR

C4B - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

C4B - human gene knockout kit via CRISPR

C4B - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

C4B - human gene knockout kit via CRISPR

C4B - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

C4b - mouse gene knockout kit via CRISPR

C4b - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

C4b - mouse gene knockout kit via CRISPR

C4b - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

C4b - mouse gene knockout kit via CRISPR

C4b - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

C4b - mouse gene knockout kit via CRISPR

C4b - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

15 Item(s)

per page
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