Complement C9 antibody

Principal name

Complement C9 antibody

Alternative names for Complement C9 antibody

Complement component C9, Complement 9

SwissProt ID

P02748 (Human), P06683 (Mouse), P48747 (Rabit), P48770 (Horse), Q3MHN2 (Bovin), Q62930 (Rat)

Gene ID

735 (C9), 1466928 (Q9Z8U5)

Available reactivities

Hu (Human), Ms (Mouse), Eq (Equine), Por (Porcine), Rt (Rat)

Available hosts

Sheep, Mouse, Rabbit, Goat

Available applications

Immunodiffusion (ID), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Frozen Sections (C), Flow Cytometry (F), Functional assay (FN)

Background of Complement C9 antibody

The three distinct activation pathways of complement converge with the formation of a C5 convertase. The cleavage of C5 by this convertase initiates the lytic or terminal pathway. In contrast to the activation pathways, which require enzymatic cleavage for activation, the terminal pathway relies on conformational changes induced by binding. Binding of C6 facilitates binding of C7 which alters the conformation of the complex. After binding of C8, a variable number of C9 molecules associate with the C5b678 complex, which is also termed  the terminal complement complex (TCC). The formation of TCC causes lysis of cells or can trigger a variety of cellular metabolic pathways resulting in the synthesis and release of inflammatory mediators. The TCC contains neoantigens that are absent from the individual native components.  C9 neoantigens are present both in the membrane-bound (MAC) and the fluid-phase (SC5b-9) complex. TCC is present in normal human plasma and increased in patients with complement activation.

General readings

Lint TF, Zeitz HJ, et al. (1980) J. Immunol. 125 (5): 2252–7

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Complement C9 (184-411) antibody

Human Small Intestine, Vessels: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Aff - Purified Hu ICC/IF, P, WB
50 µl / €470.00
  Acris Antibodies GmbH

Complement C9 antibody

Western blot analysis of extracts from COLO cells, using C9 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Complement C9 (205-216) antibody

TA326742 (2µg/ml) staining of Human Placenta lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Complement C9 antibody

Complement C9 Mouse IgG2b 002-94.8.8 Purified Hu E
0.1 mg / €400.00
  Acris Antibodies GmbH

Complement C9 antibody

Complement C9 Mouse IgG2a aE11 FITC Eq, Hu, Por C, E, FN, ICC/IF, P
0.1 mg / €490.00
  Acris Antibodies GmbH

Complement C9 antibody

Complement C9 Mouse IgG2a aE11 Purified Eq, Hu, Por C, E, FN, ICC/IF, P
0.1 mg / €450.00
  Acris Antibodies GmbH

Complement C9 antibody

Complement C9 Mouse IgG1 X197 FITC Hu C, E, FN, P, WB
0.1 mg / €490.00
  Acris Antibodies GmbH

Complement C9 antibody

Complement C9 Mouse IgG1 X197 Purified Hu C, E, FN, P, WB
0.1 mg / €390.00
  Acris Antibodies GmbH

Complement C9 antibody

Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) Mouse IgG1 64E9 Liquid Hu P, WB
50 µl / €470.00
  Acris Antibodies GmbH

Complement C9 antibody

Western blot (WB) analysis of C9 antibody (Cat.-No.: AP21155PU-N) in extracts from COLO cells. Rabbit Aff - Purified Hu WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Complement C9 antibody

Immunoblot analysis of human plasma protein. Lane 1 : Complement factor C9 isolated from human plasma. Lane 2 : Human plasma. Mouse IgG1 64E9 Hu WB
0.1 ml / €390.00
  Abnova Taiwan Corp.

Complement C9 antibody

Western blot analysis of extracts from COLO cells, using C9 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €205.00
  Assay Biotech

Complement C9 antibody

Western blot analysis of extracts from COLO cells, using C9 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €310.00
  Assay Biotech

Complement C9 antibody

Immunohistochemical analysis of Complement C9 staining in human liver cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. AEC was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

Complement C9 antibody

Immunohistochemical analysis of Complement C9 staining in human liver cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. AEC was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

Complement C9 antibody

Immunohistochemical analysis of Complement C9 staining in human liver cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. AEC was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Hu P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

Complement C9 antibody

Complement C9 Mouse IgG1 Purified Hu E
0.1 mg / €360.00
  Novus Biologicals Inc.

Complement C9 antibody

Complement C9 Rabbit Aff - Purified Hu WB
0.1 mg / €420.00
  Novus Biologicals Inc.

Complement C9 antibody

Complement C9 Mouse IgG1 X197 Purified Hu C, E, F, P, WB
50 µg / €400.00
  Novus Biologicals Inc.

Complement C9 antibody

Complement C9 Rabbit IgG Aff - Purified Hu E, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

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