Complexin-1 antibody

Principal name

Complexin-1 antibody

Alternative names for Complexin-1 antibody

Complexin I, Synaphin-2, CPLX1, CPX I

SwissProt ID

O14810 (Human), P63040 (Mouse), P63041 (Rat), Q0IIL7 (Bovin)

Gene ID

10815 (CPLX1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine)

Available hosts

Rabbit, Chicken

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P), Western blot / Immunoblot (WB)

Background of Complexin-1 antibody

Complexin-1 belongs to a family of SNARE complex binding proteins that were suggested to be either facilitators or inhibitors of vesicle exocytosis. Complexin 1 exhibits reduced Ca2+-triggered fast neurotransmitter release at hippocampal glutamatergic synapses, indicating that this protein is a positive regulator of transmitter release. In contrast, it inhibits SNARE-mediated liposome and cell fusions in vitro, which lead to the hypothesis that it acts as fusion clamps of synaptic exocytosis.

General readings

General / background references:McMahon HT et al. Complexins: cytosolic proteins that regulate SNAP receptor function. Cell 83:111-9 (1995). PubMed PMID: 7553862

7 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Complexin-1 (Center) antibody

Formalin-fixed,  paraffin-embedded human brain tissue reacted with Complexin-1 Antibody (Center) Cat.-No AP51050PU-N, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Complexin-1 antibody

E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. ( anti-CPLX1 ) Chicken Aff - Purified Bov, Hu, Ms, Rt WB
50 µg / €520.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Complexin-1

Complexin-1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Complexin-1 (1-134, His-tag)

Complexin-1 Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €540.00
  Acris Antibodies GmbH

Complexin-1 (1-134, His-tag)

Complexin-1 Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €230.00
  Acris Antibodies GmbH

Complexin-1

Complexin-1 Human in vitro transl.
2 µg / €300.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

CPLX1 overexpression lysate

CPLX1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

7 Item(s)

per page
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