Concanavalin-A antibody

Principal name

Concanavalin-A antibody

Alternative names for Concanavalin-A antibody

Con-A, ConA, Concanavalin A

SwissProt ID

P02866 (Canen)

Ncbi ID

3823

Available reactivities

Jack Bean

Available hosts

Goat

Available applications

Frozen Sections (C), Immunodiffusion (ID), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Concanavalin-A antibody

Concanavalin A (ConA) is a lectin (carbohydrate-binding protein) originally extracted from the jack-bean, Canavalia ensiformis. It is a member of the legume lectin family. It binds specifically to certain structures found in various sugars, glycoproteins, and glycolipids, mainly internal and nonreducing terminal α-D-mannosyl and α-D-glucosyl groups. ConA is a plant mitogen, and is known for its ability to stimulate mouse T-cell subsets giving rise to four functionally distinct T cell populations, including precursors to suppressor T-cell; one subset of human suppressor T-cells as well is sensitive to ConA. ConA was the first lectin to be available on a commercial basis, and is widely used in biology and biochemistry to characterize glycoproteins and other sugar-containing entities on the surface of various cells. It is also used to purify glycosylated macromolecules in lectin affinity chromatography, as well as to study immune regulation by various immune cells.

General readings

Dwyer JM, Johnson C (Nov 1981). "The use of concanavalin A to study the immunoregulation of human T cells". Clin Exp Immunol 46 (2): 237–49.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Concanavalin-A antibody

Concanavalin-A Goat IgG HRP Jack Bean C, ICC/IF, ID
1 ml / €340.00
  Acris Antibodies GmbH

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