Copine-1 antibody

Principal name

Copine-1 antibody

Alternative names for Copine-1 antibody

CPNE1, CPN1, Copine I

SwissProt ID

Q8C166 (Mouse), Q99829 (Human)

Gene ID

8904 (CPNE1)

Available reactivities

Hu (Human), Bov (Bovine), Can (Canine), Chk (Chicken), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), African clawed frog, Ze (Zebrafish), Eq (Equine), GP (Guinea Pig), Sh (Sheep)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunoprecipitation (IP)

Background of Copine-1 antibody

Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. CPNE1 is a calcium-dependent protein that also contains two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. However, the protein does not contain a predicted signal sequence or transmembrane domains. This protein has a broad tissue distribution and it may function in membrane trafficking.Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene encodes a calcium-dependent protein that also contains two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. However, the encoded protein does not contain a predicted signal sequence or transmembrane domains. This protein has a broad tissue distribution and it may function in membrane trafficking. This gene and the gene for RNA binding motif protein 12 overlap at map location 20q11.21. Sequence analysis identified multiple alternatively spliced variants in the 5\' UTR. All variants encode the same protein.

General readings

1. Zhang Y, Gao Q, Duan S, He Y, Sun X, Jiang R, Duan Y, Zhong X, Ge J. Upregulation of Copine1 in trabecular meshwork cells of POAG patients: a membrane proteomics approach. Molecular vision 2008 14 : 1028-36.
PMID: 18523666

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Copine-1 antibody

Western blot analysis of CPNE1 over-expressed 293 cell line, cotransfected with CPNE1 Validated Chimera RNAi ( Cat # H00008904-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with CPNE1 monoclonal antibody (M01), clone 8B8 (Cat # H00008904-M01 ). GAPDH ( 36.1 kDa ) used as specificity and loading control. Mouse IgG2a 8B8 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Copine-1 (C-term) antibody

(0.1ug/ml) staining of Human Skin lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Copine-1 antibody

WB Suggested Anti-CPNE1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: 293T cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Sh, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Copine-1 antibody

WB Suggested Anti-CPNE1 Antibody Titration: 5.0 ug/ml; Positive Control: HepG2 cell lysateCPNE1 is supported by BioGPS gene expression data to be expressed in HepG2 Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Sh, Ze P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Copine-1 antibody

Copine-1 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Copine-1 antibody

Western Blot analysis of CPNE1 expression in transfected 293T cell line (H00008904-T01) by CPNE1 MaxPab polyclonal antibody.

Lane1:CPNE1 transfected lysate(59.07 KDa).
Lane2:Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

Copine-1 antibody

Copine-1 Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Copine-1 antibody

Copine-1 Rabbit Serum Hu E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

Copine-1 antibody

Western Blot analysis of CPNE1 expression in transfected 293T cell line (H00008904-T02) by CPNE1 MaxPab polyclonal antibody.

Lane 1: CPNE1 transfected lysate(59.10 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Copine-1 antibody

Human Hela; Host:Rabbit. Target Name:CPNE1. Sample Tissue:Human Hela. Antibody Dilution: 1.0ug/ml. CPNE1 is supported by BioGPS gene expression data to be expressed in HeLa.; CPNE1 antibody - middle region (ARP40503_P050) in Human Hela cells using Western Blot Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rb, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

Copine-1 antibody

Human Intestine; Rabbit Anti-CPNE1 Antibody. Catalog Number: ARP40504. Paraffin Embedded Tissue: Human Intestine. Cellular Data: Epithelial cells of intestinal villas. Antibody Concentration: 4.0-8.0 ug/ml. Magnification: 400X; CPNE1 antibody - N-terminal region (ARP40504_T100) in Human Intestine cells using Immunohistochemistry Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Por, Rb, Rt P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

Copine-1 antibody

(30 µg of whole cell lysate) Western Blot:  CPNE1 Antibody [NBP1-32194]- A:293T B:A431 C:H1299 7.5% SDS PAGE diluted at 1:1000 Rabbit IgG Hu P, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

Copine-1 antibody

Copine-1 Goat Aff - Purified Bov, Can, Hu E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

Copine-1 antibody

Western Blot: CPNE1 Antibody [NBP1-57418] - This Anti-CPNE1 antibody was used in Western Blot of HepG2 tissue lysate at a concentration of 5ug/ml. Rabbit Purified Hu P, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Copine-1 (transcript variant 5)

Copine-1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Copine-1 (transcript variant 1)

Copine-1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Copine-1 (transcript variant 2)

Copine-1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Copine-1 (transcript variant 4)

Copine-1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Copine-1

Copine-1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Copine-1

Copine-1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

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