Copine-1 antibody

Principal name

Copine-1 antibody

Alternative names for Copine-1 antibody

CPNE1, CPN1, Copine I

SwissProt ID

Q8C166 (Mouse), Q99829 (Human)

Gene ID

8904 (CPNE1), 266692 (Cpne1)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), Ze (Zebrafish), Chk (Chicken), African clawed frog, Eq (Equine), GP (Guinea Pig), Sh (Sheep)

Available hosts

Rabbit, Mouse, Goat

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Immunoprecipitation (IP)

Background of Copine-1 antibody

Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. CPNE1 is a calcium-dependent protein that also contains two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. However, the protein does not contain a predicted signal sequence or transmembrane domains. This protein has a broad tissue distribution and it may function in membrane trafficking.Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene encodes a calcium-dependent protein that also contains two N-terminal type II C2 domains and an integrin A domain-like sequence in the C-terminus. However, the encoded protein does not contain a predicted signal sequence or transmembrane domains. This protein has a broad tissue distribution and it may function in membrane trafficking. This gene and the gene for RNA binding motif protein 12 overlap at map location 20q11.21. Sequence analysis identified multiple alternatively spliced variants in the 5\' UTR. All variants encode the same protein.

General readings

1. Zhang Y, Gao Q, Duan S, He Y, Sun X, Jiang R, Duan Y, Zhong X, Ge J. Upregulation of Copine1 in trabecular meshwork cells of POAG patients: a membrane proteomics approach. Molecular vision 2008 14 : 1028-36.
PMID: 18523666

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Copine-1 (C-term) antibody

  Goat Anti-CPNE1 / Copine 1 Antibody  
(0.1ug/ml) staining of Human Skin lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Copine-1 antibody

  Rabbit Polyclonal Anti-CPNE1 Antibody  
WB Suggested Anti-CPNE1 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: 293T cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Sh, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

Copine-1 antibody

  Rabbit Polyclonal Anti-CPNE1 Antibody  
WB Suggested Anti-CPNE1 Antibody Titration: 5.0 ug/ml; Positive Control: HepG2 cell lysateCPNE1 is supported by BioGPS gene expression data to be expressed in HepG2 Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Sh, Ze P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CRISPR

Catalog No. Species Donor Vector  

CPNE1 - human gene knockout kit via CRISPR

CPNE1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Cpne1 - mouse gene knockout kit via CRISPR

Cpne1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Cpne1 - mouse gene knockout kit via CRISPR

Cpne1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cpne1 - mouse gene knockout kit via CRISPR

Cpne1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cpne1 - mouse gene knockout kit via CRISPR

Cpne1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Copine-1 (transcript variant 5)

  Purified recombinant protein of Homo sapiens copine I (CPNE1), transcript variant 5  
Copine-1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Copine-1 (transcript variant 1)

  Purified recombinant protein of Homo sapiens copine I (CPNE1), transcript variant 1  
Copine-1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Copine-1 (transcript variant 2)

  Purified recombinant protein of Homo sapiens copine I (CPNE1), transcript variant 2  
Copine-1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Copine-1 (transcript variant 4)

  Purified recombinant protein of Homo sapiens copine I (CPNE1), transcript variant 4  
Copine-1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Lysates

Catalog No.    

CPNE1 overexpression lysate

CPNE1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

CPNE1 overexpression lysate

CPNE1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

CPNE1 overexpression lysate

CPNE1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

CPNE1 overexpression lysate

CPNE1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, CPNE1 (mGFP-tagged)-Human copine I (CPNE1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, CPNE1 (mGFP-tagged)-Human copine I (CPNE1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

Lenti ORF particles, CPNE1 (mGFP-tagged)-Human copine I (CPNE1), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, CPNE1 (mGFP-tagged)-Human copine I (CPNE1), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €1,340.00
  OriGene Technologies, Inc.

Lenti ORF particles, CPNE1 (mGFP-tagged)-Human copine I (CPNE1), transcript variant 3, 200 uL, >10^7 TU/mL

Lenti ORF particles, CPNE1 (mGFP-tagged)-Human copine I (CPNE1), transcript variant 3, 200 uL, >10^7 TU/mL  
200 µl / €1,170.00
  OriGene Technologies, Inc.

Lenti ORF particles, CPNE1 (mGFP-tagged)-Human copine I (CPNE1), transcript variant 4, 200 uL, >10^7 TU/mL

Lenti ORF particles, CPNE1 (mGFP-tagged)-Human copine I (CPNE1), transcript variant 4, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

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