COPS2 / TRIP15 antibody

Principal name

COPS2 / TRIP15 antibody

Alternative names for COPS2 / TRIP15 antibody

TRIP-15, CSN2, SGN2, Alien homolog, COP9 signalosome complex subunit 2, JAB1-containing signalosome subunit 2, Thyroid receptor-interacting protein 15

SwissProt ID

P61201 (Human), P61202 (Mouse), P61203 (Rat)

Gene ID

9318 (COPS2), 1447 (CSN2), 261736 (Cops2)

Available reactivities

Hu (Human), Dros (Drosophila), Bov (Bovine), Can (Canine), Ms (Mouse), Por (Porcine), Rt (Rat), Ze (Zebrafish), African clawed frog, Chk (Chicken), Eq (Equine), Rb (Rabbit), GP (Guinea Pig)

Available hosts

Rabbit, Mouse, Goat

Available applications

Paraffin Sections (P), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Frozen Sections (C)

Background of COPS2 / TRIP15 antibody

Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. Involved in early stage of neuronal differentiation via its interaction with NIF3L1.

General readings

1. Escher N, Kob R, Tenbaum SP, Eisold M, Baniahmad A, von Eggeling F, Melle C.
Various members of the E2F transcription factor family interact in vivo with the corepressor alien.
J Proteome Res. 2007 Mar;6(3):1158-64. PMID: 17330949

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

COPS2 / TRIP15 (C-term) antibody

TA302410 staining (1µg/ml) of NIH-3T3 lysates (RIPA buffer, 30µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

COPS2 / TRIP15 antibody

Western blot analysis of extracts from COS-7 cells and COLO205 cells, using COPS2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

COPS2 / TRIP15 antibody

WB Suggested Anti-COPS2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:62500; Positive Control: HepG2 cell lysate Rabbit IgG Purified Can, Eq, Hu, Ms, Por, Rb, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

COPS2 / TRIP15 antibody

WB Suggested Anti-COPS2 Antibody; Titration: 0.5 ug/ml; Positive Control: Fetal Liver Rabbit IgG Purified Can, Eq, Hu, Ms, Por, Rb, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

COPS2 / TRIP15 antibody

WB Suggested Anti-COPS2 Antibody Titration: 0.5 ug/ml; ELISA Titer: 1:62500; Positive Control: Jurkat cell lysate Rabbit IgG Purified Can, Eq, Hu, Ms, Por, Rb, Ze WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

COPS2 / TRIP15 antibody

WB Suggested Antibody Titration: 2.5 ug/ml; Positive Control: 293T; COPS2 is strongly supported by BioGPS gene expression data to be expressed in Human HEK293T cells Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Ze P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

COPS2 / TRIP15 antibody

Western blot analysis of TRIP15 Antibody (Cat.-No AP01234PU-N) in extracts from COS-7 cells. Rabbit Aff - Purified Hu, Ms, Rt WB
0.1 mg / €350.00
  Acris Antibodies GmbH

COPS2 / TRIP15 (439-451) antibody

Thyroid: Formalin-Fixed, Paraffin-Embedded (FFPE) Goat Aff - Purified Bear, Bov, Bt, Can, Chk, Elephant, Eq, Fi, Hu, Mky, Ms, Op, Por, Prim, Rb, Rt, Tr, Xen E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

COPS2 / TRIP15 antibody

COPS2 / TRIP15 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

COPS2 / TRIP15 antibody

COPS2 polyclonal antibody (A01), Lot # 060501JCS1 Western Blot analysis of COPS2 expression in SJCRH30 ( Cat # L027V1 ). Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

COPS2 / TRIP15 antibody

COPS2 monoclonal antibody (M02), clone 4B12. Western Blot analysis of COPS2 expression in Raw 264.7(Cat # L024V1 ). Mouse IgG2a 4B12 Purified Hu, Ms, Rt E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

COPS2 / TRIP15 antibody

COPS2 polyclonal antibody ( Cat # PAB6396 ) staining ( 1 µg/ml ) of NIH/3T3 lysates ( RIPA buffer, 30 µg total protein per lane ) . Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Goat Hu, Ms E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

COPS2 / TRIP15 antibody

Immunofluorescence analysis of A549 cells, using COPS2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
50 µg / €205.00
  Assay Biotech

COPS2 / TRIP15 antibody

Immunofluorescence analysis of A549 cells, using COPS2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €310.00
  Assay Biotech

COPS2 / TRIP15 antibody

Human HepG2; WB Suggested Anti-COPS2 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:62500. Positive Control: HepG2 cell lysate; COPS2 antibody - N-terminal region (ARP34188_P050) in Human HepG2 cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Dros, Hu, Ms, Por, Rt, Ze WB
50 µg / €350.00
  AVIVA Systems Biology

COPS2 / TRIP15 antibody

Human Fetal liver; WB Suggested Anti-COPS2 Antibody. . Titration: 0.5 ug/ml. . Positive Control: Fetal Liver; COPS2 antibody - N-terminal region (ARP34189_P050) in Human Fetal liver cells using Western Blot Rabbit Aff - Purified Dros, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

COPS2 / TRIP15 antibody

Human, Mouse; . Sample Type: 1. Markers. 2. B8 mouse fibroblast cells, extraction only. 3. Human total cell extract. 4. Human blood cells, partially purified. 5. Pombe, extraction only. Primary Dilution: 1:200. Secondary Anitbody: HRP conjugated anti-rabbit. Image Submitted By: Dr. Elah Pick. University of Haifa at Oranim .; COPS2 antibody - N-terminal region (ARP34189_T100) in Human, Mouse cells using Western Blot Rabbit Aff - Purified African clawed frog, Bov, Can, Dros, Hu, Ms, Por, Rt, Ze WB
0.1 mg / €310.00
  AVIVA Systems Biology

COPS2 / TRIP15 antibody

Human Skin; COPS2 antibody - N-terminal region (ARP38431_T100) in Human Skin cells using Immunohistochemistry Rabbit Aff - Purified African clawed frog, Bov, Can, Chk, Hu, Ms, Por, Rt, Ze P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

COPS2 / TRIP15 antibody

Immunohistochemistry-Paraffin: COP9 signalosome complex subunit 2 Antibody [NB100-363] - FFPE section of human anaplastic thyroid carcinoma.  NB100-363 used at a dilution of 1:500.  DAB staining using Immunohistochemistry Accessory Kit Rabbit Purified Hu P, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

COPS2 / TRIP15 antibody

Western Blot: COP9 signalosome complex subunit 2 Antibody [NB100-364] - Whole cell lysate (50 mcg - E; 10 mcg - T) from mock transfected (E) or CSN2 transfected (T) HEK293T cells.  Antibody:  Affinity purified rabbit anti-CSN2 A300-028A used at the indicated concentration.  Detection: Chemiluminescence with a 30 second exposure. Rabbit Purified Hu WB
0.1 mg / €440.00
  Novus Biologicals Inc.

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