COPS7A antibody

Principal name

COPS7A antibody

Alternative names for COPS7A antibody

Signalosome subunit 7a, SGN7a, CSN7A, DERP10, COP9 signalosome complex subunit 7a, JAB1-containing signalosome subunit 7a, Dermal papilla-derived protein 10

SwissProt ID

Q9CZ04 (Mouse), Q9UBW8 (Human)

Gene ID

50813 (COPS7A)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Mky (Monkey), Can (Canine), Por (Porcine)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunoprecipitation (IP), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of COPS7A antibody

Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, JUN, I-kappa-B-alpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.

General readings

Wolf DA, Zhou C, et al. (2003). Nat Cell Biol. 5(12):1029-33.Wei N, Tsuge T, et al. (1998). Curr Biol. 8(16):919-22.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

COPS7A antibody

WB Suggested Anti-COPS7A Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1:312500; Positive Control: Human heart Rabbit IgG Purified Bov, Can, Hu, Por, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

COPS7A (C-term) antibody

COPS7A Antibody (C-term) (Cat. #AP51024PU-N)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of COPS7A Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

COPS7A antibody

Western Blot analysis of COPS7A expression in transfected 293T cell line (H00050813-T01) by COPS7A MaxPab polyclonal antibody.

Lane 1: COPS7A transfected lysate(30.25 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

COPS7A antibody

Mouse B8, Human HEK293; . Sample Type:.  1. Markers. . 2. B8 mouse fibroblast cells, extraction only. . 3. Human total cells, pure. Primary Dilution:.  1:500. Secondary Anitbody: . HRP conjugated anti-rabbit. Image Submitted By:.  Dr. Elah Pick. . University of Haifa at Oranim .; COPS7A antibody - middle region (ARP56886_P050) in Mouse B8, Human HEK293 cells using Western Blot Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

COPS7A antibody

Western blot analysis of COPS7A expression in JAR (A); HeLa (B); Raw264.7 (C); PC12 (D) whole cell lysates. Rabbit Aff - Purified Hu, Mky, Ms, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

COPS7A antibody

Western blot analysis of COPS7A expression in JAR (A); HeLa (B); Raw264.7 (C); PC12 (D) whole cell lysates. Rabbit Aff - Purified Hu, Mky, Ms, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

COPS7A antibody

Western blot analysis of COPS7A expression in JAR (A); HeLa (B); Raw264.7 (C); PC12 (D) whole cell lysates. Rabbit Aff - Purified Hu, Mky, Ms, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

COPS7A antibody

Western Blot: COPS7A Antibody [NBP1-53118] - This Anti-COPS7A antibody was used in Western Blot of Fetal Heart tissue lysate at a concentration of 1ug/ml. Rabbit Aff - Purified Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

COPS7A antibody

Immunohistochemistry-Paraffin: COPS7A Antibody [NBP1-84369] - Immunohistochemical staining of human pancreas shows distinct nuclear positivity in exocrine and islet cells. Rabbit IgG Aff - Purified Hu ICC/IF, P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

COPS7A

COPS7A Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

COPS7A (1-275, His-tag)

COPS7A Human Purified > 80 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

COPS7A (1-275, His-tag)

COPS7A Human Purified > 80 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

COPS7A

COPS7A Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

COPS7A 293T Cell Transient Overexpression Lysate(Denatured)

COPS7A 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

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