COPS8 antibody

Principal name

COPS8 antibody

Alternative names for COPS8 antibody

Signalosome subunit 8, SGN8, CSN8, COP9 signalosome complex subunit 8, JAB1-containing signalosome subunit 8

SwissProt ID

Q6P4Z9 (Rat), Q8VBV7 (Mouse), Q99627 (Human)

Gene ID

10920 (COPS8)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Paraffin Sections (P), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of COPS8 antibody

The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq]. Transcript Variant: This variant (2) contains an additional exon compared to variant 1, resulting in translation initiation from a downstream start codon and an isoform (2) with a shorter N-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

Lyapina S., et al. (2001) Science. 292:1382-5.Bech Otschir D., et al. (2001) EMBO J. 20:1630-9.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

COPS8 (C-term) antibody

Western blot analysis of CSN8 in Human liver lysate with CSN8 antibody at 2 µg/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

COPS8 antibody

WB Suggested Anti-COPS8 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: HepG2 cell lysateThere is BioGPS gene expression data showing that COPS8 is expressed in HepG2 Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

COPS8 (C-term) antibody

Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) Rabbit Hu, Ms, Rt P, WB
50 µg / €470.00
  Acris Antibodies GmbH

COPS8 Control Peptide

COPS8
50 µg / €160.00
  Acris Antibodies GmbH

COPS8 (N-term) antibody

COPS8 Antibody (N-term) (Cat. #AP51025PU-N) western blot analysis in Ramos cell line lysates (35µg/lane).This demonstrates the COPS8 antibody detected the COPS8 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

COPS8 antibody

Immunofluorescence of purified MaxPab antibody to COPS8 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Serum Hu, Rt E(detection), ICC/IF, WB
50 µl / €370.00
  Abnova Taiwan Corp.

COPS8 antibody

Immunofluorescence of purified MaxPab antibody to COPS8 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu, Rt E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

COPS8 antibody

Immunofluorescence of purified MaxPab antibody to COPS8 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

COPS8 antibody

Western Blot analysis of COPS8 expression in transfected 293T cell line by COPS8 monoclonal antibody (M04), clone 2G8.

Lane 1: COPS8 transfected lysate(23.2 KDa).
Lane 2: Non-transfected lysate. Mouse IgG2a 2G8 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

COPS8 antibody

Western blot analysis of COPS8 in human liver lysate with COPS8 polyclonal antibody ( Cat # PAB13034 ) at 2 µg/ml. Rabbit Hu, Ms, Rt WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

COPS8 (Center) antibody

Human, Mouse; . Sample Type:.  1. . B8 mouse fibroblast cells, extraction only. . 2. HEK 293 cells, extraction only. . 3. HEK 293 cells, purified. . 4. Human Blood cells, partially pure. 5. Human Blood cells, pure. 6. S. pombe, extraction only. Primary Dilution: 1:200. Secondary Anitbody: HRP conjugated anti-rabbit. Image Submitted By: Dr. Elah Pick. University of Haifa at Oranim .; COPS8 antibody - middle region (ARP52242_P050) in Human, Mouse cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

COPS8 antibody

COPS8 Rabbit Aff - Purified Hu, Ms, Rt P, WB
50 µg / €480.00
  Novus Biologicals Inc.

COPS8 antibody

Western Blot: COPS8 Antibody [NBP1-76373] - Analysis of CSN8 in Human liver lysate with CSN8 antibody at 2 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

COPS8 antibody

Immunohistochemistry-Paraffin: COPS8 Antibody [NBP1-84407] - Immunohistochemical staining of human cerebral cortex shows strong cytoplasmic positivity in astrocytes. Rabbit IgG Aff - Purified Hu ICC/IF, P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

COPS8 (transcript variant 2)

COPS8 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

COPS8 (full length, N-term HIS tag, transcript variant 1)

COPS8 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
E. coli
50 µg / €199.00
  OriGene Technologies, Inc.

COPS8 (1-209, His-tag)

COPS8 Human Purified > 90 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

COPS8 (1-209, His-tag)

COPS8 Human Purified > 90 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

COPS8 293T Cell Transient Overexpression Lysate(Denatured)

COPS8 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

COPS8 293T Cell Transient Overexpression Lysate(Denatured)

COPS8 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

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