Cortactin antibody
Principal name
Cortactin antibody
Alternative names for Cortactin antibody
CTTN, EMS1, Amplaxin, Oncogene EMS1
Available reactivities
Available hosts
Available applications
Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), EPair for Elisa (EPair), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP)
Background of Cortactin antibody
CTTN is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. CTTN is localized in the cytoplasm and in areas of the cell-substratum contacts. It has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, CTTN is degraded in a caspase-dependent manner. The aberrant regulation of t CTTN contributes to tumor cell invasion and metastasis.This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: (1) regulating the interactions between components of adherens-type junctions and (2) organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Two splice variants that encode different isoforms have been identified for this gene.
General readings
1. In J et al. Serine protease EspP from enterohemorrhagic Escherichia Coli is sufficient to induce shiga toxin macropinocytosis in intestinal epithelium. PLoS One 8:e69196 (2013).
2. Sheen-Chen SM et al. Cortactin in breast cancer: analysis with tissue microarray. Anticancer Res 31:293-7 (2011). IHC-P ; Human .
3. Miyaso H et al. The changes of cortactin p80/85 isoform profiles and tyrosine phosphorylation status during spermatogenesis in the mouse testis. J Androl 31:507-18 (2010).
4. Nieto-Pelegrin E & Martinez-Quiles N Distinct phosphorylation requirements regulate cortactin activation by TirEPEC and its binding to N-WASP. Cell Commun Signal 7:11 (2009). WB ; Mouse .










































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Primary Antibodies
Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
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TA302747 | Cortactin (N-term) antibody |
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Goat Polyclonal Antibody against CTTN | |||||||
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Goat | Aff - Purified | Bov, Can, Hu, Ms, Rt | WB |
0.1 mg /
€360.00
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OriGene Technologies, Inc. | |||||||
TA310011 | Cortactin antibody |
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Rabbit anti-CTTN (Cortactin, Phospho-Tyr466) polyclonal antibody(Phospho-specific) | |||||||
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Rabbit | IgG | Purified | Hu, Ms | WB |
0.1 mg /
€353.00
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OriGene Technologies, Inc. | |||||||
TA312466 | Cortactin antibody |
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Rabbit polyclonal Cortactin (Tyr466) antibody(Phospho-specific) | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | E, P, WB |
0.1 ml /
€335.00
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OriGene Technologies, Inc. | |||||||
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TA324049 | Cortactin antibody |
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Anti-CTTN (Phospho-Tyr466) Rabbit Polyclonal Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms | WB |
0.1 ml /
€335.00
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OriGene Technologies, Inc. | |||||||
TA324050 | Cortactin antibody |
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Anti-CTTN Rabbit Polyclonal Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | P, WB |
0.1 ml /
€335.00
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OriGene Technologies, Inc. | |||||||
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TA325399 | Cortactin antibody |
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Rabbit Polyclonal Cortactin Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | WB |
0.1 ml /
€335.00
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OriGene Technologies, Inc. | |||||||
TA325400 | Cortactin antibody |
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Rabbit Polyclonal Cortactin Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | WB |
0.1 ml /
€335.00
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OriGene Technologies, Inc. | |||||||
TA332919 | Cortactin antibody |
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Rabbit anti-CTTN Polyclonal Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt |
0.1 mg /
€335.00
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OriGene Technologies, Inc. | |||||||
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AM06601SU-N | Cortactin antibody |
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Mouse | IgG1 | 4C6 | Ascites | Hu, Ms | E, P, WB |
0.1 ml /
€430.00
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Acris Antibodies GmbH | |||||||
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AP02517PU-N | Cortactin pTyr466 antibody |
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Rabbit | Aff - Purified | Ms | WB |
0.1 mg /
€320.00
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Acris Antibodies GmbH | |||||||
AP02517PU-S | Cortactin pTyr466 antibody |
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Rabbit | Aff - Purified | Ms | WB |
50 µg /
€240.00
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Acris Antibodies GmbH | |||||||
AP02764PU-N | Cortactin antibody |
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Rabbit | Aff - Purified | Ms | P |
0.1 mg /
€320.00
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Acris Antibodies GmbH | |||||||
AP02764PU-S | Cortactin antibody |
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Rabbit | Aff - Purified | Ms | P |
50 µg /
€240.00
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Acris Antibodies GmbH | |||||||
AP02765PU-N | Cortactin antibody |
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Rabbit | Aff - Purified | Ms | P, WB |
0.1 mg /
€320.00
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Acris Antibodies GmbH | |||||||
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AP02765PU-S | Cortactin antibody |
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Rabbit | Aff - Purified | Ms | P, WB |
50 µg /
€240.00
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Acris Antibodies GmbH | |||||||
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AP20737PU-N | Cortactin antibody |
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Rabbit | Aff - Purified | Hu, Ms, Rt | P, WB |
0.1 mg /
€350.00
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Acris Antibodies GmbH | |||||||
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AP20738PU-N | Cortactin antibody |
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Rabbit | Aff - Purified | Hu, Ms | ICC/IF, P, WB |
0.1 mg /
€350.00
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Acris Antibodies GmbH | |||||||
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AP20857PU-N | Cortactin pTyr421 antibody |
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Rabbit | Aff - Purified | Hu, Ms, Rt | P, WB |
0.1 mg /
€350.00
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Acris Antibodies GmbH | |||||||
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AP54041PU-N | Cortactin (N-term) antibody |
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Rabbit | Ig | Aff - Purified | Hu | P, WB |
0.4 ml /
€370.00
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Acris Antibodies GmbH | |||||||
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A7049-1 | Cortactin pTyr421 antibody |
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Rabbit | Aff - Purified | Hu, Ms, Rt | E, WB |
50 µg /
€230.00
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Assay Biotech |