CPEB1 antibody

Principal name

CPEB1 antibody

Alternative names for CPEB1 antibody

CPE-binding protein 1, CPE-BP1, hCPEB-1, h-CEBP, Cytoplasmic polyadenylation element-binding protein 1

SwissProt ID

P0C279 (Rat), P70166 (Mouse), Q9BZB8 (Human)

Gene ID

64506 (CPEB1), 3645061 (ATG4)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Macaque, Bov (Bovine)

Available hosts

Rabbit, Goat, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P), ELISA (detection) (E(detection))

Background of CPEB1 antibody

The regulated translation of messenger RNA is essential for cell-cycle progression, establishment of the body plan during early development, and modulation of key activities in the central nervous system. Cytoplasmic polyadenylation, which is one mechanism of controlling translation, is driven by CPEB (cytoplasmic polyadenylation element binding protein), a highly conserved, sequence-specific RNA-binding protein that binds to the cytoplasmic polyadenylation element, and modulates translational repression and mRNA localization. In both vertebrates and invertebrates, the expression of several maternal mRNAs is regulated by cytoplasmic polyadenylation. In Xenopus oocytes, where most of the biochemical details of this process have been examined, polyadenylation is controlled by CPEB.
Early metazoan development is programmed by maternal mRNAs inherited by the egg at the time of fertilization. These mRNAs are not translated en masse at any one time or at any one place, but instead their expression is regulated both temporally and spatially. Mammalian neurons, particularly in the synapto-dendritic compartment, also contain localized mRNAs such as that encoding alpha-CaMKII. Here, synaptic activation drives local translation, an event that is involved in synaptic plasticity and possibly long-term memory storage. Synaptic translation of alpha-CaMKII mRNA also appears to be controlled by CPEB, which is enriched in the postsynaptic density. Therefore, CPEB-controlled local translation may influence such seemingly disparate processes as the cell cycle and synaptic plasticity.

General readings

1. Welk JF, Charlesworth A, Smith GD, MacNicol AM.
Identification and characterization of the gene encoding human cytoplasmic polyadenylation element binding protein.
Gene. 2001 Jan 24;263(1-2):113-20. PMID: 11223249.

Items 1 to 20 of 24 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CPEB1 antibody

TA302946 staining (0.5µg/ml) of human brain lysate (RIPA buffer, 35µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Hu, Macaque WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CPEB1 (N-term) antibody

Western blot analysis of CPEB1 in rat brain tissue lysate with CPEB1 antibody at (A) 1 and (B) 2 µg/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CPEB1 Control Peptide

CPEB1
50 µg / €160.00
  Acris Antibodies GmbH

CPEB1 (C-term) antibody

Western blot analysis of CPEB1 Antibody (C-term) Cat.-No AP51048PU-N in A2058 cell line lysates (35ug/lane).This demonstrates the CPEB1 antibody detected the CPEB1 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CPEB1 antibody

Western Blot analysis of CPEB1 expression in transfected 293T cell line (H00064506-T01) by CPEB1 MaxPab polyclonal antibody.

Lane 1: CPEB1 transfected lysate(53.46 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

CPEB1 antibody

CPEB1 Rabbit Purified Hu, Ms E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

CPEB1 antibody

CPEB1 polyclonal antibody ( Cat # PAB6644 ) staining ( 0.5 µg/ml ) of human brain lysate ( RIPA buffer, 35 µg total protein per lane ) . Primary incubated for 1 hour. Detected by western blot using chemiluminescence. Goat Hu E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

CPEB1 antibody

Western blot analysis of CPEB1 in rat brain tissue lysate with CPEB1 polyclonal antibody ( Cat # PAB13049 ) at ( A ) 1 and ( B ) 2 µg/ml. Rabbit Hu, Ms, Rt WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

CPEB1 antibody

NB 100-1437 staining (0.5µg/ml) of Human Brain lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence Goat IgG Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €400.00
  Novus Biologicals Inc.

CPEB1 antibody

Western Blot: CPEB1 Antibody [NBP1-76365] - Analysis of CPEB1 in rat brain tissue lysate with CPEB1 antibody at (A) 1 and (B) 2 ug/mL._x000d_ Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CPEB1 (transcript variant 3)

CPEB1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

CPEB1 (transcript variant 4)

CPEB1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

CPEB1 (1-561, His-tag)

CPEB1 Human Purified > 85 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

CPEB1 (1-561, His-tag)

CPEB1 Human Purified > 85 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

CPEB1

CPEB1 Human
2 µg / €300.00
  Abnova Taiwan Corp.

CPEB1

CPEB1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

CPEB1

CPEB1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

CPEB1

CPEB1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

CPEB1

CPEB1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

CPEB1 293T Cell Transient Overexpression Lysate(Denatured)

CPEB1 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

Items 1 to 20 of 24 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn