CPEB1 antibody

Principal name

CPEB1 antibody

Alternative names for CPEB1 antibody

CPE-binding protein 1, CPE-BP1, hCPEB-1, h-CEBP, Cytoplasmic polyadenylation element-binding protein 1

SwissProt ID

P0C279 (Rat), P70166 (Mouse), Q9BZB8 (Human)

Gene ID

64506 (CPEB1), 12877 (Cpeb1), 293056

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Macaque

Available hosts

Rabbit, Mouse, Goat

Available applications

Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Enzyme Immunoassay (E)

Background of CPEB1 antibody

The regulated translation of messenger RNA is essential for cell cycle progression, establishment of the body plan during early development, and modulation of key activities in the central nervous system. Cytoplasmic polyadenylation, which is one mechanism of controlling translation, is driven by CPEB1 (Cytoplasmic Polyadenylation Element Binding protein), a highly conserved, sequence specific RNA binding protein that binds to the cytoplasmic polyadenylation element (CPE) and modulates translational repression and mRNA localisation. CPEB1 can assemble bothe translational activation and repression complexes via its binding to the CPE. In both vertebrates and invertebrates, the expression of several maternal mRNAs is regulated by cytoplasmic polyadenylation. In Xenopus oocytes, where most of the biochemical details of this process have been examined, polyadenylation is controlled by CPEB1.

General readings

1. Welk JF, Charlesworth A, Smith GD, MacNicol AM.
Identification and characterization of the gene encoding human cytoplasmic polyadenylation element binding protein.
Gene. 2001 Jan 24;263(1-2):113-20. PMID: 11223249.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CPEB1 antibody

  Goat Polyclonal Antibody against CPEB1  
TA302946 staining (0.5µg/ml) of human brain lysate (RIPA buffer, 35µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Hu, Macaque WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CPEB1 (N-term) antibody

  Rabbit Polyclonal CPEB1 Antibody  
Western blot analysis of CPEB1 in rat brain tissue lysate with CPEB1 antibody at (A) 1 and (B) 2 µg/ml. Rabbit IgG Aff - Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CPEB1 (C-term) antibody

Western blot analysis of CPEB1 Antibody (C-term) Cat.-No AP51048PU-N in A2058 cell line lysates (35ug/lane).This demonstrates the CPEB1 antibody detected the CPEB1 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

CPEB1 - human gene knockout kit via CRISPR

CPEB1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

CPEB1 - human gene knockout kit via CRISPR

CPEB1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CPEB1 - human gene knockout kit via CRISPR

CPEB1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CPEB1 - human gene knockout kit via CRISPR

CPEB1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cpeb1 - mouse gene knockout kit via CRISPR

Cpeb1 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Cpeb1 - mouse gene knockout kit via CRISPR

Cpeb1 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cpeb1 - mouse gene knockout kit via CRISPR

Cpeb1 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cpeb1 - mouse gene knockout kit via CRISPR

Cpeb1 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CPEB1 (transcript variant 3)

  Recombinant protein of human cytoplasmic polyadenylation element binding protein 1 (CPEB1), transcript variant 3  
CPEB1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

CPEB1 (transcript variant 4)

  Recombinant protein of human cytoplasmic polyadenylation element binding protein 1 (CPEB1), transcript variant 4  
CPEB1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

CPEB1 (1-561, His-tag)

CPEB1 Human Purified > 85 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

CPEB1 (1-561, His-tag)

CPEB1 Human Purified > 85 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

Lysates

Catalog No.    

CPEB1 overexpression lysate

CPEB1 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

CPEB1 overexpression lysate

CPEB1 overexpression lysate  
0.1 mg / €480.00
  OriGene Technologies, Inc.

CPEB1 overexpression lysate

CPEB1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

CPEB1 overexpression lysate

CPEB1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, CPEB1 (mGFP-tagged) - Human cytoplasmic polyadenylation element binding protein 1 (CPEB1), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, CPEB1 (mGFP-tagged) - Human cytoplasmic polyadenylation element binding protein 1 (CPEB1), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

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