CPOX antibody

Principal name

CPOX antibody

Alternative names for CPOX antibody

Coproporphyrinogenase, Coprogen oxidase, CPO, CPX, mitochondrial Coproporphyrinogen III oxidase

SwissProt ID

P36551 (Human), P36552 (Mouse), Q3B7D0 (Rat)

Gene ID

1371 (CPOX)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunoprecipitation (IP), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of CPOX antibody

CPOX is a 454 amino acid mitochondrial enzyme that is localized to the inner membrane space of erythrocytes. It participates in the sixth step of heme biosynthesis by catalyzing the formation of protoporphyrinogen IX from copropophyrinogen III. Mutations in the gene encoding CPOX are the cause of coproporphyria, an autosomal dominant disease characterized by skin photosensitivity and neurological disturbances. Symptoms are often experienced as attacks, which include severe abdominal and nerve pain. People affected by coproporphyria overexcrete copropophyrinogen III in feces and urine and the enzymatic activity of CPOX is found to be approximately half that of normal, leading to a decrease in overall heme synthesis. There is no cure for coproporphyria, but preventative treatment to relieve symptoms usually involves dietary changes and avoidance of drugs and alcohol.

General readings

Martasek P., et al. (1994) Hum Mol Genet. 3:477-480Lamoril J., et al. (1995) Hum Mol Genet. 4:275-278.

8 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CPOX antibody

Sample (30 ug of whole cell lysate). A: HCT116 10% SDS PAGE. TA308010 diluted at 1:1000. Rabbit IgG Aff - Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CPOX antibody

Western  Blot:  CPOX Antibody [NBP1-33665] – Western blot analysis of CPOX on HCT116 lysates using NBP1-33665 at a dilution of 1:1000. 30ug whole cell lysate loaded on 10% SDS PAGE gel. Rabbit IgG Hu WB
0.1 ml / €420.00
  Novus Biologicals Inc.

CPOX antibody

Immunohistochemistry-Paraffin: CPOX Antibody [NBP1-85479] -  staining of human skeletal muscle shows strong cytoplasmic positivity in myocytes. Rabbit IgG Aff - Purified Hu ICC/IF, P, WB
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CPOX (111-454, His-tag)

CPOX Human Purified > 95 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

CPOX (111-454, His-tag)

CPOX Human Purified > 95 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

CPOX

CPOX Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

CPOX

CPOX Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

CPOX

CPOX Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

8 Item(s)

per page
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