CPSF4 antibody

Principal name

CPSF4 antibody

Alternative names for CPSF4 antibody

CPSF30, NAR, NEB1, No arches homolog, Cleavage and polyadenylation specificity factor subunit 4, Cleavage and polyadenylation specificity factor 30 kDa subunit, NS1 effector domain-binding protein 1

SwissProt ID

O19137 (Bovin), O95639 (Human), Q5FVR7 (Rat), Q8BQZ5 (Mouse)

Gene ID

10898 (CPSF4), 7108985 (acpP)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Chk (Chicken), Rt (Rat), Eq (Equine), GP (Guinea Pig), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

ELISA (detection) (E(detection)), Western blot / Immunoblot (WB), Immunoprecipitation (IP), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P)

Background of CPSF4 antibody

Inhibition of the nuclear export of poly(A)-containing mRNAs caused by the influenza A virus NS1 protein requires its effector domain. The NS1 effector domain functionally interacts with the cellular 30 kDa subunit of cleavage and polyadenylation specific factor 4, an essential component of the 3' end processing machinery of cellular pre-mRNAs. In influenza virus-infected cells, the NS1 protein is physically associated with cleavage and polyadenylation specific factor 4, 30kD subunit. Binding of the NS1 protein to the 30 kDa protein in vitro prevents CPSF binding to the RNA substrate and inhibits 3' end cleavage and polyadenylation of host pre-mRNAs. Thus the NS1 protein selectively inhibits the nuclear export of cellular, and not viral, mRNAs. Multiple alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq]. Transcript Variant: This variant (2) uses an alternate in-frame splice site in the 3' coding region, compared to variant 1, resulting in a shorter protein (isoform 2).

General readings

Jenny,A., et al. (1994) Mol. Cell. Biol. 14 (12), 8183-8190Barabino,S.M., et al. (1997) Nephrol Genes Dev. 11 (13), 1703-1716

19 Item(s)

per page

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CPSF4 antibody

WB Suggested Anti-CPSF4 Antibody Titration: 0.2-1 ug/ml; Positive Control: Jurkat cell lysateCPSF4 is supported by BioGPS gene expression data to be expressed in Jurkat Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt WB
50 µg / €325.00
  OriGene Technologies, Inc.

CPSF4 (Center) antibody

Western blot analysis of CPSF4 Antibody (Center) Cat.-No AP51059PU-N in Jurkat cell line lysates (35ug/lane).CPSF4 (arrow) was detected using the purified Pab. Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CPSF4 antibody

Western Blot analysis of CPSF4 expression in transfected 293T cell line (H00010898-T01) by CPSF4 MaxPab polyclonal antibody.

Lane 1: CPSF4 transfected lysate(26.95 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

CPSF4 antibody

Western Blot analysis of CPSF4 expression in transfected 293T cell line (H00010898-T02) by CPSF4 MaxPab polyclonal antibody.

Lane 1: CPSF4 transfected lysate(26.73 KDa).
Lane 2: Non-transfected lysate. Mouse Serum Hu E(detection), WB
50 µl / €370.00
  Abnova Taiwan Corp.

CPSF4 antibody

Western Blot analysis of CPSF4 expression in transfected 293T cell line (H00010898-T03) by CPSF4 MaxPab polyclonal antibody.

Lane 1: CPSF4 transfected lysate(26.73 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

CPSF4 antibody

Human Jurkat; WB Suggested Anti-CPSF4 Antibody Titration: 0.2-1 ug/ml. Positive Control: Jurkat cell lysate. CPSF4 is supported by BioGPS gene expression data to be expressed in Jurkat.; CPSF4 antibody - C-terminal region (ARP40675_P050) in Human Jurkat cells using Western Blot Rabbit Purified Bov, Can, Chk, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

CPSF4 antibody

Western Blot and  Immunoprecipitation: CPSF30 Antibody [NB100-79826] - Detection of Human and Mouse CPSF30 on HeLa whole cell lysate using NB100-79826. CPSF30 was also immunoprecipitated by rabbit anti-CPSF30 antibody NB10-79827. Rabbit IgG Aff - Purified Hu, Ms IP, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

CPSF4 antibody

Western Blot and  Immunoprecipitation: CPSF30 Antibody [NB100-79827] - Detection of Human and Mouse CPSF30 on HeLa whole cell lysate using NB100-79827. CPSF30 was also immunoprecipitated by rabbit anti-CPSF30 antibody NB100-79826. Rabbit IgG Aff - Purified Hu, Ms IP, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

CPSF4 antibody

Western Blot: CPSF4 Antibody [NBP1-57114] - This Anti-CPSF4 antibody was used in Western Blot of Jurkat tissue lysate at a concentration of 0.5ug/ml. Rabbit Aff - Purified Can, Hu, Ms, Rt WB
50 µg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CPSF4 (1-244, His-tag)

CPSF4 Human Purified > 85 % by SDS - PAGE E. coli
0.5 mg / €730.00
  Acris Antibodies GmbH

CPSF4 (1-244, His-tag)

CPSF4 Human Purified > 85 % by SDS - PAGE E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

CPSF4

CPSF4 Human
2 µg / €300.00
  Abnova Taiwan Corp.

CPSF4

CPSF4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

CPSF4

CPSF4 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

CPSF4 293T Cell Transient Overexpression Lysate(Denatured)

CPSF4 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

CPSF4 293T Cell Transient Overexpression Lysate(Denatured)

CPSF4 293T Cell Transient Overexpression Lysate(Denatured)  
0.1 ml / €270.00
  Abnova Taiwan Corp.

CPSF4 overexpression lysate

CPSF4 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

CPSF4 overexpression lysate

CPSF4 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

CPSF4 overexpression lysate

CPSF4 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

19 Item(s)

per page
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