CPT1C / CPT1-B antibody

Principal name

CPT1C / CPT1-B antibody

Alternative names for CPT1C / CPT1-B antibody

Carnitine palmitoyltransferase 1C, CPT IC, Carnitine O-palmitoyltransferase 1, brain isoform

SwissProt ID

Q8BGD5 (Mouse), Q8TCG5 (Human)

Gene ID

126129 (CPT1C)

Available reactivities

Bov (Bovine), Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat), Por (Porcine)

Available hosts

Goat, Rabbit, Mouse

Available applications

Western blot / Immunoblot (WB), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Paraffin Sections (P), Flow Cytometry (F)

Background of CPT1C / CPT1-B antibody

The Cpt1 family of proteins are outer mitochondrial membrane proteins that regulate the entry into, and oxidation of fatty acids by, mitochondria. Malonyl-CoA, an intermediate in fatty acid synthesis, has been implicated as a regulatory component of the energy sensing system that feeds into hypothalmic neurons to impart energy homeostasis. Malonyl-CoA levels in the hypothalamus are dynamically regulated by fasting and feeding, altering subsequent feeding behaviour. Cpt1c, the brain-specific carnitine O-palmitoyltransferase 1, is thought to relay information about malonyl-CoA levels in hypothalamic neurons that express orexigenic and anorexigenic neuropeptides that regulate food intake and peripheral energy expenditure. Unlike other Cpt1 proteins, Cpt1c binds Malonyl-CoA but does not catalyse the transfer of the malonyl group from CoA to carnitine.

General readings

Sierra AY, Gratacós E, Carrasco P, Clotet J, Ureña J, Serra D, Asins G, Hegardt FG, Casals N.
CPT1c is localized in endoplasmic reticulum of neurons and has carnitine palmitoyltransferase activity.
J Biol Chem. 2008 Mar 14;283(11):6878-85. Epub 2008 Jan 11.
PMID: 18192268

5 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CPT1C / CPT1-B antibody

(1ug/ml) staining of Human Frontal Cortex lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CPT1C / CPT1-B (C-term) antibody

CPT1C Antibody (C-term) (Cat. #AP51064PU-N) western blot analysis in HL-60 cell line lysates (35µg/lane).This demonstrates the CPT1C antibody detected the CPT1C protein (arrow). Rabbit Ig Aff - Purified Hu F, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CPT1C / CPT1-B (C-term) antibody

Western blot analysis of CPT1C Antibody (C-term) Cat.-No AP51065PU-N in HL-60 cell line lysates (35ug/lane).This demonstrates the CPT1C antibody detected the CPT1C protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CPT1C / CPT1-B (transcript variant 2)

CPT1C / CPT1-B Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.


CPT1C / CPT1-B Human
2 µg / €300.00
  Abnova Taiwan Corp.

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