CRABP1 antibody

Principal name

CRABP1 antibody

Alternative names for CRABP1 antibody

CRABP-I, RBP5, Cellular retinoic acid-binding protein 1, Cellular retinoic acid-binding protein I

SwissProt ID

P29762 (Human), P40220 (Chick), P62964 (Bovin), P62965 (Mouse), P62966 (Rat)

Gene ID

1381 (CRABP1)

Available reactivities

Bov (Bovine), Chk (Chicken), Fe (Feline), Hu (Human), Prim (Primate), Rb (Rabbit), Re (Reptiles), Rt (Rat), Can (Canine), Mky (Monkey), Ms (Mouse)

Available hosts

Mouse, Rabbit

Available applications

Frozen Sections (C), Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P)

Background of CRABP1 antibody

Retinoic acid (RA), a metabolite of vitamin A, plays an important role in growth and differentiation by modulation of expression of certain genes. RA functions through its interaction with the nuclear protein, retinoic acid receptor (RAR) and the 9-cis RA with retinoid X receptor (RXR). The cellular retinoic acid binding proteins (CRABP) bind RA with a high affinity and belong to the family of fatty acid binding proteins.
Two forms of CRABP have been characterized, CRABPI and CRABPII which share ~75% sequence conservation. The main role of CRABPI may be to protect retinoids from non-specific dehydrogenases and direct them to specific enzymes. The precise role of CRABPII is still poorly understood but it seems to play a role in the interaction of ligands (RA, 9-cis RA) with nuclear receptors (RAR/RXR).

General readings

Kelley MW et al. Retinoic acid promotes differentiation of photoreceptors in vitro. Development 120:2091-102 (1994). PubMed PMID: 7925013
Kelley MW et al. The developing organ of Corti contains retinoic acid and forms supernumerary hair cells in response to exogenous retinoic acid in culture. Development 119:1041-53 (1993). PubMed PMID: 8306874
Gaur VP et al. Localization of cellular retinoic acid-binding protein to amacrine cells of rat retina. Exp Eye Res 50:505-11 (1990). PubMed PMID: 2164945
Milam AH et al. Immunolocalization of cellular retinoic acid binding protein to Muller cells and/or a subpopulation of GABA-positive amacrine cells in retinas of different species. J Comp Neurol 296:123-9 (1990). PubMed PMID: 2162866
De Leeuw AM et al. Immunolocalization of cellular retinol-, retinaldehyde- and retinoic acid-binding proteins in rat retina during pre- and postnatal development. J Neurocytol 19:253-64 (1990). PubMed PMID: 2162910

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CRABP1 antibody

Immunohistochemistry: AM09092PU-N CRABP1 antibody staining of Formalin-Fixed, Paraffin-Embedded Human  Thyroid followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen. Mouse IgG2b AT1A1 Purified Hu, Ms E, P, WB
0.1 ml / €310.00
  Acris Antibodies GmbH

CRABP1 antibody

Immunohistochemistry: AM09092PU-N CRABP1 antibody staining of Formalin-Fixed, Paraffin-Embedded Human  Thyroid followed by biotinylated secondary antibody, alkaline phosphatase-streptavidin and chromogen. Mouse IgG2b AT1A1 Purified Hu, Ms E, P, WB
50 µl / €230.00
  Acris Antibodies GmbH

CRABP1 antibody

CRABP1 Mouse IgG2b C-1 Ascites Bov, Can, Chk, Fe, Hu, Mky, Rb, Rt C, E, P, WB
0.1 ml / €400.00
  Novus Biologicals Inc.

CRABP1 antibody

CRABP1 Mouse IgG2b AT1A1 Hu E, WB
0.1 ml / €380.00
  Novus Biologicals Inc.

CRABP1 antibody

Immunohistochemistry-Paraffin: CRABP1 Antibody [NBP1-84384] Immunohistochemical staining of human esophagus shows strong cytoplasmic positivity in squamous epithelial cells. Rabbit IgG Aff - Purified Hu P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CRABP1 (1-137)

CRABP1 Human Purified > 95 % by SDS - PAGE E. coli
0.5 mg / €990.00
  Acris Antibodies GmbH

CRABP1 (1-137)

CRABP1 Human Purified > 95 % by SDS - PAGE E. coli
0.1 mg / €370.00
  Acris Antibodies GmbH

CRABP1

CRABP1 Human
2 µg / €300.00
  Abnova Taiwan Corp.

CRABP1

CRABP1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

CRABP1

CRABP1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

CRABP1

CRABP1 Human Purified
10 µg / €380.00
  Abnova Taiwan Corp.

CRABP1

CRABP1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

CRABP1

CRABP1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

CRABP1

SDS-Page: CRABP1 Protein [NBP1-30183] - CRABP1,15.5 kDa (137 aa), confirmed by MALDI-TOF with a purity of 95% by SDS - PAGE
0.1 mg / €440.00
  Novus Biologicals Inc.

14 Item(s)

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