CRHR2 antibody

Principal name

CRHR2 antibody

Alternative names for CRHR2 antibody

Corticotropin-releasing factor receptor 2, CRF-R 2, CRF2, CRF2R, CRH2R, Corticotropin-releasing hormone receptor 2

SwissProt ID

O42603 (Xenla), P47866 (Rat), Q13324 (Human), Q60748 (Mouse)

Gene ID

1395 (CRHR2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Por (Porcine), Bov (Bovine), Can (Canine), Chk (Chicken), Eq (Equine), Hst (Hamster), Mky (Monkey), Rb (Rabbit)

Available hosts

Rabbit, Mouse

Available applications

Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Flow Cytometry (F), Paraffin Sections (P), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Immunoprecipitation (IP)

Background of CRHR2 antibody

Individuals suffering from Alzheimer's disease (AD) exhibit dramatic reductions in the content of corticotropin-releasing factor (CRF), increased expression of CRF receptors (CRFRs) and abnormalities in neuronal morphology in affected brain areas. In addition, AD patients show decreased concentrations of CRF in their cerebrospinal fluid, which may contribute to their cognitive impairment. A high affinity CRF binding protein, designated CRF-BP, has been discovered in postmortem brain samples from AD patients. CRF-BP serves to bind and inactivate CRF, reducing the pool of ''free CRF'' available to bind CRFRs. Two CRF receptors, designated CRF-RI and CFR-RII, exhibit distinct brain localizations. Two forms of CFR-RII, designated CFR-RIIalpha and CFR-RIIbeta, result from alternative mRNA splicing. Urocortin, an additional member of the CRF family, shares 63% sequence identity with urotensin and 45% sequence identity with CRF. Urocortin specifically binds to and activates CRF-RI and CRF-RII, but binds to CRF-RII more efficiently than CRF, suggesting that it may be the true, high affinity ligand for the CRF receptor type II.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CRHR2 (N-term, Extracell. Dom.) antibody

Anti-CRHR2 antibody IHC of human brain, pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Bear, Bov, Can, Chk, Elephant, Eq, Fi, Hu, L, Mky, Ms, Op, Por, Prim, Rb, Rt, Tr P, WB
50 µg / €379.00
  OriGene Technologies, Inc.

CRHR2 antibody

Anti-CRHR2 / CRF2 Receptor antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Hu, Ms, Rt P
50 µg / €379.00
  OriGene Technologies, Inc.

CRHR2 antibody

Anti-CRHR2 / CRF2 Receptor antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Bov, Can, Hu, Ms, Por, Rb
50 µg / €379.00
  OriGene Technologies, Inc.

CRHR2 antibody

Western blot analysis of extracts from COLO205 cells and RAW264.7 cells, using CRHR2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CRHR2 antibody

Western blot analysis of extracts from K562 cells, LOVO cells, 3T3 cells and RAW264.7 cells, using CRFR2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CRHR2 antibody

Western Blot: Corticotropin Releasing Factor Receptor 2 Antibody [TA336366] - analysis ofCRHR2 inhuman brainlysate in the 1) absence and 2) presence of immunizing peptide using this antibody. Both of the isoforms detected by this antibody. Rabbit Purified Bov, Can, Chk, Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CRHR2 (1st Extracell. Dom.) antibody

Anti-CRHR2 antibody IHC of human brain, choroid plexus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Aff - Purified Bear, Bov, Bt, Can, Elephant, Eq, Hst, Hu, Ms, Por, Rb, Rt P
50 µg / €379.00
  OriGene Technologies, Inc.

CRHR2 antibody

Anti-CRHR2 antibody IHC of human brain. pituitary. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Rabbit Purified Hu
50 µg / €379.00
  OriGene Technologies, Inc.

CRHR2 antibody

Western blot analysis of CRFR2 expression in K562 cells Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CRHR2 antibody

Western blot (WB) analysis of CRF-RII antibody (Cat.-No. AP01195PU-N) in extracts from COLO205 cells. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CRHR2 antibody

Western blot (WB) analysis of CRF-RII antibody (Cat.-No.: AP01213PU-N) in extracts from K562 cells. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CRHR2 antibody

Western blot analysis of CRHR2 Antibody (Center) (AP17244PU-N) in Hela cell line lysates (35 µg/lane). CRHR2 (arrow) was detected using the purified Pab. Rabbit Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRHR2 (N-term) antibody

Western blot analysis of CRHR2 Antibody (N-term) (AP17245PU-N) in NIH-3T3 cell line lysates (35 µg/lane). CRHR2 (arrow) was detected using the purified Pab. Rabbit Hu, Ms WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRHR2 antibody

Immunohistochemical staining of Formalin-Fixed, Paraffin-Embedded human adrenal tissue using anti-CRF-R2 antibody cat. no. AP39031PU-N Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CRHR2 antibody

CRFR2 Antibody (D35)(Cat. #AP51079PU-N)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CRFR2 Antibody (D35) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRHR2 antibody

Imunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue using CRFR2D Antibody Cat.-No AP51080PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of CRFR2D Antibody for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu F, P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CRHR2 antibody

Western Blot analysis of CRHR2 expression in transfected 293T cell line (H00001395-T01) by CRHR2 MaxPab polyclonal antibody.

Lane 1: CRHR2 transfected lysate(45.21 KDa).
Lane 2: Non-transfected lysate. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

CRHR2 antibody

Immunofluorescence analysis of MCF7 cells, using CRHR2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
50 µg / €205.00
  Assay Biotech

CRHR2 antibody

Immunofluorescence analysis of MCF7 cells, using CRHR2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, WB
0.1 mg / €310.00
  Assay Biotech

CRHR2 antibody

Western blot analysis of extracts from K562/LOVO/NIH-3T3/RAW264.7 cells, using CRFR2 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €205.00
  Assay Biotech

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