CRKL antibody

Principal name

CRKL antibody

Alternative names for CRKL antibody

Crk-like protein, v-crk avian sarcoma virus CT10 oncogene homolog-like

SwissProt ID

P46109 (Human), P47941 (Mouse)

Gene ID

1399 (CRKL), 3667 (IRS1)

Available reactivities

Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Goat, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Dot blot (Dot), Frozen Sections (C), Flow Cytometry (F), Immunoprecipitation (IP)

Background of CRKL antibody

SH2 and SH3 (Src homology) domains were originally identified as critical functional domains within non-receptor proteins with tyrosine kinase activity. A subset of these proteins appears to exist predominately of SH2/SH3 domains in the absence of detectable catalytic domains. One of the first members of the family to be identified, Crk, is a transformation-specific protein that induces elevation of cellular phosphotyrosine levels, but lacks tyrosine kinase activity itself. A second protein, Nck, consists solely of three SH3 domains and one SH2 domain, while GRB2 contains an SH2 domain flanked on both sides by SH3 domains. A member of this protein class, Crk-L, is encoded by a gene located on chromosome 22, band 11, centromeric of the chronic myelogenous leukemia breakpoint region. Crk-L encodes a 303 amino acid protein with one SH2 and two SH3 domains, and a predicted molecular weight of 36 kDa.

General readings

General / background references: Senechal K et al. The CRKL adaptor protein transforms fibroblasts and functions in transformation by the BCR-ABL oncogene. J Biol Chem 271:23255-61 (1996). PubMed: 8798523. Search PubMed (MEDLINE) for references to CrkL

  1. Quick-Filters:
  2. Highly Validated (2)

Items 1 to 20 of 35 total

per page
Page:
  1. 1
  2. 2

Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CRKL antibody

Proximity Ligation Analysis (PLA) of protein-protein interactions between CRKL and PTPN11. Mahlavu cells were stained with anti-CRKL rabbit purified polyclonal 1:600 and anti-PTPN11 mouse purified polyclonal antibody 1:100. Signals were detected by Duolink® 30 Detection Kit 613(red), and nuclei were counterstained with DAPI (blue). Each red dot represents the detection of protein-protein interaction complex. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

CRKL antibody

Proximity Ligation Analysis (PLA) of protein-protein interactions between HCK and CRKL Mahlavu cells were stained with anti-HCK rabbit purified polyclonal 1:1200 and anti-CRKL mouse monoclonal antibody 1:50. Signals were detected by Duolink® 30 Detection Kit 613(red), and nuclei were counterstained with DAPI (blue). Each red dot represents the detection of protein-protein interaction complex. Mouse IgG2b 4B5 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CRKL (C-term) antibody

TA302748 (0.01µg/ml) staining of K562 lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu, Ms, Rt E, WB
20 µg / €200.00
  Acris Antibodies GmbH

CRKL (C-term) antibody

TA302748 (0.01µg/ml) staining of K562 lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CRKL antibody

WB Suggested Anti-CRKL Antibody Titration: 0.2-1 ug/ml; Positive Control: K562 cell lysate CRKL is strongly supported by BioGPS gene expression data to be expressed in Human K562 cells Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

CRKL antibody

Western blot analysis using CRKL mAb against human CRKL (AA: 100-303) recombinant protein. (Expected MW is 60 kDa) Mouse IgG1 5E12 Ascites Hu E, WB
0.1 ml / €430.00
  Acris Antibodies GmbH

CRKL antibody

Immunohistochemistry analyzes of CrkL antibody (AP20279PU-N) in paraffin-embedded human lung carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CRKL pTyr207 antibody

Immunohistochemistry (IHC) analyzes of p-CrkL (Try207) antibody (Cat.-No.: AP20935PU-N) in paraffin-embedded human lung adenocarcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P
0.1 mg / €350.00
  Acris Antibodies GmbH

CRKL antibody

Immunohistochemistry (IHC) analyzes of CrkL antibody (Cat.-No.: AP21023PU-N) in paraffin-embedded human lung adenocarcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P
0.1 mg / €350.00
  Acris Antibodies GmbH

CRKL antibody

CRKL Goat Purified Hu, Ms WB
0.1 mg / €550.00
  Acris Antibodies GmbH

CRKL antibody

CRKL Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

CRKL antibody

Immunofluorescence of purified MaxPab antibody to CRKL on HeLa cell. [antibody concentration 10 ug/ml] Mouse Serum Hu E(detection), ICC/IF, WB
50 µl / €370.00
  Abnova Taiwan Corp.

CRKL antibody

Immunofluorescence of purified MaxPab antibody to CRKL on HeLa cell. [antibody concentration 10 ug/ml] Mouse Purified Hu E(detection), ICC/IF, WB
50 µg / €370.00
  Abnova Taiwan Corp.

CRKL antibody

CRKL polyclonal antibody ( Cat # PAB6084 ) staining ( 0.01 µg/ml ) of K-562 lysate ( 35 µg protein in RIPA buffer ) . Primary incubation was 1 hour. Detected by chemiluminescence. Goat Hu, Ms, Rt E, WB
0.1 mg / €400.00
  Abnova Taiwan Corp.

CRKL pTyr207 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using CrkL (Phospho-Tyr207) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €205.00
  Assay Biotech

CRKL pTyr207 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using CrkL (Phospho-Tyr207) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €310.00
  Assay Biotech

CRKL antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using CrkL (Ab-207) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €205.00
  Assay Biotech

CRKL antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using CrkL (Ab-207) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €310.00
  Assay Biotech

CRKL antibody

Human K562; WB Suggested Anti-CRKL Antibody Titration: 0.2-1 ug/ml. Positive Control: K562 cell lysate. CRKL is strongly supported by BioGPS gene expression data to be expressed in Human K562 cells.; CRKL antibody - middle region (AVARP01043_P050) in Human K562 cells using Western Blot Rabbit Aff - Purified Can, Hu, Ms, Rt P, WB
50 µg / €350.00
  AVIVA Systems Biology

CRKL antibody

CRKL Rabbit IgG Aff - Purified Hu, Ms, Rt WB
0.1 mg / €290.00
  Boster Immunoleader

Items 1 to 20 of 35 total

per page
Page:
  1. 1
  2. 2
  • LinkedIn