CRKL antibody

Principal name

CRKL antibody

Alternative names for CRKL antibody

Crk-like protein, v-crk avian sarcoma virus CT10 oncogene homolog-like

SwissProt ID

P46109 (Human), P47941 (Mouse)

Gene ID

1399 (CRKL), 12929 (Crkl)

Available reactivities

Can (Canine), Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Goat, Mouse

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of CRKL antibody

SH2 and SH3 (Src homology) domains were originally identified as critical functional domains within non-receptor proteins with tyrosine kinase activity. A subset of these proteins appears to exist predominately of SH2/SH3 domains in the absence of detectable catalytic domains. One of the first members of the family to be identified, Crk, is a transformation-specific protein that induces elevation of cellular phosphotyrosine levels, but lacks tyrosine kinase activity itself. A second protein, Nck, consists solely of three SH3 domains and one SH2 domain, while GRB2 contains an SH2 domain flanked on both sides by SH3 domains. A member of this protein class, Crk-L, is encoded by a gene located on chromosome 22, band 11, centromeric of the chronic myelogenous leukemia breakpoint region. Crk-L encodes a 303 amino acid protein with one SH2 and two SH3 domains, and a predicted molecular weight of 36 kDa.

General readings

Zhang,W., et al., (2003) J. Biol. Chem. 278 (26), 23978-23983

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CRKL (C-term) antibody

  Goat Polyclonal Antibody against CRKL  
TA302748 (0.01µg/ml) staining of K562 lysate (35µg protein in RIPA buffer).  Primary incubation was 1 hour.  Detected by chemiluminescence. Goat Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CRKL antibody

  Rabbit Polyclonal anti-CRKL Antibody  
WB Suggested Anti-CRKL Antibody; Titration: 1.0 ug/ml; Positive Control: K562 Whole CellCRKL is strongly supported by BioGPS gene expression data to be expressed in Human K562 cells Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

CRKL antibody

  Rabbit Polyclonal Anti-CRKL Antibody  
WB Suggested Anti-CRKL Antibody Titration: 0.2-1 ug/ml; Positive Control: K562 cell lysate CRKL is strongly supported by BioGPS gene expression data to be expressed in Human K562 cells Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

CRKL antibody

  Rabbit Polyclonal Anti-CRKL Antibody  
Gel: 15%SDS-PAGE, Lysate: 40 ug, Lane 1-3: Lovo cells, Raji cells, A172 cells, Primary antibody: (CRKL Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CRKL antibody

Western blot analysis using CRKL mAb against human CRKL (AA: 100-303) recombinant protein. (Expected MW is 60 kDa) Mouse IgG1 5E12 Ascites Hu E, WB
0.1 ml / €430.00
  Acris Antibodies GmbH

CRKL antibody

Immunohistochemistry analyzes of CrkL antibody (AP20279PU-N) in paraffin-embedded human lung carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CRKL pTyr207 antibody

Immunohistochemistry (IHC) analyzes of p-CrkL (Try207) antibody (Cat.-No.: AP20935PU-N) in paraffin-embedded human lung adenocarcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P
0.1 mg / €350.00
  Acris Antibodies GmbH

CRKL antibody

Immunohistochemistry (IHC) analyzes of CrkL antibody (Cat.-No.: AP21023PU-N) in paraffin-embedded human lung adenocarcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P
0.1 mg / €350.00
  Acris Antibodies GmbH

CRKL antibody

CRKL Goat Purified Hu, Ms WB
0.1 mg / €550.00
  Acris Antibodies GmbH

CRKL pTyr207 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using CrkL (Phospho-Tyr207) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €230.00
  Assay Biotech

CRKL pTyr207 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using CrkL (Phospho-Tyr207) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €330.00
  Assay Biotech

CRKL antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using CrkL (Ab-207) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
50 µg / €230.00
  Assay Biotech

CRKL antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using CrkL (Ab-207) Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, ICC/IF, P, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

Crkl - mouse gene knockout kit via CRISPR

Crkl - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Crkl - mouse gene knockout kit via CRISPR

Crkl - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Crkl - mouse gene knockout kit via CRISPR

Crkl - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Crkl - mouse gene knockout kit via CRISPR

Crkl - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CRKL

  Recombinant protein of human v-crk sarcoma virus CT10 oncogene homolog (avian)-like (CRKL)  
CRKL Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

CRKL (1-303, His-tag)

CRKL Human Purified > 90 % E. coli
0.5 mg / €750.00
  Acris Antibodies GmbH

CRKL (1-303, His-tag)

CRKL Human Purified > 90 % E. coli
0.1 mg / €300.00
  Acris Antibodies GmbH

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