CRLF2 antibody

Principal name

CRLF2 antibody

Alternative names for CRLF2 antibody

Cytokine receptor-like 2, IL-XR, ILXR, TSLPR, Cytokine receptor-like factor 2, Thymic stromal lymphopoietin protein receptor

SwissProt ID

Q8CII9 (Mouse), Q8R4S8 (Rat), Q9HC73 (Human)

Gene ID

64109 (CRLF2), 57914 (Crlf2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of CRLF2 antibody

CRFL2 is a type I membrane receptor that forms a functional heterodimeric complex with IL7R to bind TSLP. The TSLP R contains a WSXWS motif required for proper protein folding and a box1 motif important for association with the JAKs. TSLPR has a predicted molecular weight approximately 41 kD, and two further isoforms have been reported that are produced by alternative splicing. The TSLPR is expressed preferentially in myeloid cells including dendritic cells and activated monocytes, and is weakly expressed in T cells. Expression has also been reported in heart, skeletal muscle, and kidney tissues. TSLP binding to the heterodimeric functional receptor (TSLPR and IL7R) activates JAK2, STAT3 and STAT5 to stimulate cell proliferation. Ligand receptor interactions haves been implicated in the development of the hematopoietic system, dendritic cell maturation, and the maintenance and polarization of human Th2 memory T cells in allergic diseases.

General readings

Blagoev B, Nielsen MM, Angrist M, et al. (2002). Gene 284 (1–2): 161–8.
Reche PA, Soumelis V, Gorman DM, et al. (2001). J. Immunol. 167 (1): 336–43.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CRLF2 antibody

Western blot analysis of TSLP Receptor in human liver tissue lysate with TSLP Receptor antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml. Rabbit IgG Aff - Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CRLF2 antibody

Western blot analysis of TSLP Receptor in mouse heart tissue lysate with TSLP Receptor antibody at 1 µg/ml in (A) the presence and (B) the absence of blocking peptide. Rabbit IgG Aff - Purified Ms E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CRLF2 antibody

WB Suggested Anti-CRLF2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: 721_B cell lysate Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

CRLF2 antibody

Western Blot: CRLF2 Antibody [TA336941] - analysis of TSLPR in an A) partial recombinant protein (0.1 ug/ml), B) human muscle and C) liver lysate (2 ug/ml) using TSLPR antibody. Mouse IgG2a Purified Hu C, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CRLF2 antibody

Western Blot: CRLF2 Antibody [TA336942] - analysis of TSLPR in an A) partial recombinant protein (0.1 ug/ml) and B) human liver lysate (2ug/ml) using TSLPR antibody. Mouse IgG2b Purified Hu C, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CRLF2 antibody

Western Blot: CRLF2 Antibody (59N5G4) [TA337156] - Analysis of CRLF2 in an A) partial recombinant protein (0.1 ug/ml), B) human muscle and C) liver lysate (5 ug/ml) using CRLF2 antibody. Mouse 59N5G4 Purified Hu P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CRLF2 antibody

Western Blot: CRLF2 Antibody [TA337176] - Western blot analysis of CRLF2 antibody in 1. partial recombinant CRLF2 protein 2. Human skeletal muscle lysate and 3. Human liver lysate Rabbit Purified Hu C, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CRLF2 antibody

Thymus stained with TSLP receptor antibody Cat.-No AM10162PU-N in Immunohistochemistry on Paraffin Sections Mouse IgG1 8H8 Purified Hu E, P, WB
0.1 mg / €400.00
  Acris Antibodies GmbH

CRLF2 antibody

The cell lysate of HeLa (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CRLF2 antibody (1:500 ~ 1:5000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG2a AT4E7 Purified Hu E, WB
0.1 ml / €310.00
  Acris Antibodies GmbH

CRLF2 antibody

The cell lysate of HeLa (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CRLF2 antibody (1:500 ~ 1:5000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG2a AT4E7 Purified Hu E, WB
50 µl / €220.00
  Acris Antibodies GmbH

CRLF2 antibody

Formalin fixed, paraffin embedded human liver stained with Rabbit anti Human TSLP receptor (AP05703PU-N) following heat mediated antigen retrieval using sodium citrate buffer (pH6.0) Rabbit IgG Purified Hu P, WB
0.1 mg / €360.00
  Acris Antibodies GmbH

CRLF2 antibody

AP07146PU-N CRLF2 antibody staining of Formalin-Fixed, Paraffin-Embedded Human Kidney at 5 µg/ml followed by biotinylated Goat anti-Rabbit IgG secondary antibody, Alkaline Phosphatase-Streptavidin and Chromogen. Rabbit Purified Hu E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CRLF2 Control Peptide

CRLF2
50 µg / €160.00
  Acris Antibodies GmbH

CRLF2 Control Peptide

CRLF2
50 µg / €160.00
  Acris Antibodies GmbH

CRLF2 antibody

CRLF2 polyclonal antibody (A01), Lot # 051206JC01 Western Blot analysis of CRLF2 expression in Jurkat ( Cat # L017V1 ). Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

CRLF2 antibody

CRLF2 Mouse Hu WB
0.5 mg / €1,400.00
  Abnova Taiwan Corp.

CRLF2 antibody

CRLF2 monoclonal antibody (M03), clone 4A11 Western Blot analysis of CRLF2 expression in Hela NE ( Cat # L013V3 ). Mouse IgG2a 4A11 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CRLF2 antibody

Immunohistochemistry of CRLF2 in human liver tissue with CRLF2 polyclonal antibody ( Cat # PAB13267 ) at 5 µg/ml. Rabbit Hu P, WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

CRLF2 antibody

Western blot analysis of Crlf2 in mouse heart tissue lysate with Crlf2 polyclonal antibody ( Cat # PAB13268 ) at 1 µg/ml in ( A ) the presence and ( B ) the absence of blocking peptide. Rabbit Ms WB
0.1 mg / €390.00
  Abnova Taiwan Corp.

CRLF2 antibody

CRLF2 Rabbit IgG Aff - Purified Hu E, P, WB
50 µg / €480.00
  Novus Biologicals Inc.

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