CRLF2 antibody

Principal name

CRLF2 antibody

Alternative names for CRLF2 antibody

Cytokine receptor-like 2, IL-XR, ILXR, TSLPR, Cytokine receptor-like factor 2, Thymic stromal lymphopoietin protein receptor

SwissProt ID

Q8CII9 (Mouse), Q8R4S8 (Rat), Q9HC73 (Human)

Gene ID

64109 (CRLF2), 57914 (Crlf2)

Available reactivities

Hu (Human), Ms (Mouse)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Flow Cytometry (F)

Background of CRLF2 antibody

TSLP-R, also known as the thymic stromal lymphopoietin protein receptor, cytokine receptor-like 2, CRL2, and IL-XR, is a type I membrane receptor that forms a functional heterodimeric complex with IL-7R to bind with TSLP. The TSLP-R contains a WSXWS motif required for proper protein folding and a box1 motif important for association with the JAKs. TSLP-R has a predicted molecular weight approximately 40 kD, and has two isoforms reported that are produced by alternative splicing. The TSLP-R is expressed preferentially in myeloid cells, dendritic cells, and activated monocytes. It is weakly expressed in T cells. Expression has also been reported in heart, skeletal, muscle, and kidney tissues. TSLP binding to the heterodimeric functional receptor (TSLP-R and IL-7R) activates JAK2, STAT3, and STAT5 to stimulate cell proliferation. Ligand receptor interactions have been implicated in the development of the hematopoietic system, dendritic cell maturation, and the maintenance and polarization of human Th2 memory T cells in allergy diseases.

General readings

Blagoev B, Nielsen MM, Angrist M, et al. (2002). Gene 284 (1–2): 161–8.
Reche PA, Soumelis V, Gorman DM, et al. (2001). J. Immunol. 167 (1): 336–43.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CRLF2 antibody

  Rabbit Polyclonal TSLP Receptor Antibody  
Western blot analysis of TSLP Receptor in human liver tissue lysate with TSLP Receptor antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml. Rabbit IgG Aff - Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CRLF2 antibody

  Rabbit Polyclonal TSLP Receptor Antibody  
Western blot analysis of TSLP Receptor in mouse heart tissue lysate with TSLP Receptor antibody at 1 µg/ml in (A) the presence and (B) the absence of blocking peptide. Rabbit IgG Aff - Purified Ms E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CRLF2 antibody

  Rabbit Polyclonal Anti-CRLF2 Antibody  
WB Suggested Anti-CRLF2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 312500; Positive Control: 721_B cell lysate Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

CRLF2 antibody

  Mouse Polyclonal TSLP R/CRLF2 Antibody  
Western Blot: CRLF2 Antibody [TA336941] - analysis of TSLPR in an A) partial recombinant protein (0.1 ug/ml), B) human muscle and C) liver lysate (2 ug/ml) using TSLPR antibody. Mouse IgG2a Purified Hu C, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CRLF2 antibody

  Mouse Polyclonal TSLP R/CRLF2 Antibody  
Western Blot: CRLF2 Antibody [TA336942] - analysis of TSLPR in an A) partial recombinant protein (0.1 ug/ml) and B) human liver lysate (2ug/ml) using TSLPR antibody. Mouse IgG2b Purified Hu C, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CRLF2 antibody

  Mouse Monoclonal TSLP R/CRLF2 Antibody (59N5G4)  
Western Blot: CRLF2 Antibody (59N5G4) [TA337156] - Analysis of CRLF2 in an A) partial recombinant protein (0.1 ug/ml), B) human muscle and C) liver lysate (5 ug/ml) using CRLF2 antibody. Mouse 59N5G4 Purified Hu P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CRLF2 antibody

  Rabbit Polyclonal TSLP R/CRLF2 Antibody  
Western Blot: CRLF2 Antibody [TA337176] - Western blot analysis of CRLF2 antibody in 1. partial recombinant CRLF2 protein 2. Human skeletal muscle lysate and 3. Human liver lysate Rabbit Purified Hu C, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CRLF2 antibody

  Mouse Monoclonal anti-TSLPR (TSLP-R) Antibody  
Human monocyte-derived dendritic cells stained with purified 1B4, followed by biotinylated anti-mouse IgG and Sav-PE Mouse 1B4 Purified Hu F, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CRLF2 antibody

Thymus stained with TSLP receptor antibody Cat.-No AM10162PU-N in Immunohistochemistry on Paraffin Sections Mouse IgG1 8H8 Purified Hu E, P, WB
0.1 mg / €400.00
  Acris Antibodies GmbH

CRLF2 antibody

The cell lysate of HeLa (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CRLF2 antibody (1:500 ~ 1:5000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG2a AT4E7 Purified Hu E, WB
0.1 ml / €310.00
  Acris Antibodies GmbH

CRLF2 antibody

The cell lysate of HeLa (40ug) were resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human CRLF2 antibody (1:500 ~ 1:5000). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. Mouse IgG2a AT4E7 Purified Hu E, WB
50 µl / €220.00
  Acris Antibodies GmbH

CRLF2 antibody

Formalin fixed, paraffin embedded human liver stained with Rabbit anti Human TSLP receptor (AP05703PU-N) following heat mediated antigen retrieval using sodium citrate buffer (pH6.0) Rabbit IgG Purified Hu P, WB
0.1 mg / €360.00
  Acris Antibodies GmbH

CRLF2 antibody

AP07146PU-N CRLF2 antibody staining of Formalin-Fixed, Paraffin-Embedded Human Kidney at 5 µg/ml followed by biotinylated Goat anti-Rabbit IgG secondary antibody, Alkaline Phosphatase-Streptavidin and Chromogen. Rabbit Purified Hu E, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

CRISPR

Catalog No. Species Donor Vector  

CRLF2 - human gene knockout kit via CRISPR

CRLF2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

CRLF2 - human gene knockout kit via CRISPR

CRLF2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CRLF2 - human gene knockout kit via CRISPR

CRLF2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CRLF2 - human gene knockout kit via CRISPR

CRLF2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Crlf2 - mouse gene knockout kit via CRISPR

Crlf2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Crlf2 - mouse gene knockout kit via CRISPR

Crlf2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CRLF2 (transcript variant 1)

  Recombinant protein of human cytokine receptor-like factor 2 (CRLF2), transcript variant 1  
CRLF2 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

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