CRTAP antibody

Principal name

CRTAP antibody

Alternative names for CRTAP antibody

CASP, Cartilage-associated protein

SwissProt ID

O75718 (Human), Q90830 (Chick), Q9CYD3 (Mouse)

Gene ID

10491 (CRTAP)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of CRTAP antibody

CRTAP is a secreted protein localizing to the extracellular space that plays a role in collagen post-translational modifications, extracellular fibril assembly and intracellular trafficking. CRTAP is widely expressed with predominant expression in articular chondrocytes. It contains a signal peptide and a tetratricopeptide-like helical domain and is essential for normal bone formation. In the endoplasmic reticulum (ER), CRTAP forms a complex with Gros1 and CyPB (cyclophilin B) and is required for the efficient 3-hydroxylation of target prolyl residues in Collagen Type I molecules, the major structural proteins of skin and bone. Mutations in the gene encoding CRTAP can lead to autosomal recessive osteogenesis imperfecta (OI) type 7 and type 2B. OI, also known as brittle bone disease, is characterized by bone fragility and susceptibility to fractures. OI type 7 is a mild form of this disorder, while OI type 2B is a neonatal lethal condition.

General readings

Tonachini L., et al. (1999) Cytogenet Cell Genet. 87: 191-194.
Castagnola P., et al. (1997) J Cell Sci. 110: 1351-1359.

13 Item(s)

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CRTAP antibody

Sample (30 ug of whole cell lysate). A: A431 . 10% SDS PAGE. TA307891 diluted at 1:1000 Rabbit IgG Aff - Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CRTAP antibody

WB Suggested Anti-CRTAP Antibody Titration: 0.2-1 ug/ml; Positive Control: COLO205 cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

CRTAP antibody

CRTAP Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

CRTAP antibody

Immunoperoxidase of monoclonal antibody to CRTAP on formalin-fixed paraffin-embedded human kidney. [antibody concentration 3 ug/ml] Mouse IgG2a 4D9 Purified Hu E, P, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CRTAP antibody

CRTAP Mouse IgG2a 2G5 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CRTAP antibody

Human COLO205; WB Suggested Anti-CRTAP Antibody Titration: 0.2-1 ug/ml. Positive Control: COLO205 cell lysate; CRTAP antibody - N-terminal region (ARP46715_P050) in Human COLO205 cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

CRTAP antibody

Immunofluorescence: CRTAP Antibody [NBP1-32884] - analysis of paraformaldehyde-fixed A431, using Cartilage-associated protein antibody at 1:200 dilution. Rabbit IgG Hu ICC/IF, WB
0.1 ml / €420.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CRTAP

CRTAP Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

CRTAP (His-tag)

CRTAP Human Purified > 85 % by SDS - PAGE E. coli
0.1 mg / €730.00
  Acris Antibodies GmbH

CRTAP (His-tag)

CRTAP Human Purified > 85 % by SDS - PAGE E. coli
20 µg / €300.00
  Acris Antibodies GmbH

CRTAP

CRTAP Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

CRTAP

CRTAP Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates (Overexpressed)

Catalog No.    

CRTAP overexpression lysate

CRTAP overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

13 Item(s)

per page
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