CRTC3 antibody

Principal name

CRTC3 antibody

Alternative names for CRTC3 antibody

TORC3, TORC-3, CREB-regulated transcription coactivator 3, Transducer of regulated cAMP response element-binding protein 3, Transducer of CREB protein 3

SwissProt ID

Q52KS4 (Xenla), Q6UUV7 (Human), Q91X84 (Mouse)

Gene ID

64784 (CRTC3)

Available reactivities

Hu (Human), Mky (Monkey), Ms (Mouse), Rt (Rat)

Available hosts

Rabbit, Mouse

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Enzyme Immunoassay (E), Flow Cytometry (F), Frozen Sections (C)

Background of CRTC3 antibody

Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR) .Tissue specificity: Predominantly expressed in B and T lymphocytes. Highest levels in lung. Also expressed in brain, colon, heart, kidney, ovary, and prostate. Weak expression in liver, pancreas, muscle, small intestine, spleen and stomach.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CRTC3 antibody

Immunohistochemical analysis of paraffin-embedded breast cancer (left) and ovarian cancer (right) using CRTC3 mouse mAb with DAB staining. Mouse IgG1 5G9 Ascites Hu, Mky E, ICC/IF, P, WB
0.1 ml / €430.00
  Acris Antibodies GmbH

CRTC3 antibody

CRTC3 Mouse IgG1 1D9 Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CRTC3 antibody

Western Blot: CRTC3 Antibody [NBP1-46832] - Detection of Human TORC3 by Western Blot and Immunoprecipitation. Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; 50 mcg) cells. Antibodies: Affinity purified rabbit anti- TORC3 antibody A302-703A used for WB at 0.04 mcg/ml (A) and 0.4 mcg/ml (B) and used for IP at 3 mcg/mg lysate. TORC3 was also immunoprecipitated by rabbit anti-TORC3 antibody BL9829, which recognizes an upstream epitope. For blotting immunoprecipitated TORC3, the ReliaBLOT® Reagents and Procedures were used. Detection: Chemiluminescence with exposure times of 10 seconds (A) and 3 seconds (B). Rabbit Aff - Purified Hu IP, WB
0.1 ml / €440.00
  Novus Biologicals Inc.

CRTC3 antibody

Immunohistochemistry-Paraffin: CRTC3 Antibody [NBP1-83615] - Immunohistochemical staining of human liver shows strong cytoplasmic, membranous and nuclear positivity in hepatocytes. Rabbit IgG Aff - Purified Hu ICC/IF, P
0.1 ml / €500.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CRTC3

CRTC3 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

CRTC3

CRTC3 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

6 Item(s)

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