Crumbs homolog 2 antibody

Principal name

Crumbs homolog 2 antibody

Alternative names for Crumbs homolog 2 antibody


SwissProt ID

Q5IJ48 (Human), Q80YA8 (Mouse)

Gene ID

286204 (CRB2)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat)

Available hosts


Available applications

Paraffin Sections (P)

Background of Crumbs homolog 2 antibody

CRB2 Antibody: CRB2 (Crumbs homolog 2), like its homologs CRB1 and CRB3, is similar to the Drosophila crumbs protein and is expressed in reti, brain and kidney. Along with other proteins, the Crumbs proteins form a complex that help set up cell polarity in developing neuroepithelial cells. At the onset of neural specification, embryonic stem cells (ESCs) upregulate CRB2, which then localizes apically in neural rosettes. Gain- and loss-of-function studies of CRB2 have shown that CRB2 is essential for the stabilization of other polarity proteins. Unlike CRB1, mutations in CRB2 do not appear to play a role in retinitis pigmentosa or in Leber congenital amaurosis.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Crumbs homolog 2 antibody

Western blot analysis of CRB2 in rat brain tissue lysate with CRB2 antibody at (A) 1 and (B) 2 ug/mL Rabbit IgG Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

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