CTBP1 antibody
Principal name
CTBP1 antibody
Alternative names for CTBP1 antibody
C-terminal-binding protein 1, CTBP
Ncbi ID
NP_001319, 9606, NP_001012632, NP_001012632.1, AAH53320, NM_001012614, NP_001185788.1, NM_013502, NM_019201
Available reactivities
Available hosts
Available applications
Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Flow Cytometry (F), ELISA (detection) (E(detection))
Background of CTBP1 antibody
CTBP1, C-terminal-binding protein 1, is a protein that in humans is encoded by the CTBP1 gene. The CtBP1 protein binds to the C-terminus of adenovirus E1A proteins. This gene is mapped to 4p16.This phosphoprotein is a transcriptional repressor (corepressor) and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. CtBP1 and CtBP2 preferentially associate with the E1A via a 5 amino acid motif, PLDLS, to repress E1A induced oncogenesis and cellular transformation. CtBP1 is expressed from embryo to adult, but CtBP2 is mainly expressed during embryogenesis. During skeletal and T cell development, CtBP1 and CtBP2 associate with the PLDLSL domain of δEF1, a cellular zinc finger-homeodomain protein, and thereby enhances δEF1-induced transcriptional silencing. In addition, CtBP complexes with CtIP, a 125 kDa protein that recognizes distinctly different protein motifs from CtBP. CtIP binds to the BRCT repeats within the breast cancer gene BRCA1 and enables CtBP to influence BRCA1 activity. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.
General readings
1. Lopez-Garcia J, Periyasamy M, Thomas RS, Christian M, Leao M, Jat P, Kindle KB, Heery DM, Parker MG, Buluwela L, Kamalati T, Ali S.: ZNF366 is an estrogen receptor corepressor that acts through CtBP and histone deacetylases. Nucleic Acids Res. 2006; 34(21):6126-36.
2. Nadauld LD, Phelps R, Moore BC, Eisinger A, Sandoval IT, Chidester S, Peterson PW, Manos EJ, Sklow B, Burt RW, Jones D.A.: Adenomatous polyposis coli control of C-terminal
binding protein-1 stability regulates expression of intestinal retinol dehydrogenases. J Biol Chem. 2006 Dec 8;281(49):37828-35.
3. Valenta T, Lukas J, Korinek V.: HMG box transcription factor TCF-4's interaction with CtBP1 controls the expression of the Wnt target Axin2/Conductin in human embryonic kidney cells. Nucleic Acids Res. 2003 May 1;31(9):2369-80.
4. Valenta T, Lukas J, Doubravska L, Fafilek B, Korinek V.: HIC1 attenuates Wnt signaling by recruitment of TCF-4 and beta-catenin to the nuclear bodies. EMBO J. 2006 Jun
7;25(11):2326-37.

























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Primary Antibodies
Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
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TA308690 | CTBP1 antibody |
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Rabbit polyclonal antibody to CtBP1 (C-terminal binding protein 1) | |||||||
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Rabbit | IgG | Aff - Purified | Hu | ICC/IF, WB |
0.1 ml /
€416.00
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OriGene Technologies, Inc. | |||||||
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TA313245 | CTBP1 antibody |
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Rabbit polyclonal CtBP1 (Ab-422) antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms | E, P, WB |
0.1 ml /
€335.00
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OriGene Technologies, Inc. | |||||||
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TA313246 | CTBP1 antibody |
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Rabbit polyclonal CtBP1 (Ser422) antibody(Phospho-specific) | |||||||
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Rabbit | IgG | Purified | Hu, Ms | E, P, WB |
0.1 ml /
€335.00
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OriGene Technologies, Inc. | |||||||
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TA324588 | CTBP1 (C-term) antibody |
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Rabbit polyclonal CTBP1 Antibody (C-term) | |||||||
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Rabbit | Ig | Aff - Purified | Hu | WB |
0.4 ml /
€410.00
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OriGene Technologies, Inc. | |||||||
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TA327149 | CTBP1 antibody |
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Rabbit anti-CTBP1 Polyclonal Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt |
0.1 mg /
€335.00
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OriGene Technologies, Inc. | |||||||
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TA330555 | CTBP1 antibody |
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Rabbit Polyclonal Anti-CTBP1 Antibody | |||||||
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Rabbit | IgG | Purified | Can, Eq, Hu, Ms, Por, Rt | P, WB |
50 µg /
€360.00
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OriGene Technologies, Inc. | |||||||
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TA330556 | CTBP1 antibody |
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Rabbit Polyclonal Anti-CTBP1 Antibody | |||||||
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Rabbit | IgG | Purified | Can, Eq, Hu, Ms, Por, Rt | WB |
0.1 mg /
€360.00
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OriGene Technologies, Inc. | |||||||
TA330557 | CTBP1 antibody |
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Rabbit Polyclonal Anti-CTBP1 Antibody | |||||||
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Rabbit | IgG | Purified | Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Ze | WB |
50 µg /
€360.00
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OriGene Technologies, Inc. | |||||||
TA347791 | CTBP1 antibody |
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Rabbit Polyclonal Anti-CtBP1 Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | WB |
0.1 mg /
€335.00
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OriGene Technologies, Inc. | |||||||
TA348444 | CTBP1 antibody |
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Rabbit Polyclonal Anti-Phospho-CtBP1(Ser422) Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | WB |
0.1 mg /
€335.00
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OriGene Technologies, Inc. | |||||||
TA351112 | CTBP1 antibody |
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Rabbit Polyclonal Anti-CTBP1 Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | E, P, WB |
0.1 ml /
€335.00
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OriGene Technologies, Inc. | |||||||
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TA352016 | CTBP1 antibody |
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Rabbit Polyclonal Anti-CTBP1 Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms, Rt | E, P |
0.1 ml /
€335.00
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OriGene Technologies, Inc. | |||||||
AM09387PU-N | CTBP1 antibody |
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Mouse | IgG2b | AT4D6 | Purified | Hu | E, F, ICC/IF, WB |
0.1 ml /
€310.00
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Acris Antibodies GmbH | |||||||
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AM09387PU-S | CTBP1 antibody |
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Mouse | IgG2b | AT4D6 | Purified | Hu | E, F, ICC/IF, WB |
50 µl /
€230.00
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Acris Antibodies GmbH | |||||||
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AP03000PU-N | CTBP1 antibody |
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Rabbit | Aff - Purified | Hu, Ms | ICC/IF, IP, WB |
0.1 mg /
€260.00
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Acris Antibodies GmbH | |||||||
AP32227PU-N | CTBP1 antibody |
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Rabbit | IgG | Aff - Purified | Hu, Ms, Rt | E, P, WB |
50 µl /
€380.00
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Acris Antibodies GmbH | |||||||
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AP51115PU-N | CTBP1 (C-term) antibody |
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Rabbit | Ig | Aff - Purified | Hu, Ms | WB |
0.4 ml /
€370.00
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Acris Antibodies GmbH | |||||||
AP55814PU-N | CTBP1 pSer422 antibody |
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Rabbit | Aff - Purified | Hu, Ms, Rt | P, WB |
0.1 mg /
€340.00
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Acris Antibodies GmbH | |||||||
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AP55814PU-S | CTBP1 pSer422 antibody |
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Rabbit | Aff - Purified | Hu, Ms, Rt | P, WB |
50 µg /
€270.00
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Acris Antibodies GmbH | |||||||
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A8325-1 | CTBP1 pSer422 antibody |
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Rabbit | Aff - Purified | Hu, Ms, Rt | E, P, WB |
50 µg /
€230.00
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Assay Biotech | |||||||
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