CTBP2 antibody

Principal name

CTBP2 antibody

Alternative names for CTBP2 antibody

C-terminal-binding protein 2

SwissProt ID

P56545 (Human), P56546 (Mouse), Q0VCQ1 (Bovin), Q9DEG6, Q9EQH5 (Rat), Q9W758 (Xenla)

Gene ID

1488 (CTBP2), 65230 (ctbp2)

Available reactivities

Hu (Human), Ge (Gerbil), Ms (Mouse), Rt (Rat), Ze (Zebrafish), Bov (Bovine), Can (Canine), Chk (Chicken), Eq (Equine), GP (Guinea Pig), Gt (Goat), Por (Porcine), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), ELISA (detection) (E(detection)), Paraffin Sections (P), Frozen Sections (C)

Background of CTBP2 antibody

CtBP1 is a 48 kDa cellular phosphoprotein that associates with various proteins and functions as a corepressor of transcription. CtBP1 and the related protein CtBP2 are characterized as C-terminal binding proteins of adenovirus E1A, and they preferentially associate with the E1A via a 5 amino acid motif, PLDLS, to repress E1A induced oncogenesis and cellular transformation.CtBP1 is expressed from embryo to adult, but CtBP2 is mainly expressed during embryogenesis. During skeletal and T cell development, CtBP1 and CtBP2 associate with the PLDLSL domain of deltaEF1, a cellular zinc finger-homeodomainprotein, and thereby enhances deltaEF1-induced transcriptional silencing. In addition, CtBP complexes with CtIP, a 125 kDa protein that recognizes distinctly different protein motifs from CtBP. CtIP binds to the BRCT repeats within the breast cancer gene BRCA1 and enables CtBP to influence BRCA1 activity. CtIP/CtBP binding to BRCA1 inhibits the transactivation of the p21 promoter, and it is critical for regulating p21 transcription in response to DNA damage.

General readings

Dammer,E.B. (2008) J. Biol. Chem. 283 (11), 6925-6934

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CTBP2 antibody

Host: Rabbit; Target Name: CTBP2; Sample Tissue: Human Adult Placenta; Antibody Dilution: 1.0 ug/ml Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Por, Rb, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

CTBP2 antibody

Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-CTBP2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1mM EDTA in 10mM Tris buffer (pH8.5) at 120°C for 3 min, TA807909)(1:150) Mouse IgG1 OTI4D4 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CTBP2 antibody

Mouse retina; . Sample Type: complete mouse retina sections. Red: Primary. Blue: DAPI. Primary Dilution: 1:200. Secondary Antibody: Goat anti-Rabbit AF568 IgG(H+L). Secondary Dilution: 1:200. Image Submitted by: David Zenisek. Yale University .; CTBP2 antibody - C-terminal region (ARP50670_P050) in Mouse retina cells using Immunohistochemistry Rabbit Aff - Purified Bov, Can, Chk, Hu, Ms, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

CTBP2 antibody

CtBP2 antibody detects CTBP2 protein by Western blot analysis. A. 30 ug A375 whole cell lysate/extract. 7.5 % SDS-PAGE. CtBP2 antibody (TA307965) dilution: 1:500 Rabbit IgG Aff - Purified Hu ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CTBP2 antibody

Western blot analysis of extracts from HeLa cells and 293 cells, using CtBP2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CTBP2 antibody

Predicted cell location: Nucleus. Positive control: Human gastric and ovarian cancer tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded human gastric cancer tissue using CTBP2 antibody at dilution 1/25, on the right is treated with the fusion protein. (Original magnification:x 200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

CTBP2 antibody

Predicted band size: 106 kDa . Positive control: PC3 cell lysate. Recommended dilution: 1/500-2000. (Gel: 8%SDS-PAGE Lysate: 40 ug per lane Primary antibody: 1/300 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 2 minutes) Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CTBP2 antibody

WB Suggested Anti-CTBP2 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: A549 cell lysateCTBP2 is strongly supported by BioGPS gene expression data to be expressed in Human A549 cells Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Por, Rb, Rt P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

CTBP2 antibody

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CTBP2 (RC213283, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CTBP2.(1:500) Mouse IgG1 OTI3G4 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CTBP2 antibody

Immunohistochemistry analyzes of CtBP2 antibody (Cat.-No.: AP20425PU-N) in paraffin-embedded human breast carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CTBP2 (N-term) antibody

Formalin fixed, paraffin embedded human rectum tissue stained with CTBP2 Antibody (N-term) Cat.-No AP51117PU-N followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of CTBP2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. Rabbit Ig Aff - Purified Hu P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CTBP2 antibody

CTBP2 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

CTBP2 antibody

CTBP2 Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

CTBP2 antibody

CTBP2 MaxPab polyclonal antibody. Western Blot analysis of CTBP2 expression in human pancreas. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

CTBP2 antibody

CTBP2 Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

CTBP2 antibody

Western blot analysis of extracts from HeLa/293 cells, using CtBP2 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €205.00
  Assay Biotech

CTBP2 antibody

Western blot analysis of extracts from HeLa/293 cells, using CtBP2 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €310.00
  Assay Biotech

CTBP2 antibody

CTBP2 Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

CTBP2 antibody

CTBP2 Rabbit IgG Aff - Purified Hu, Ms, Rt C, ICC/IF, P, WB
0.1 mg / €290.00
  Boster Immunoleader

CTBP2 antibody

Immunohistochemical analysis of CTBP2 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Hu, Ms, Rt ICC/IF, P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

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