CTDSP1 antibody

Principal name

CTDSP1 antibody

Alternative names for CTDSP1 antibody

NIF3, NLIIF, SCP1, NLI-interacting factor 3, NLI-IF, Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, Small C-terminal domain phosphatase 1

SwissProt ID

P58466 (Mouse), Q9GZU7 (Human)

Gene ID

58190 (CTDSP1), 227292 (Ctdsp1)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Mky (Monkey)

Available hosts

Rabbit, Goat, Mouse

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), Immunoprecipitation (IP), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F)

Background of CTDSP1 antibody

CTDSP1 is a class 2C phosphatase with activity dependent on the conserved DxD motif. Expression of CTDSP1 inhibited activated transcription from several promoter-reporter gene constructs, but expression of a mutant lacking phosphatase activity enhanced transcription. Neuronal gene transcription is repressed in nonneuronal cells by the repressor element-1 (RE1)-silencing transcription factor/neuron-restrictive silencer factor (REST/NRSF; 600571) complex. REST/NRSF recruits SCPs to neuronal genes that contain RE1 elements, leading to neuronal gene silencing in nonneuronal cells. Phosphatase-inactive forms of SCP interfere with REST/NRSF function and promote neuronal differentiation of P19 stem cells. Likewise, small interfering RNA directed to the single Drosophila SCP unmasks neuronal gene expression in S2 cells. Thus, SCP activity is an evolutionarily conserved transcriptional regulator that acts globally to silence neuronal genes.

General readings

Maiello B., et al. (2001) Front Biosci. 6: 1358-1368.
Palancade B., et al. (2004) J Mol Biol. 335:415-424.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CTDSP1 antibody

  CTDSP1 mouse monoclonal antibody, clone OTI1B6 (formerly 1B6)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-CTDSP1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502225) Mouse IgG1 OTI1B6 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CTDSP1 antibody

  CTDSP1 mouse monoclonal antibody, clone OTI1G1 (formerly 1G1)  
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-CTDSP1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502270) Mouse IgG1 OTI1G1 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CTDSP1 antibody

Staining of Mouse Testis lysate (35µg protein in RIPA buffer) using CTDSP1 Antibody Cat.-No AP31837PU-N at 0.1 µg/ml. Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt E, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CTDSP1 (C-term) antibody

  Rabbit Polyclonal Antibody against CTDSP1 (C-term)  
The anti-CTDSP1-V250 (Cat. #TA302078) is used in Western blot to detect CTDSP1-V250 in CEM tissue lysate. Rabbit Ig Purified Hu P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CTDSP1 antibody

  Rabbit polyclonal CTDSP1 antibody  
Western blot analysis of extracts from HUVEC cells and HeLa cells, using CTDSP1 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CTDSP1 antibody

  CTDSP1 mouse monoclonal antibody, clone OTI1B5 (formerly 1B5)  
Immunohistochemical staining of paraffin-embedded Human lymph node tissue within the normal limits using anti-CTDSP1 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA502208) Mouse IgG1 OTI1B5 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CTDSP1 antibody

  CTDSP1 mouse monoclonal antibody, clone OTI1A7 (formerly 1A7)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CTDSP1 (RC212037, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CTDSP1. Mouse IgG1 OTI1A7 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CTDSP1 antibody

  CTDSP1 mouse monoclonal antibody, clone OTI1D3 (formerly 1D3)  
Anti-CTDSP1 mouse monoclonal antibody (TA502226) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CTDSP1(RC212037). Mouse IgG1 OTI1D3 Purified Can, Hu, Mky, Rt ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CTDSP1 antibody

  CTDSP1 mouse monoclonal antibody, clone OTI1G2 (formerly 1G2)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CTDSP1 (RC212037, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CTDSP1. Mouse IgG1 OTI1G2 Purified Hu F, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CTDSP1 antibody

  CTDSP1 mouse monoclonal antibody, clone OTI1A10 (formerly 1A10)  
Anti-CTDSP1 mouse monoclonal antibody (TA502246) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY CTDSP1(RC212037). Mouse IgG1 OTI1A10 Purified Hu F, ICC/IF, WB
0.1 ml / €379.00
  OriGene Technologies, Inc.

TrueMAB

CTDSP1 antibody

  CTDSP1 mouse monoclonal antibody, clone OTI1C3 (formerly 1C3)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CTDSP1 (RC212037, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CTDSP1. Mouse IgG2b OTI1C3 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CTDSP1 antibody

  CTDSP1 mouse monoclonal antibody, clone OTI1F4 (formerly 1F4)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY CTDSP1 (RC212037, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-CTDSP1. Mouse IgG2b OTI1F4 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

CTDSP1 (N-term) antibody

Western blot analysis of CTDSP1 Antibody (N-term) Cat.-No AP51118PU-N in Jurkat cell line lysates (35ug/lane). This demonstrates the CTDSP1 antibody detected the CTDSP1 protein (arrow). Rabbit Ig Aff - Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CTDSP1 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using CTDSP1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €230.00
  Assay Biotech

CTDSP1 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using CTDSP1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

CTDSP1 - human gene knockout kit via CRISPR

CTDSP1 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

CTDSP1 - human gene knockout kit via CRISPR

CTDSP1 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CTDSP1 - human gene knockout kit via CRISPR

CTDSP1 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CTDSP1 - human gene knockout kit via CRISPR

CTDSP1 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CTDSP1 (transcript variant 2)

  Recombinant protein of human CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 (CTDSP1), transcript variant 2  
CTDSP1 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

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