Cullin-2 antibody

Principal name

Cullin-2 antibody

Alternative names for Cullin-2 antibody

CUL-2, CUL2

SwissProt ID

Q13617 (Human), Q9D4H8 (Mouse)

Gene ID

8453 (CUL2), 71745 (Cul2)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Rt (Rat), African clawed frog, Chk (Chicken), Por (Porcine)

Available hosts

Mouse, Rabbit, Goat

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Immunoprecipitation (IP)

Background of Cullin-2 antibody

Cullin proteins comprise a distinct family of mediators that participate in the selective targeting of proteins for ubiquitin (Ub)-mediated proteolysis. CUL-1, which is the mammalian homolog of Cdc53 from yeast, is an integral component of the E3 ubiquitin ligase complex designated SCF. The SCF(Skp1/CUL-1/F-box protein complex) consists of Skp1 associating with both CUL-1 and an F-box protein, such as Skp2, which determines the substrate specificity of the complex. CUL-1 mediated ubiquitination results in the degradation of cell cycle proteins cyclin D, p21 and cyclin E. Another cullin, CUL-3 facilitates the degradation of cyclin E independent of SCF activity, while CUL-2 associates with the tumor suppressing protein VHL and elongin B to form VBC complexes, which structurally resemble the SCF ligase. Proteolysis also occurs by way of CUL-4 associating with Nedd-8, a ubiquitin- like protein, where it too functions as an active component of a multifunctional E3 complex. CUL-5, or vasopressin-activated, calcium-mobilizing protein (VACM-1), is also included in the cullin family as it shares substantial sequence homology with CUL-1.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Cullin-2 antibody

  Rabbit polyclonal anti-Cullin 2 antibody  
Western blot analysis of extracts from LOVO cells, using Cullin 2 antibody (#TA314751).The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms E, ICC/IF, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cullin-2 (C-term) antibody

  Goat Anti-CUL2 Antibody  
(1ug/ml) staining of NIH3T3 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cullin-2 (C-term) antibody

  Rabbit polyclonal anti-Cul2 antibody  
Anti-CUL2 antibody was diluted 1:500 to detect CUL2 in human prostate tissue. Tissue was formalin fixed and paraffin embedded. No pre-treatment of sample was required. The image shows the localization of antibody as the precipitated red signal, with a hematoxylin purple nuclear counter stain. Rabbit Serum Hu E, IP, WB
0.1 ml / €356.00
  OriGene Technologies, Inc.

Cullin-2 antibody

  Anti-CUL2 Rabbit Polyclonal Antibody  
Western blot analysis of PC3 cell using TA322839(CUL2 Antibody) at dilution 1/440 Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cullin-2 antibody

  Rabbit Polyclonal Anti-CUL2 Antibody  
Cullin-2 Rabbit IgG Purified Hu WB
50 µg / €325.00
  OriGene Technologies, Inc.

Cullin-2 antibody

  Rabbit anti-CUL2 Polyclonal Antibody  
Western blot analysis of extracts of various cell lines, using CUL2 antibody. Rabbit IgG Purified Hu, Ms, Rt
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cullin-2 antibody

  Rabbit Polyclonal Anti-Cullin 2 Antibody  
Western blot analysis on LOVO cell lysate using Cullin 2 Antibody Rabbit IgG Purified Hu, Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cullin-2 antibody

  Rabbit Polyclonal anti-Cullin-2 (CUL-2) Antibody  
Human Tonsil stained with anti-Cullin-2 (CUL-2) antibody. Rabbit IgG Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cullin-2 antibody

Immunohistochemical (IHC) analysis in paraffin-embedded human lung carcinoma tissue using Cullin-2 antibody (Cat-No. AP06078PU-N). Rabbit Aff - Purified Hu, Ms ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Cullin-2 antibody

Prostate: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Hu E, IP, P, WB
50 µl / €470.00
  Acris Antibodies GmbH

Cullin-2 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Cullin 2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, P, WB
50 µg / €230.00
  Assay Biotech

Cullin-2 antibody

Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue, using Cullin 2 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms E, ICC/IF, P, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

CUL2 - human gene knockout kit via CRISPR

CUL2 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

CUL2 - human gene knockout kit via CRISPR

CUL2 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CUL2 - human gene knockout kit via CRISPR

CUL2 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CUL2 - human gene knockout kit via CRISPR

CUL2 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cul2 - mouse gene knockout kit via CRISPR

Cul2 - mouse gene knockout kit via CRISPR Mouse GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

Cul2 - mouse gene knockout kit via CRISPR

Cul2 - mouse gene knockout kit via CRISPR Mouse mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cul2 - mouse gene knockout kit via CRISPR

Cul2 - mouse gene knockout kit via CRISPR Mouse Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

Cul2 - mouse gene knockout kit via CRISPR

Cul2 - mouse gene knockout kit via CRISPR Mouse RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

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