Cullin-4A antibody

Principal name

Cullin-4A antibody

Alternative names for Cullin-4A antibody

CUL-4A, CUL4A

SwissProt ID

Q13619 (Human), Q3TCH7 (Mouse)

Gene ID

8451 (CUL4A)

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Mky (Monkey)

Available hosts

Rabbit, Mouse

Available applications

Enzyme Immunoassay (E), Immunoprecipitation (IP), Western blot / Immunoblot (WB), Paraffin Sections (P), PLA/Proximity ligation assay (PLA), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Frozen Sections (C)

Background of Cullin-4A antibody

CUL4a is a core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The E3 ubiquitin-protein ligase activity of the complex is dependent on the neddylation of the cullin subunit and is inhibited by the association of the deneddylated cullin subunit with TIP120A/CAND1. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. DCX(DET1-COP1) directs ubiquitination of JUN. DCX(DDB2) directs ubiquitination of XPC. In association with RBX1, DDB1 and DDB2 is required for histone H3 and histone H4 ubiquitination in response to ultraviolet and may be important for subsequent DNA repair. DCX(DTL) plays a role in PCNA-dependent polyubiquitination of CDT1 and MDM2-dependent ubiquitiantion of TP53 in response to radiation-induced DNA damage and during DNA replication. In association with DDB1 and SKP2 probably is involved in ubiquitination of CDKN1B/p27kip. Is involved in ubiquitination of HOXA9.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Cullin-4A antibody

CUL4A MaxPab rabbit polyclonal antibody. Western Blot analysis of CUL4A expression in mouse lung. Rabbit Purified Hu, Ms E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

Cullin-4A (N-term) antibody

Western blot analysis of CUL4a (arrow) using rabbit polyclonal CUL4a Antibody (Human N-term) (Cat.#TA302188).293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the CUL4a gene (Lane 2) (Origene Technologies). Rabbit Ig Purified Hu WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cullin-4A (N-term) antibody

Immunohistochemistry. anti-CUL4 antibody was diluted 1:500 to detect CUL4 in human testes tissue. Tissue was formalin fixed and paraffin embedded. No pre-treatment of sample was required. The image shows the localization of antibody as the precipitated red signal, with a hematoxylin purple nuclear counter stain. Rabbit Serum Hu, Ms E, IP, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cullin-4A antibody

Western blot analysis of Human fetal muscle and fetal brain tissue, hela cell using TA321259(CUL4A Antibody) at dilution 1/325 Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cullin-4A antibody

Western blot analysis of Human fetal muscle and brain tissue using TA321260(CUL4A Antibody) at dilution 1/450 Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cullin-4A antibody

Testis: Formalin-Fixed Paraffin-Embedded (FFPE) Rabbit Hu, Ms E, IP, P, WB
50 µl / €470.00
  Acris Antibodies GmbH

Cullin-4A antibody

Western Blot analysis of CUL4A expression in transfected 293T cell line by CUL4A polyclonal antibody (A01).

Lane1:CUL4A transfected lysate(87.68 KDa).
Lane2:Non-transfected lysate. Mouse Serum Hu E, WB
50 µl / €290.00
  Abnova Taiwan Corp.

Cullin-4A antibody

Cullin-4A Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

Cullin-4A antibody

Cullin-4A Mouse IgG2b 3H3 Purified Hu E
0.1 mg / €370.00
  Abnova Taiwan Corp.

Cullin-4A antibody

Western blot analysis of CUL4A ( arrow ) using rabbit CUL4A polyclonal antibody ( Cat # PAB2988 ) . 293 cell lysates ( 2 µg/lane ) either nontransfected ( Lane 1 ) or transiently transfected with the CUL4A gene ( Lane 2 ) ( Origene Technologies ) . Rabbit Hu E, WB
0.4 ml / €390.00
  Abnova Taiwan Corp.

Cullin-4A antibody

Immunohistochemical staining with CUL4A polyclonal antibody ( Cat # PAB10038 ) was diluted 1 : 500 to detect CUL4 in human testis tissue. Tissue was formalin fixed and paraffin embedded. No pre-treatment of sample was required. The image shows the localization of antibody as the precipitated red signal, with a hematoxylin purple nuclear counter stain. Hu, Ms
0.1 ml / €560.00
  Abnova Taiwan Corp.

Cullin-4A (Center) antibody

Human Fetal heart; WB Suggested Anti-CUL4A Antibody. . Titration: 1.0 ug/ml. . Positive Control: Fetal Heart; CUL4A antibody - middle region (ARP61665_P050) in Human Fetal heart cells using Western Blot Rabbit Aff - Purified Hu WB
50 µg / €350.00
  AVIVA Systems Biology

Cullin-4A antibody

Western Blot: Cul4a Antibody [NB100-2266] - Detection of Human Cul4a by Western Blot of  Immunoprecipitates. Samples: Whole cell lysate (1 mg for IP,  20% of IP loaded) from HeLa cells.  Antibodies: Affinity purified  rabbit anti-Cul4a antibody NB100-2266 used  for IP at 3 mcg/mg lysate (B). Cul4a was also  immunoprecipitated by rabbit anti-Cul4a antibody NB100-2267.  Detection: Chemiluminescence with an exposure time of 3  minutes. Rabbit Aff - Purified Hu IP
0.1 mg / €440.00
  Novus Biologicals Inc.

Cullin-4A antibody

Immunohistochemistry-Paraffin: Cullin 4a Antibody [NB100-2267] - FFPE section of human breast tumor.   Affinity purified rabbit anti-Cul4a used at a dilution of 1:500.  Detection: DAB staining using Immunohistochemistry Accessory Kit. Rabbit Aff - Purified Hu, Ms IP, P, PLA, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Cullin-4A antibody

Immunohistochemistry-Paraffin: Cullin 4a Antibody [NBP1-78040] anti-CUL4 antibody was diluted 1:500 to detect CUL4 in human testes tissue. Tissue was formalin fixed and paraffin embedded. No pre-treatment of sample was required. Rabbit Purified Hu C, E, IP, P, WB
0.1 ml / €510.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Cullin-4A (transcript variant 2)

Cullin-4A Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Cullin-4A

Cullin-4A Human Purified
2 µg / €300.00
  Abnova Taiwan Corp.

Cullin-4A

Cullin-4A Human
10 µg / €380.00
  Abnova Taiwan Corp.

Cullin-4A

Cullin-4A Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

Cullin-4A

Cullin-4A Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
25 µg / €510.00
  Abnova Taiwan Corp.

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