Cullin-4B antibody
Principal name
Cullin-4B antibody
Alternative names for Cullin-4B antibody
CUL-4B, CUL4B, KIAA0695
SwissProt ID
Q13620 (Human)
Gene ID
8450 (CUL4B)
Ncbi ID
Available reactivities
Available hosts
Available applications
ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), Paraffin Sections (P), Enzyme Immunoassay (E)
Background of Cullin-4B antibody
Cullin 4B/CUL4B encodes a scaffold protein that organizes a cullin-RING (really interesting new gene) ubiquitin ligase (E3) complex in ubiquitylation. The CUL4 gene encodes a protein of 913 amino acids. The cullin domain is located between amino acid residues 217 and 815 and is characterized a by C-terminal globular domain (cullin homology domain) and a series of N-terminal repeats (cullin repeats). Ohtake et al. (2007) characterize a fat-soluble ligand-dependent ubiquitin ligase complex in human cell lines, in which dioxin receptor (AhR) is integrated as a component of a novel cullin 4B ubiquitin ligase complex, CUL4B(AhR). Complex assembly and ubiquitin ligase activity of CUL4B(AhR) in vitro and in vivo are dependent on the AhR ligand. In the CUL4B(AhR) complex, ligand-activated AhR acts as a substrate-specific adaptor component that targets sex steroid receptors for degradation. Their findings uncover a function for AhR as an atypical component of the ubiquitin ligase complex and demonstrate a non-genomic signalling pathway in which fat-soluble ligands regulate target-protein-selective degradation through a ubiquitin ligase complex.































- Quick-Filters:
- Highly Validated (2)
Primary Antibodies
Catalog No. | Host | Iso. | Clone | Pres. | React. | Applications | |
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TA590752 | Cullin-4B antibody |
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Rabbit Polyclonal CUL4B Antibody | |||||||
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Rabbit | IgG | Purified | Hu | E, ICC/IF, P, WB |
50 µg /
€409.00
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OriGene Technologies, Inc. | |||||||
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Highly validated antibody! |
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TA800444 | Cullin-4B antibody |
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CUL4B mouse monoclonal antibody, clone OTI1C4 (formerly 1C4) | |||||||
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Mouse | IgG2b | OTI1C4 | Purified | Can, Hu, Ms | P, WB |
0.1 ml /
€379.00
|
OriGene Technologies, Inc. | |||||||
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Highly validated antibody! |
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TA324698 | Cullin-4B antibody |
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Rabbit polyclonal CUL4B Antibody (Center) | |||||||
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Rabbit | IgG | Purified | Hu, Ms | WB |
0.4 ml /
€410.00
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OriGene Technologies, Inc. | |||||||
TA351114 | Cullin-4B antibody |
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Rabbit Polyclonal Anti-CUL4B Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms | E, WB |
0.1 ml /
€335.00
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OriGene Technologies, Inc. | |||||||
TA351115 | Cullin-4B antibody |
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Rabbit Polyclonal Anti-CUL4B Antibody | |||||||
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Rabbit | IgG | Purified | Hu, Ms | E, P |
0.1 ml /
€335.00
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|
OriGene Technologies, Inc. | |||||||
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TA800391 | Cullin-4B antibody |
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CUL4B mouse monoclonal antibody, clone OTI7G10 (formerly 7G10) | |||||||
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Mouse | IgG1 | OTI7G10 | Purified | Hu | WB |
0.1 ml /
€350.00
|
OriGene Technologies, Inc. | |||||||
TA800411 | Cullin-4B antibody |
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CUL4B mouse monoclonal antibody, clone OTI7F8 (formerly 7F8) | |||||||
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Mouse | IgG1 | OTI7F8 | Purified | Can, Hu, Mky, Ms, Rt | WB |
0.1 ml /
€350.00
|
OriGene Technologies, Inc. | |||||||
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AP23317PU-N | Cullin-4B antibody |
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Rabbit | IgG | Aff - Purified | Hu, Rt, Ze | P, WB |
0.1 mg /
€390.00
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Acris Antibodies GmbH | |||||||
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CRISPR
Catalog No. | Species | Donor Vector | |
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KN206935 | CUL4B - human gene knockout kit via CRISPR |
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Human | GFP-Puro |
1 kit /
€1,290.00
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OriGene Technologies, Inc. | |||
KN206935BN | CUL4B - human gene knockout kit via CRISPR |
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Human | mBFP-Neo |
1 kit /
€1,290.00
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OriGene Technologies, Inc. | |||
KN206935LP | CUL4B - human gene knockout kit via CRISPR |
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Human | Luciferase-Puro |
1 kit /
€1,290.00
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OriGene Technologies, Inc. | |||
KN206935RB | CUL4B - human gene knockout kit via CRISPR |
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Human | RFP-BSD |
1 kit /
€1,290.00
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OriGene Technologies, Inc. |
Proteins & Growth Factors
Catalog No. | Species | Pres. | Purity | Source | |
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TP306935 | Cullin-4B (transcript variant 1) |
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Recombinant protein of human cullin 4B (CUL4B), transcript variant 1 | |||||
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Human | > 80 % Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps. Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining. |
HEK293 cells |
20 µg /
€438.00
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OriGene Technologies, Inc. | |||||