Cyclin G1 antibody

Principal name

Cyclin G1 antibody

Alternative names for Cyclin G1 antibody

Cyclin-G1, Cyclin-G, CCNG1, CCNG, CYCG1

SwissProt ID

P39950 (Rat), P51945 (Mouse), P51959 (Human), Q52QT8 (Pig), Q5E9I1 (Bovin)

Gene ID

900 (CCNG1), 12450 (Ccng1), 25405

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Por (Porcine)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F)

Background of Cyclin G1 antibody

Cyclins are the regulatory subunits of Cdc2 p34 and related cyclin-dependent kinases (Cdks) which play critical roles in the control of cell cycle progression. The catalytic subunit for cyclin A and B is Cdc2 p34 kinase. The Cdc2- cyclin B complex controls the G2 to M transition whereas Cdc2-cyclin A regulates S phase progression. The G1 to S transition, however, appears to be controlled by the G1 cyclins. Cyclin D1 accumulates during G1 and associates with Cdk2, Cdk4 and Cdk5. Cyclin E and Cdk2 interact during the G1 to S transition. Cyclin G contains a typical N terminal cyclin box and a carboxy terminal domain sequence homologous to the tyrosine phosphorylation site of the epidermal growth factor receptor. Cyclin G expression is induced within 3 hours after growth stimulation and remains elevated with no apparent cell cycle dependency. Cyclin G2 shares 53% amino acid sequence identity with cyclin G1. Peak expression of cyclin G2 is seen in late S phase, as opposed to cyclin G1 expression, which is constitutive.

General readings

Horne M.C., et al. (1996) J. Biol. Chem. 271:6050-6061Bates S.A., et al. (1996) Oncogene. 13:1103-1109

3 Item(s)

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Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Cyclin G1 (full length, C-term DDK tag, transcript variant 2)

  Purified recombinant protein of Human cyclin G1 (CCNG1), transcript variant 2, full length, with C-terminal DDK tag, expressed in sf9, 20ug  
Cyclin G1 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
SF9 cells
20 µg / €399.00
  OriGene Technologies, Inc.

Cyclin G1 (1-295, His-tag)

Cyclin G1 Human Purified > 85 % by SDS - PAGE E. coli
0.25 mg / €730.00
  OriGene Technologies GmbH

Cyclin G1 (1-295, His-tag)

Cyclin G1 Human Purified > 85 % by SDS - PAGE E. coli
50 µg / €300.00
  OriGene Technologies GmbH

3 Item(s)

per page
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