Cyclin G1 antibody

Principal name

Cyclin G1 antibody

Alternative names for Cyclin G1 antibody

Cyclin-G1, Cyclin-G, CCNG1, CCNG, CYCG1

SwissProt ID

P39950 (Rat), P51945 (Mouse), P51959 (Human), Q52QT8 (Pig), Q5E9I1 (Bovin)

Gene ID

900 (CCNG1), 12450 (Ccng1), 25405

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Can (Canine), Por (Porcine)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Flow Cytometry (F)

Background of Cyclin G1 antibody

Cyclins are the regulatory subunits of Cdc2 p34 and related cyclin-dependent kinases (Cdks) which play critical roles in the control of cell cycle progression. The catalytic subunit for cyclin A and B is Cdc2 p34 kinase. The Cdc2- cyclin B complex controls the G2 to M transition whereas Cdc2-cyclin A regulates S phase progression. The G1 to S transition, however, appears to be controlled by the G1 cyclins. Cyclin D1 accumulates during G1 and associates with Cdk2, Cdk4 and Cdk5. Cyclin E and Cdk2 interact during the G1 to S transition. Cyclin G contains a typical N terminal cyclin box and a carboxy terminal domain sequence homologous to the tyrosine phosphorylation site of the epidermal growth factor receptor. Cyclin G expression is induced within 3 hours after growth stimulation and remains elevated with no apparent cell cycle dependency. Cyclin G2 shares 53% amino acid sequence identity with cyclin G1. Peak expression of cyclin G2 is seen in late S phase, as opposed to cyclin G1 expression, which is constitutive.

General readings

Horne M.C., et al. (1996) J. Biol. Chem. 271:6050-6061Bates S.A., et al. (1996) Oncogene. 13:1103-1109

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Cyclin G1 (C-term) antibody

CCNG1 Antibody (C-term) (Cat. #AP50811PU-N) western blot analysis in mouse kidney tissue lysates (35µg/lane).This demonstrates the CCNG1 antibody detected the CCNG1 protein (arrow). Rabbit Ig Purified Hu, Ms F, WB
0.4 ml / €370.00
  OriGene Technologies GmbH

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