Cyclin L1 antibody

Principal name

Cyclin L1 antibody

Alternative names for Cyclin L1 antibody

Cyclin-L1, Cyclin-L, CCNL1, BM-001

SwissProt ID

Q52KE7 (Mouse), Q5ZJP9 (Chick), Q6GN15 (Xenla), Q9R1Q2 (Rat), Q9UK58 (Human)

Gene ID

57018 (CCNL1)

Available reactivities

Hu (Human), Bov (Bovine), Ms (Mouse), Rt (Rat), Can (Canine), Chk (Chicken), Chimp (Chimpanzee), Mky (Monkey), Por (Porcine), GP (Guinea Pig), Rb (Rabbit)

Available hosts

Mouse, Rabbit

Available applications

Enzyme Immunoassay (E), Immunocytochemistry/Immunofluorescence (ICC/IF), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P), Immunoprecipitation (IP), Frozen Sections (C)

Background of Cyclin L1 antibody

Cell proliferation is controlled at specific stages of the cell cycle by distinct protein kinase complexes. These complexes consist of a catalytic subunit associating with a specific regulatory subunit to form the active kinase. The cyclins, which include cyclin A, B, C, D, E, F, G, H, I, K, L, T and their related proteins, including Dbf4, comprise the regulatory subunits of these kinase complexes. The controlled activation of the kinase complexes at various intervals of the cell cycle is regulated by the availability of the cyclins to the catalytic subunit. Unlike the catalytic subunit, which is expressed continually, the expression and stability of the regulatory subunit fluctuates depending on the stage of the cell cycle and, thereby, regulates the kinase activity. Cyclin L1 is a ubiquitously expressed nuclear protein that can be detected in higher levels in thymus. In neck and head squamous cell carcinomas, cyclin L1 can be overexpressed and is therefore often considered a proto-oncogene. It interacts with POLR2A, CDC2L and SFRS2. Cyclin L1 plays a role in the mRNA splicing process regulation.

General readings

Clark,H.F., et al., (2003) Genome Res. 13 (10), 2265-2270

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Cyclin L1 antibody

Western blot analysis of extracts from HepG2 cells, using Cyclin-L1 antibody (#TA315638).The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cyclin L1 antibody

WB Suggested Anti-CCNL1 Antibody Titration: 2.5ug/ml; ELISA Titer: 1: 62500; Positive Control: HepG2 cell lysateCCNL1 is supported by BioGPS gene expression data to be expressed in HepG2 Rabbit IgG Purified Bov, GP, Hu, Ms, Rb, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cyclin L1 antibody

Western blot analysis on HepG2 cell lysate using Cyclin L1 Antibody Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cyclin L1 antibody

Immunohistochemistry (IHC) analyzes of Cyclin-L1 antibody (Cat.-No.: AP06277PU-N) in paraffin-embedded human breast carcinoma lung carcinoma tissue. Rabbit Aff - Purified Hu, Ms, Rt P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Cyclin L1 antibody

Figure 1. Staining CCNL1 in Thymus by Immunohistochemistry using Formalin-Fixed Paraffin-Embedded (FFPE) tissue. Rabbit Purified Can, Chk, Hu, Ms, Rt E, IP, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Cyclin L1 antibody

Figure 1. Staining CCNL1 in Skeletal Muscle by Immunohistochemistry using Formalin-Fixed Paraffin-Embedded (FFPE) tissue. Rabbit Purified Hu E, IP, P, WB
50 µg / €470.00
  Acris Antibodies GmbH

Cyclin L1 antibody

Immunofluorescence of purified MaxPab antibody to CCNL1 on HeLa cell. [antibody concentration 10 ug/ml] Mouse Serum Hu E(detection), ICC/IF, WB
50 µl / €370.00
  Abnova Taiwan Corp.

Cyclin L1 antibody

Immunofluorescence of monoclonal antibody to CCNL1 on HeLa cell. [antibody concentration 10 ug/ml] Mouse IgG1 1F7-1C5 Purified Hu E, ICC/IF, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

Cyclin L1 antibody

Western blot using CCNL1 polyclonal antibody ( Cat # PAB9945 ) shows detectionof a band ~59 kDa corresponding to a CCNL1 ( arrowhead ) present in mouse brain whole cell lysate.
Approximately 35 µg of lysate was separated by 4-20% SDS-PAGE followed by transfer to nitrocellulose.
After blocking the membrane was probed with the primary antibody diluted to 1 : 3,500 for 2h at room temperature followed by washes and reaction with a 1 : 10,000 dilution of IRDyeTM800 conjugated Gt-a-RabbitIgG [H&L] MX for 45 min at room temperature.
IRDyeTM800 fluorescence image was captured using the Odyssey® Infrared Imaging System developed by LI-COR.
IRDye is a trademark of LI-COR, Inc. Chimp, Chk, Hu, Ms, Rt
0.5 mg / €560.00
  Abnova Taiwan Corp.

Cyclin L1 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Cyclin L1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €205.00
  Assay Biotech

Cyclin L1 antibody

Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using Cyclin L1 Antibody. The picture on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €310.00
  Assay Biotech

Cyclin L1 antibody

Human HepG2; WB Suggested Anti-CCNL1 Antibody Titration: 2.5ug/ml. ELISA Titer: 1:62500. Positive Control: HepG2 cell lysate. CCNL1 is supported by BioGPS gene expression data to be expressed in HepG2.; CCNL1 antibody - N-terminal region (ARP33174_T100) in Human HepG2 cells using Western Blot Rabbit Aff - Purified Bov, Hu, Ms, Rt WB
0.1 mg / €310.00
  AVIVA Systems Biology

Cyclin L1 antibody

Immunohistochemical analysis of Cyclin L1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rt P, WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

Cyclin L1 antibody

Immunohistochemical analysis of Cyclin L1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rt P, WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

Cyclin L1 antibody

Immunohistochemical analysis of Cyclin L1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Rabbit Aff - Purified Bov, Can, Hu, Ms, Por, Rt P, WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

Cyclin L1 antibody

Cyclin L1 Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
0.1 mg / €360.00
  Novus Biologicals Inc.

Cyclin L1 antibody

Cyclin L1 Rabbit IgG Aff - Purified Hu, Ms, Rt E, P, WB
50 µg / €290.00
  Novus Biologicals Inc.

Cyclin L1 antibody

Immunohistochemistry-Paraffin: CCNL1 Antibody [NBP1-77747] - Cyclin L1/L2 (isoform 2) antibody was used at a 10 ug/ml to detect cyclin L in a variety of tissues including breast, kidney, liver, lung, skeletal muscle, pancreas, prostate and spleen. In some tissues elevated background staining was noted. In these instances further optimization of dilution is suggested. This image shows Cyclin L staining of human skeletal muscle. Rabbit Purified Hu, Ms, Rt E, IP, P, WB
0.5 mg / €480.00
  Novus Biologicals Inc.

Cyclin L1 antibody

Immunohistochemistry-Paraffin: FBXO31 Antibody [NBP1-77748] anti-Fbp5a antibody shows strong cytoplasmic and membranous staining of bile duct cells in human liver tissue. Tissue was formalin-fixed and paraffin embedded. Brown color indicates presence of protein, blue color shows cell nuclei. Rabbit Aff - Purified Hu, Mky E, P, WB
0.1 mg / €510.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

Cyclin L1

Cyclin L1 Human 12.5% SDS-PAGE Stained with Coomassie Blue. in vitro transl.
10 µg / €380.00
  Abnova Taiwan Corp.

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