Cyclooxygenase 1 antibody

Principal name

Cyclooxygenase 1 antibody

Alternative names for Cyclooxygenase 1 antibody

PGH synthase 1, PGHS-1, COX-1, COX1, PTGS1, Cyclooxygenase-1, Prostaglandin G/H synthase 1, Prostaglandin-endoperoxide synthase 1, Prostaglandin H2 synthase 1

SwissProt ID

O62664 (Bovin), O97554 (Rabit), P05979 (Sheep), P22437 (Mouse), P23219 (Human), Q63921 (Rat)

Gene ID

5742 (PTGS1), 19224 (Ptgs1), 443551

Available reactivities

Hu (Human), Ms (Mouse), Rt (Rat), Bov (Bovine), Sh (Sheep), Chk (Chicken), Mam (Mammalia), Can (Canine), Por (Porcine), Rb (Rabbit), Ze (Zebrafish), African clawed frog, GP (Guinea Pig)

Available hosts

Rabbit, Mouse, Goat

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Paraffin Sections (P), Frozen Sections (C), Flow Cytometry (F), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Cyclooxygenase 1 antibody

Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis.Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis. Alternative splicing of this gene generates two transcript variants. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors.Prostaglandin-endoperoxide synthase (PTGS), also known as cyclooxygenase, is the key enzyme in prostaglandin biosynthesis, and acts both as a dioxygenase and as a peroxidase. There are two isozymes of PTGS: a constitutive PTGS1 and an inducible PTGS2, which differ in their regulation of expression and tissue distribution. This gene encodes PTGS1, which regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. PTGS1 is thought to be involved in cell-cell signaling and maintaining tissue homeostasis. Alternative splicing of this gene generates two transcript variants. The expression of these two transcripts is differentially regulated by relevant cytokines and growth factors. Polyclonal antibody produced in rabbits immunized with a synthetic peptide corresponding to a region of Human PTGS1 with an internal ID of P10884

General readings

General / background references:DeWitt DL et al. Concentrations of prostaglandin endoperoxide synthase and prostaglandin I2 synthase in the endothelium and smooth muscle of bovine aorta. J Clin Invest 72:1882-8 (1983). PubMed PMID: 6417165
Pagels WR et al. Immunochemical evidence for the involvement of prostaglandin H synthase in hydroperoxide-dependent oxidations by ram seminal vesicle microsomes. J Biol Chem 258:6517-23 (1983). PubMed PMID: 6406484
Smith WL & Rollins TE Characteristics of rabbit anti-PGH synthase antibodies and use in immunocytochemistry. Methods Enzymol 86:213-22 (1982). PubMed PMID: 6813638
Baroffio R & Ricci A [Acute articular rheumatism: a new apex-cardiographic index for evaluation of cardiac involvement?] Reumatismo 29:93-5 (1977). PubMed PMID: 616971

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Cyclooxygenase 1 antibody

AP15502PU COX1 antibody staining of Human Esophagus Carcinoma. Rabbit Purified Hu P
0.5 ml / €360.00
  Acris Antibodies GmbH

Cyclooxygenase 1 antibody

AP15502PU COX1 antibody staining of Human Esophagus Carcinoma. Rabbit Purified Hu P
1 ml / €520.00
  Acris Antibodies GmbH

Cyclooxygenase 1 antibody

AP15502PU COX1 antibody staining of Human Esophagus Carcinoma. Rabbit Purified Hu P
0.1 ml / €190.00
  Acris Antibodies GmbH

Cyclooxygenase 1 (C-term) antibody

TA302656 staining (1µg/ml) of HeLa lysate (RIPA buffer, 30µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Purified Hu E, P, WB
20 µg / €200.00
  Acris Antibodies GmbH

Cyclooxygenase 1 (C-term) antibody

TA302656 staining (1µg/ml) of HeLa lysate (RIPA buffer, 30µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Purified Hu E, P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cyclooxygenase 1 antibody

Western blot analysis of Jurkat cells (Lanes 1 and 2: 62ug cell lysate) with anti-COX1 antibody. (Predicted band size: 70kDa; observed band size: 50kDa) Rabbit IgG Purified Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cyclooxygenase 1 antibody

Western blot analysis of Cox-3 with mouse small intestine tissue lysate. Rabbit Purified Ms WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cyclooxygenase 1 antibody

Predicted band size: 69 kDa . Positive control: NIH/3T3 and 293T cell lysate. Recommended dilution: 1/ 100-500. (Gel: 8%SDS-PAGE Lane1: NIH/3T3 cell lysate Lane2: 293T cell lysate Lysates: 30 ug per lane Primary antibody: 1/200 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 1 minute) Rabbit IgG Purified Hu, Ms E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cyclooxygenase 1 antibody

Predicted cell location: Cytoplasm . Positive control: Human stomach cancer tissue. Recommended dilution: 1/20-100  The image on the left is immunohistochemistry of paraffin-embedded Human stomach cancer tissue using PTGS1 antibody at dilution 1/20, on the right is treated with the synthetic peptide. (Original magnification:x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cyclooxygenase 1 antibody

Predicted cell location: Cytoplasm . Positive control: Human testis tissue. Recommended dilution: 1/25-100  The image on the left is immunohistochemistry of paraffin-embedded Human testis tissue using PTGS1 antibody at dilution 1/30, on the right is treated with the synthetic peptide. (Original magnification: x200) Rabbit IgG Purified Hu, Ms, Rt E, P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cyclooxygenase 1 antibody

PTGS1 Antibody (C-term) (Cat. #TA324737) western blot analysis in A431,K562 cell line lysates (35ug/lane).This demonstrates the PTGS1 antibody detected the PTGS1 protein (arrow). Rabbit IgG Purified Hu ICC/IF, P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

Cyclooxygenase 1 antibody

Western blot analysis of Cox1 expression in HuvEc whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cyclooxygenase 1 antibody

Western blot analysis on HuvEc cell lysate using Cox1 Antibody Rabbit IgG Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cyclooxygenase 1 antibody

Western Blot: COX1 Antibody - Western Blot was performed using affinity purified SEQer PTGS1 antibody. The lanes contain 5-30ug of a whole cell extract.  Final concentration of antibodies = 0.1ug/ml (1:10,000 dilution). Rabbit IgG Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cyclooxygenase 1 antibody

Cyclooxygenase 1 Mouse IgG1 AS70 Purified Hu WB
0.1 mg / €370.00
  Acris Antibodies GmbH

Cyclooxygenase 1 Control Peptide

Cyclooxygenase 1 Purified
50 µg / €190.00
  Acris Antibodies GmbH

Cyclooxygenase 1 antibody

Cyclooxygenase 1 Rabbit Aff - Purified Hu, Ms, Rt IP, WB
0.1 mg / €370.00
  Acris Antibodies GmbH

Cyclooxygenase 1 antibody

Cyclooxygenase 1 Goat IgG Serum Chk, Mam, Ms, Rt, Sh E, WB
0.1 ml / €330.00
  Acris Antibodies GmbH

Cyclooxygenase 1 antibody

Immunohistochemical analysis using Cyclooxygenase 1 antibody (Cat.-No. AP06072PU-N) in paraffin-embedded human brain tissue. Rabbit Aff - Purified Hu P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

Cyclooxygenase 1 (C-term) antibody

Human Skin (formalin-fixed, paraffin-embedded) stained with PTGS1 antibody AP22736PU-N at 15 µg/ml followed by biotinylated goat anti-rabbit IgG secondary antibody, alkaline phosphatase-streptavidin and chromogen. Rabbit Aff - Purified Hu P
0.5 ml / €470.00
  Acris Antibodies GmbH

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