Cyclooxygenase 2 antibody

Principal name

Cyclooxygenase 2 antibody

Alternative names for Cyclooxygenase 2 antibody

Cyclooxygenase-2, PTGS2, COX2, PHS II, PGH synthase 2, PGHS-2, PGHS2, Prostaglandin G/H synthase 2, Prostaglandin-endoperoxide synthase 2, Prostaglandin H2 synthase 2

SwissProt ID

O02768 (Rabit), O19183 (Horse), O62698 (Bovin), P27607 (Chick), P35354 (Human), P35355 (Rat), P70682 (Cavpo), P79208 (Sheep), Q05769 (Mouse)

Gene ID

5743 (PTGS2), 19225 (Ptgs2), 29527, 443460

Available reactivities

Bov (Bovine), Eq (Equine), Hu (Human), Sh (Sheep), Ms (Mouse), Rt (Rat), Por (Porcine), Can (Canine)

Available hosts

Rabbit, Mouse, Goat

Available applications

Western blot / Immunoblot (WB), Paraffin Sections (P), Frozen Sections (C), Flow Cytometry (F), Enzyme Immunoassay (E), Immunoprecipitation (IP), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF)

Background of Cyclooxygenase 2 antibody

Cyclooxygenase (COX), also known as Prostaglandin H2 synthase and Prostaglandin endoperoxide synthase, is a key enzyme in the of conversion arachidonic acid to Prostaglandin H2. Prostaglandin H2 is converted by other enzymes into inflammatory mediators prostaglandin (PG) D2, PGE2, PGF2a, PGI2 and Thromboxane A2. Thus, COX is a key enzyme in the production of inflammatory agents and is the target of intense research and drug discovery activities. There are two enzymes of COX, COX-1 and COX-2. COX-1 is constitutively produced in many (most) cell types. It is important in the gut for the production of prostaglandins, which inhibit gastric secretion. It can be induced in monocytes, macrophages and other cells. It is induced as part of the inflammatory response by IL-1beta and other cytokines. It is induced by growth factors such as EGF and PDGF. Expression is inhibited by glucocorticosteroids such as cortisol and dexamethasone. Lipopolysaccharide in bacterial infections induces COX-2. COX-2 is also found in elevated levels in synoviocytes from rheumatoid arthritis patients. The discomforts of inflammation such as pain and swelling are largely due to the action of prostaglandins produced by COX-2.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

Cyclooxygenase 2 antibody

AM05211PU-N COXII antibody staining of Human bladder tumor section. Mouse IgG1 AS66 Purified Hu C, WB
0.1 mg / €380.00
  Acris Antibodies GmbH

Cyclooxygenase 2 antibody

  Rabbit polyclonal anti-Cox2 (PTGS2) antibody  
Western blot analysis of extracts from A549 cells, using Cox2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt ICC/IF, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cyclooxygenase 2 antibody

  Rabbit Monoclonal anti-COX-2 Antibody  
Human colon adenocarcinoma stained with anti-COX-2 antibody. Rabbit IgG SP21 Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cyclooxygenase 2 (C-term) antibody

  Goat Polyclonal Antibody against PTGS2  
TA302755 staining (0.5µg/ml) of H460 lysate (RIPA buffer, 35µg total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. Goat Aff - Purified Bov, Can, Hu, Por E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cyclooxygenase 2 antibody

  Rabbit polyclonal anti-Cox-2 antibody  
anti-Cox2 is shown to detect Cox-2 present in Cox-2 transfected Sf9 cell extract (lane 1) and IL-1ß induced WISH cell extract (lane 2). Detection occurs using a 1:10,000 dilution of antibody followed by 1:10,000 dilution of HRP Goat-a-Rabbit with visualization via ECL. Film exposure approximately 1’. Other detection systems will yield similar results. Rabbit Serum Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cyclooxygenase 2 antibody

  Rabbit Polyclonal Cox2 (PTGS2) Antibody  
Western blot analysis of Cox2 expression in A549 whole cell lysates,The lane on the left is treated with the antigen-specific peptide. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cyclooxygenase 2 antibody

  Rabbit Polyclonal anti-COX-2 Antibody  
Human Breast Carcinoma stained with anti-COX-2 antibody. Rabbit IgG Purified Hu P
0.1 ml / €325.00
  OriGene Technologies, Inc.

Cyclooxygenase 2 antibody

  Rabbit Polyclonal COX2 Antibody  
ELISA: COX2 Antibody Rabbit IgG Purified Hu, Ms E
0.1 mg / €325.00
  OriGene Technologies, Inc.

Cyclooxygenase 2 antibody

  PTGS2 mouse monoclonal antibody, clone OTI4C4 (formerly 4C4)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PTGS2 (RC202245, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PTGS2. Mouse IgG2a OTI4C4 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Cyclooxygenase 2 antibody

  PTGS2 mouse monoclonal antibody, clone OTI5F12 (formerly 5F12)  
Immunohistochemical staining of paraffin-embedded Carcinoma of Human pancreas tissue using anti-PTGS2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA805286) Mouse IgG2b OTI5F12 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Cyclooxygenase 2 antibody

  PTGS2 mouse monoclonal antibody, clone OTI1B4 (formerly 1B4)  
Immunohistochemical staining of paraffin-embedded Human Kidney tissue within the normal limits using anti-PTGS2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA805287) Mouse IgG1 OTI1B4 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Cyclooxygenase 2 antibody

  PTGS2 mouse monoclonal antibody, clone OTI10H5 (formerly 10H5)  
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-PTGS2 mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min, TA805307) Mouse IgG2a OTI10H5 Purified Hu P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Cyclooxygenase 2 antibody

  PTGS2 mouse monoclonal antibody, clone OTI6D10 (formerly 6D10)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PTGS2 (RC202245, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PTGS2. Mouse IgG1 OTI6D10 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Cyclooxygenase 2 antibody

  PTGS2 mouse monoclonal antibody, clone OTI2F10 (formerly 2F10)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PTGS2 (RC202245, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PTGS2. Mouse IgG1 OTI2F10 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Cyclooxygenase 2 antibody

  PTGS2 mouse monoclonal antibody, clone OTI9H10 (formerly 9H10)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PTGS2 (RC202245, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PTGS2. Mouse IgG1 OTI9H10 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Cyclooxygenase 2 antibody

  PTGS2 mouse monoclonal antibody, clone OTI2E1 (formerly 2E1)  
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PTGS2 (RC202245, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-PTGS2. Mouse IgG1 OTI2E1 Purified Hu WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

TrueMAB

Cyclooxygenase 2 antibody

Cyclooxygenase 2 Mouse IgG1 AS66 FITC Hu F
100 Tests / €380.00
  Acris Antibodies GmbH

Cyclooxygenase 2 antibody

Cyclooxygenase 2 Mouse IgG1 AS73 Purified Hu, Rt WB
0.1 mg / €380.00
  Acris Antibodies GmbH

Cyclooxygenase 2 Control Peptide

Cyclooxygenase 2 Purified
50 µg / €190.00
  Acris Antibodies GmbH

Cyclooxygenase 2 antibody

Western blot analysis of Cox-2 expression in Jurkat cell lysates. Rabbit Aff - Purified Bov, Eq, Hu, Sh WB
0.1 mg / €370.00
  Acris Antibodies GmbH

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