CYFIP1 antibody

Principal name

CYFIP1 antibody

Alternative names for CYFIP1 antibody

p140sra-1, KIAA0068, Cytoplasmic FMR1-interacting protein 1, Specifically Rac1-associated protein 1

SwissProt ID

P85091 (Bovin), Q7L576 (Human), Q7TMB8 (Mouse)

Gene ID

23191 (CYFIP1)

Available reactivities

Hu (Human), Ms (Mouse), Bov (Bovine), Can (Canine), Rt (Rat), Macaque, Prim (Primate), Eq (Equine), GP (Guinea Pig), Gt (Goat), Rb (Rabbit), Ze (Zebrafish)

Available hosts

Rabbit, Goat

Available applications

Immunoprecipitation (IP), Western blot / Immunoblot (WB), Immunocytochemistry/Immunofluorescence (ICC/IF), Paraffin Sections (P), Enzyme Immunoassay (E)

Background of CYFIP1 antibody

CYFIP1 is a component of the CYFIP1-EIF4E-FMR1 complex which binds to the mR cap and mediates translatiol repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. CYFIP1 promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mR By similarity. CYFIP1 regulates formation of membrane ruffles and lamellipodia. CYFIP1 plays a role in axon outgrowth. CYFIP1 binds to F-actin but not to R. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Regulator of epithelial morphogenesis. CYFIP1 may act as an invasion suppressor in cancers.

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CYFIP1 antibody

WB Suggested Anti-CYFIP1 Antibody; Titration: 1.0 ug/ml; Positive Control: COLO205 Whole Cell Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Rb, Rt, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

CYFIP1 antibody

Western Blot: CYFIP1 Antibody [NBP1-50028] - Western Blot: CYFIP1 Antibody [NBP1-50028] - Detection of Human CYFIP1 by Western Blot and Immunoprecipitation. Samples:  Whole cell lysate from HeLa (5, 15 and 50 mcg for WB; 1 mg for IP, 20% of IP loaded) and 293T (T; 50 mcg) cells.  Antibodies: Affinity purified rabbit anti-CYFIP1 antibody used for WB at 0.4 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 6 mcg/mg lysate.  CYFIP1 was also immunoprecipitated by rabbit anti-CYFIP1 antibody BL10812, which recognizes an upstream epitope.  For blotting immunoprecipitated CYFIP1, the ReliaBLOT®  Reagents and Procedures were used.  Detection: Chemiluminescence with exposure times of 3 minutes (A) and 30 seconds (B). Rabbit Aff - Purified Hu IP, WB
0.1 mg / €440.00
  Novus Biologicals Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CYFIP1

CYFIP1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
10 µg / €380.00
  Abnova Taiwan Corp.

CYFIP1

CYFIP1 Human Purified 12.5% SDS-PAGE Stained with Coomassie Blue.
25 µg / €510.00
  Abnova Taiwan Corp.

Lysates

Catalog No.    

CYFIP1 overexpression lysate

CYFIP1 overexpression lysate  
0.1 mg / €280.00
  OriGene Technologies, Inc.

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