CYP1A1 antibody

Principal name

CYP1A1 antibody

Alternative names for CYP1A1 antibody

Cytochrome P450 1A1, Cytochrome P450-P1, Cytochrome P450 form 6, Cytochrome P450-C

SwissProt ID

P00184 (Mouse), P00185 (Rat), P04798 (Human), P05176 (Rabit), P56590 (Canfa), P56591 (Sheep), Q06367 (Cavpo), Q5KQT7 (Felca)

Gene ID

1543 (CYP1A1), 24296 (Cyp1a1), 13076

Available reactivities

Hu (Human), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), Eq (Equine), Can (Canine), Mky (Monkey), Sh (Sheep), Ze (Zebrafish), Bov (Bovine), GP (Guinea Pig), Gt (Goat)

Available hosts

Rabbit, Mouse, Goat

Available applications

Western blot / Immunoblot (WB), Functional assay (FN), Paraffin Sections (P), ELISA (detection) (E(detection)), Immunocytochemistry/Immunofluorescence (ICC/IF), Immunoprecipitation (IP), Enzyme Immunoassay (E), Frozen Sections (C)

Background of CYP1A1 antibody

CYP1A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme\'s endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. CYP1A1 has been associated with lung cancer risk. This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme\'s endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

General readings

General / background references:Gonzalez FJ The study of xenobiotic-metabolizing enzymes and their role in toxicity in vivo using targeted gene disruption. Toxicol Lett 102-103:161-6 (1998). PubMed PMID: 10022249
Brosen K Drug interactions and the cytochrome P450 system. The role of cytochrome P450 1A2. Clin Pharmacokinet 29 Suppl 1:20-5 (1995). PubMed PMID: 8846619

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CYP1A1 antibody

Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using CYP1A1 mouse mAb with DAB staining. Mouse IgG1 6G5 Purified Hu E, P, WB
0.1 mg / €430.00
  Acris Antibodies GmbH

CYP1A1 antibody

TA309533 (0.1µg/ml) staining of Rat Lung lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Ms, Rt E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CYP1A1 antibody

Western blot analysis of extracts from COS-7 cells, RAW264.7 cells and HT-29 cells, using Cytochrome P450 1A1/2 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CYP1A1 antibody

Predicted band size: 58 kDa . Positive control: Mouse liver tissue lysate. Recommended dilution: 1/500-2000. (Gel: 10%SDS-PAGE Lysate: 30 ug Primary antibody: 1/500 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 5 seconds) Rabbit IgG Purified Hu, Ms, Rt E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CYP1A1 antibody

Gel: 10%SDS-PAGE, Lysate: 30 µg, Lane: Mouse liver tissue, Primary antibody:CYP1A1 Antibody at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds Rabbit IgG Purified Hu, Ms, Rt E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CYP1A1 antibody

Western blot analysis of extracts of various cell lines, using CYP1A1 antibody. Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CYP1A1 antibody

TA329676 (0.3ug/ml) staining of A549 (A) and MCF7 (B) lysates (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Goat Aff - Purified Hu E, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CYP1A1 antibody

WB Suggested Anti-CYP1A1 Antibody Titration: 0.2-1 ug/ml; Positive Control: Hela cell lysate Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Rb, Rt, Sh, Ze P, WB
50 µg / €325.00
  OriGene Technologies, Inc.

CYP1A1 antibody

WB Suggested Anti-CYP1A1 Antibody Titration: 0.2-1 ug/ml; Positive Control: Human heart Rabbit IgG Purified Bov, Can, Eq, GP, Gt, Hu, Ms, Por, Rb, Rt, Sh, Ze WB
50 µg / €325.00
  OriGene Technologies, Inc.

CYP1A1 antibody

Western blot analysis of Cytochrome P450 1A1/2 expression in RAW264.7 cells Rabbit IgG Purified Hu, Ms, Rt WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CYP1A1 (C-term) antibody

Figure 2. Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with CYP1A1 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Rabbit Ig Purified Hu, Ms P, WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CYP1A1 (C-term) antibody

Western blot analysis of anti-CYP1A1 Antibody (Center) in mouse lung tissue lysates (35ug/lane). CYP1A1 (arrow) was detected using the purified Pab. Rabbit Ig Purified Hu WB
0.4 ml / €370.00
  Acris Antibodies GmbH

CYP1A1 (+CYP1A2) antibody

Western blot (WB) analysis of CYP1A1/2 Antibody Cat.-No AP20396PU-N in extracts from RAW264.7 cells. Rabbit Aff - Purified Hu, Ms, Rt ICC/IF, P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CYP1A1 antibody

CYP1A1 Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

CYP1A1 antibody

CYP1A1 Rabbit Serum Hu E(detection), IP, WB
0.1 ml / €380.00
  Abnova Taiwan Corp.

CYP1A1 antibody

Western Blot analysis of CYP1A1 expression in transfected 293T cell line (H00001543-T02) by CYP1A1 MaxPab polyclonal antibody.

Lane 1: CYP1A1 transfected lysate(58.20 KDa).
Lane 2: Non-transfected lysate. Rabbit Purified Hu E(detection), WB
0.1 mg / €380.00
  Abnova Taiwan Corp.

CYP1A1 antibody

CYP1A1 Mouse IgG Rt WB
50 µg / €390.00
  Abnova Taiwan Corp.

CYP1A1 (+CYP1A2) antibody

CYP1A1 Goat IgG Rb, Rt IP, WB
1 ml / €390.00
  Abnova Taiwan Corp.

CYP1A1 antibody

Western blot analysis of extracts from COS7/RAW264.7/HT-29 cells, using Cytochrome P450 1A1/2 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
50 µg / €205.00
  Assay Biotech

CYP1A1 antibody

Western blot analysis of extracts from COS7/RAW264.7/HT-29 cells, using Cytochrome P450 1A1/2 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu, Ms, Rt E, WB
0.1 mg / €310.00
  Assay Biotech

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