CYP2D6 antibody

Principal name

CYP2D6 antibody

Alternative names for CYP2D6 antibody

CYP2DL1, Cytochrome P450 2D6, CYPIID6, Cytochrome P450-DB1, Debrisoquine 4-hydroxylase

SwissProt ID

P10635 (Human)

Gene ID

1565 (CYP2D6)

Available reactivities

Hu (Human), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), Ze (Zebrafish), Mky (Monkey), Bov (Bovine), Can (Canine), Eq (Equine), GP (Guinea Pig), Sh (Sheep)

Available hosts

Mouse, Rabbit, Sheep

Available applications

Enzyme Immunoassay (E), Western blot / Immunoblot (WB), ELISA (detection) (E(detection)), Paraffin Sections (P), Immunoprecipitation (IP)

Background of CYP2D6 antibody

CYP2D6 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20% of commonly prescribed drugs. Its substrates include debrisoquine, an adrenergic-blocking drug; sparteine and propafenone, both anti-arrythmic drugs; and amitryptiline, an anti-depressant.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20% of commonly prescribed drugs. Its substrates include debrisoquine, an adrenergic-blocking drug; sparteine and propafenone, both anti-arrythmic drugs; and amitryptiline, an anti-depressant. The gene is highly polymorphic in the population; certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme\'s substrates. The gene is located near two cytochrome P450 pseudogenes on chromosome 22q13.1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

General readings

Rowland,P., (2006) J. Biol. Chem. 281 (11), 7614-7622

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CYP2D6 antibody

  Rabbit polyclonal Cytochrome P450 2D6 antibody  
Western blot analysis of extracts from HT-29 cells, using Cytochrome P450 2D6 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CYP2D6 antibody

  Rabbit polyclonal Cytochrome P450 2D6 antibody  
Western blot analysis of extracts from 293 cells, using Cytochrome P450 2D6 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CYP2D6 antibody

  Rabbit polyclonal anti-CYP2D6 antibody  
Western blot analysis of extracts from K562 cells, using CYP2D6 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CYP2D6 antibody

  Rabbit polyclonal anti-CYP2D6 antibody  
Western blot analysis of extracts from 293/Jurkat/K562 cells, using CYP2D6 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CYP2D6 antibody

  Rabbit polyclonal anti-CYP2D6 antibody  
Western blot analysis of extracts from HeLa cells, using CYP2D6 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CYP2D6 antibody

  Rabbit polyclonal CYP2D6 Antibody (N-term)  
CYP2D6 Antibody (N-term) (Cat. #TA324552) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the CYP2D6 antibody detected the CYP2D6 protein (arrow). Rabbit IgG Purified Hu, Rt P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

CYP2D6 antibody

  Rabbit Polyclonal Anti-CYP2D6 Antibody  
WB Suggested Anti-CYP2D6 Antibody Titration: 2.5 ug/ml; Positive Control: Human Liver Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Sh, Ze P, WB
0.1 mg / €325.00
  OriGene Technologies, Inc.

CYP2D6 antibody

  Rabbit Polyclonal Anti-CYP2D6 Antibody  
WB Suggested Anti-CYP2D6 Antibody Titration: 0.2-1 ug/ml; ELISA Titer: 1: 1562500; Positive Control: OVCAR-3 cell lysateCYP2D6 is strongly supported by BioGPS gene expression data to be expressed in Human OVCAR3 cells Rabbit IgG Purified Bov, Can, Eq, GP, Hu, Ms, Por, Rb, Rt, Sh WB
50 µg / €325.00
  OriGene Technologies, Inc.

CYP2D6 antibody

  Rabbit Polyclonal Anti-CYP2D6 Antibody  
Gel: 8%SDS-PAGE, Lysate: 40 ug, Lane: K562 cells, Primary antibody: (CYP2D6 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 minutes Rabbit IgG Purified Hu E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CYP2D6 antibody

  Sheep polyclonal anti-Cytochrome P450 2D6 antibody  
CYP2D6 Sheep IgG Purified Hu WB
100 µl / €325.00
  OriGene Technologies, Inc.

CYP2D6 antibody

Western blot (WB) analysis of CYP2D6 antibody (Cat.-No.: AP01245PU-N) in extracts from HT-29 cells. Rabbit Aff - Purified Hu P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CYP2D6 antibody

Western blot analysis of extracts from HT-29 cells, using Cytochrome P450 2D6 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €230.00
  Assay Biotech

CYP2D6 antibody

Western blot analysis of extracts from HT-29 cells, using Cytochrome P450 2D6 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €330.00
  Assay Biotech

CRISPR

Catalog No. Species Donor Vector  

CYP2D6 - human gene knockout kit via CRISPR

CYP2D6 - human gene knockout kit via CRISPR Human GFP-Puro
1 kit / €1,200.00
  OriGene Technologies, Inc.

CYP2D6 - human gene knockout kit via CRISPR

CYP2D6 - human gene knockout kit via CRISPR Human mBFP-Neo
1 kit / €1,290.00
  OriGene Technologies, Inc.

CYP2D6 - human gene knockout kit via CRISPR

CYP2D6 - human gene knockout kit via CRISPR Human Luciferase-Puro
1 kit / €1,290.00
  OriGene Technologies, Inc.

CYP2D6 - human gene knockout kit via CRISPR

CYP2D6 - human gene knockout kit via CRISPR Human RFP-BSD
1 kit / €1,290.00
  OriGene Technologies, Inc.

Proteins & Growth Factors

Catalog No. Species Pres. Purity Source  

CYP2D6 (transcript variant 2)

  Recombinant protein of human cytochrome P450, family 2, subfamily D, polypeptide 6 (CYP2D6), transcript variant 2  
CYP2D6 Human > 80 %
Preparation: Recombint protein was captured through anti-DDK affinity column followed by conventiol chromatography steps.
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells

Regular Price: 20 µg / €680.00

Special Price: 20 µg / €398.00

  OriGene Technologies, Inc.

CYP2D6 (C-term DDK tag, transcript variant 1)

  Recombinant protein of human cytochrome P450, family 2, subfamily D, polypeptide 6 (CYP2D6), transcript variant 1, with C-terminal DDK tag, expressed in human cells  
CYP2D6 Human > 80 %
Preparation: .
Purity Detail: > 80% as determined by SDS-PAGE and Coomassie blue staining.
HEK293 cells
20 µg / €680.00
  OriGene Technologies, Inc.

Human Lenti ORF Particles

Catalog No.    

Lenti ORF particles, CYP2D6 (mGFP-tagged) - Human cytochrome P450, family 2, subfamily D, polypeptide 6 (CYP2D6), transcript variant 1, 200 uL, >10^7 TU/mL

Lenti ORF particles, CYP2D6 (mGFP-tagged) - Human cytochrome P450, family 2, subfamily D, polypeptide 6 (CYP2D6), transcript variant 1, 200 uL, >10^7 TU/mL  
200 µl / €1,050.00
  OriGene Technologies, Inc.

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