CYP2D6 antibody

Principal name

CYP2D6 antibody

Alternative names for CYP2D6 antibody

CYP2DL1, Cytochrome P450 2D6, CYPIID6, Cytochrome P450-DB1, Debrisoquine 4-hydroxylase

SwissProt ID

P10635 (Human)

Gene ID

1565

Available reactivities

Hu (Human), Ms (Mouse), Por (Porcine), Rb (Rabbit), Rt (Rat), Ze (Zebrafish), Mky (Monkey)

Available hosts

Rabbit, Mouse

Available applications

Functional assay (FN), Western blot / Immunoblot (WB), Enzyme Immunoassay (E), ELISA (detection) (E(detection)), Paraffin Sections (P), Immunoprecipitation (IP)

Background of CYP2D6 antibody

CYP2D6 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20% of commonly prescribed drugs. Its substrates include debrisoquine, an adrenergic-blocking drug; sparteine and propafenone, both anti-arrythmic drugs; and amitryptiline, an anti-depressant.This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20% of commonly prescribed drugs. Its substrates include debrisoquine, an adrenergic-blocking drug; sparteine and propafenone, both anti-arrythmic drugs; and amitryptiline, an anti-depressant. The gene is highly polymorphic in the population; certain alleles result in the poor metabolizer phenotype, characterized by a decreased ability to metabolize the enzyme\'s substrates. The gene is located near two cytochrome P450 pseudogenes on chromosome 22q13.1. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

General readings

Rowland,P., (2006) J. Biol. Chem. 281 (11), 7614-7622

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Primary Antibodies

Catalog No. Host Iso. Clone Pres. React. Applications  

CYP2D6 antibody

Western blot analysis of extracts from HT-29 cells, using Cytochrome P450 2D6 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CYP2D6 antibody

Western blot analysis of extracts from 293 cells, using Cytochrome P450 2D6 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, P, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CYP2D6 antibody

Western blot analysis of extracts from K562 cells, using CYP2D6 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CYP2D6 antibody

Western blot analysis of extracts from 293/Jurkat/K562 cells, using CYP2D6 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CYP2D6 antibody

Western blot analysis of extracts from HeLa cells, using CYP2D6 antibody.The lane on the right is treated with the synthesized peptide. Rabbit IgG Purified Hu E, WB
0.1 ml / €325.00
  OriGene Technologies, Inc.

CYP2D6 antibody

CYP2D6 Antibody (N-term) (Cat. #TA324552) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the CYP2D6 antibody detected the CYP2D6 protein (arrow). Rabbit IgG Purified Hu, Rt P, WB
0.4 ml / €325.00
  OriGene Technologies, Inc.

CYP2D6 antibody

Western blot (WB) analysis of CYP2D6 antibody (Cat.-No.: AP01245PU-N) in extracts from HT-29 cells. Rabbit Aff - Purified Hu P, WB
0.1 mg / €350.00
  Acris Antibodies GmbH

CYP2D6 antibody

CYP2D6 MaxPab polyclonal antibody. Western Blot analysis of CYP2D6 expression in human liver. Mouse Purified Hu E(detection), WB
50 µg / €370.00
  Abnova Taiwan Corp.

CYP2D6 antibody

CYP2D6 monoclonal antibody (M07), clone 2C5. Western Blot analysis of CYP2D6 expression in K-562 ( Cat # L009V1 ). Mouse IgG2a 2C5 Purified Hu E, WB
0.1 mg / €370.00
  Abnova Taiwan Corp.

CYP2D6 antibody

Western blot analysis of extracts from HT-29 cells, using Cytochrome P450 2D6 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
50 µg / €205.00
  Assay Biotech

CYP2D6 antibody

Western blot analysis of extracts from HT-29 cells, using Cytochrome P450 2D6 Antibody. The lane on the right is treated with the synthesized peptide. Rabbit Aff - Purified Hu E, WB
0.1 mg / €310.00
  Assay Biotech

CYP2D6 antibody

Human Kidney; Rabbit Anti-CYP2D6 Antibody. Catalog Number: ARP41675. Paraffin Embedded Tissue: Human Kidney. Cellular Data: Epithelial cells of renal tubule. Antibody Concentration: 4.0-8.0 ug/ml. Magnification: 400X; CYP2D6 antibody - N-terminal region (ARP41675_T100) in Human Kidney cells using Immunohistochemistry Rabbit Aff - Purified Hu, Ms, Por, Rb, Rt, Ze P, WB
0.1 mg / €310.00
  AVIVA Systems Biology

CYP2D6 antibody

Human OVCAR3; WB Suggested Anti-CYP2D6 Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: OVCAR-3 cell lysate. CYP2D6 is strongly supported by BioGPS gene expression data to be expressed in Human OVCAR3 cells.; CYP2D6 antibody - middle region (ARP41676_P050) in Human OVCAR3 cells using Western Blot Rabbit Aff - Purified Hu, Rt WB
50 µg / €350.00
  AVIVA Systems Biology

CYP2D6 antibody

CYP2D6 Rabbit IgG Aff - Purified Ms, Rt P, WB
0.1 mg / €290.00
  Boster Immunoleader

CYP2D6 antibody

Western blot analysis of Cytochrome P450 2D6 expression in MCF7 (A); NIH3T3 (B); H9C2 (C) whole cell lysates. Rabbit Aff - Purified Hu, Mky, Ms, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

CYP2D6 antibody

Western blot analysis of Cytochrome P450 2D6 expression in MCF7 (A); NIH3T3 (B); H9C2 (C) whole cell lysates. Rabbit Aff - Purified Hu, Mky, Ms, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

CYP2D6 antibody

Western blot analysis of Cytochrome P450 2D6 expression in MCF7 (A); NIH3T3 (B); H9C2 (C) whole cell lysates. Rabbit Aff - Purified Hu, Mky, Ms, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

CYP2D6 antibody

Western blot analysis of Cytochrome P450 2D6 expression in MCF7 (A); NIH3T3 (B); H9C2 (C) whole cell lysates. Rabbit Aff - Purified Hu, Mky, Ms, Rt WB
30 µl / €190.00
  Cohesion Biosciences Ltd.

CYP2D6 antibody

Western blot analysis of Cytochrome P450 2D6 expression in MCF7 (A); NIH3T3 (B); H9C2 (C) whole cell lysates. Rabbit Aff - Purified Hu, Mky, Ms, Rt WB
0.1 ml / €270.00
  Cohesion Biosciences Ltd.

CYP2D6 antibody

Western blot analysis of Cytochrome P450 2D6 expression in MCF7 (A); NIH3T3 (B); H9C2 (C) whole cell lysates. Rabbit Aff - Purified Hu, Mky, Ms, Rt WB
0.2 ml / €440.00
  Cohesion Biosciences Ltd.

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